ENSMUSG00000009097


Mus musculus

Features
Gene ID: ENSMUSG00000009097
  
Biological name :Tbx1
  
Synonyms : T-box 1 / Tbx1
  
Possible biological names infered from orthology : O43435
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: A3
Gene start: 18581713
Gene end: 18586969
  
Corresponding Affymetrix probe sets: 10438347 (MoGene1.0st)   1425779_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000009241
NCBI entrez gene - 21380     See in Manteia.
MGI - MGI:98493
RefSeq - NM_011532
RefSeq - XM_017316925
RefSeq - NM_001285472
RefSeq - NM_001285476
RefSeq - XM_006521978
RefSeq - XM_006521979
RefSeq Peptide - NP_035662
RefSeq Peptide - NP_001272401
RefSeq Peptide - NP_001272405
swissprot - B9EII4
Ensembl - ENSMUSG00000009097
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tbx1ENSDARG00000031891Danio rerio
 TBX1ENSGALG00000041182Gallus gallus
 TBX1ENSG00000184058Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tbx10 / Q810F8 / T-box transcription factor TBX10 / O75333* / T-box 10*ENSMUSG0000003747746
Tbx2 / Q60707 / T-box transcription factor TBX2 / Q13207* / T-box 2*ENSMUSG0000000009332
Tbx15 / O70306 / T-box transcription factor TBX15 / Q96SF7* / T-box 15*ENSMUSG0000002786832
Tbx18 / T-box 18 / O95935*ENSMUSG0000003241932
Tbx3 / P70324 / T-box 3 / O15119*ENSMUSG0000001860431
Tbx4 / P70325 / T-box 4 / P57082*ENSMUSG0000000009430
Tbx5 / P70326 / T-box 5 / Q99593*ENSMUSG0000001826330
Tbx20 / Q9ES03 / T-box transcription factor TBX20 / Q9UMR3* / T-box 20*ENSMUSG0000003196530
Tbx22 / Q8K402 / T-box 22 / Q9Y458*ENSMUSG0000003124129
Tbx6 / P70327 / T-box transcription factor TBX6 / O95947* / T-box 6*ENSMUSG0000003069926


Protein motifs (from Interpro)
Interpro ID Name
 IPR001699  Transcription factor, T-box
 IPR008967  p53-like transcription factor, DNA-binding
 IPR018186  Transcription factor, T-box, conserved site
 IPR036960  T-box superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0048538 thymus development IEA
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IEA
 biological_processGO:0060017 parathyroid gland development IEA
 biological_processGO:0060023 soft palate development IEA
 biological_processGO:0060037 pharyngeal system development IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000018 small ears "outer ears of a smaller than normal size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Tbx1tm1Dsr/Tbx1tm1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

 MP:0000022 abnormal ear shape "malformation of the pattern of the external ear" [J:65038]
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Allelic Composition: Gsdma3Re-Den/Gsdma3Re-Den
Genetic Background: C3HeB/FeJ

 MP:0000024 lowered ear position "outer ears which are situated below the normal location " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

 MP:0000026 abnormal inner ear morphology "malformation or malfunction of any components of the labyrinth, including the semicircular canals, vestibule and cochlea" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:1776]
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Allelic Composition: Fgfr2tm1.1Dor/Fgfr2tm1.1Dor
Genetic Background: involves: 129X1/SvJ

Allelic Composition: Tbx1tm1Dsr/Tbx1tm1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1.1Dsr/Tbx1tm1.1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1Bem/Tbx1tm1Bem
Genetic Background: FVB.Cg-Tbx1tm1Bem

Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Tg(Pax2-cre)1Akg/0
Genetic Background: involves: 129/Sv * C57BL/6 * SJL

Allelic Composition: Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb,Tbx1tm6(cre)Bld/Tbx1+,Tg(Pax2-cre)1Akg/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Tbx1m1H/Tbx1m1H
Genetic Background: involves: C3H/HeH * C57BL/6J

 MP:0000029 abnormal malleus morphology "structural anomaly in the largest of the three auditory ossicles, which resembles a club or hammer " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Tbx1tm1Pa/Tbx1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * Swiss Webster

 MP:0000030 abnormal tympanic ring morphology "malformed bony ring at the ear canal to which the tympanic membrane is attached" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:23837]
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Allelic Composition: Gsdma3Re-Den/Gsdma3Re-Den
Genetic Background: C3HeB/FeJ

 MP:0000031 abnormal cochlea morphology "any anomaly, deformity, malformation, impairment or dysfunction of the cochlea" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator, J:21484]
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Allelic Composition: Gt(ROSA)26Sortm1(Tbx1/GFP)Bem/Gt(ROSA)26Sor+,Tbx1tm1Bld/Tbx1tm6(cre)Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL

 MP:0000036 absent semicircular canals "missing organ of balance; consists of three bony tubes within which the semicircular ducts are located" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:23837]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Tg(Pax2-cre)1Akg/0
Genetic Background: involves: 129/Sv * C57BL/6 * SJL

 MP:0000037 abnormal lateral semicircular canal "anomaly of the lateral long bony tube of the labyrinth that is involved in the sense of balance " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Chd7Gt(XK403)Byg/Chd7+,Tbx1tm1Bld/Tbx1+
Genetic Background: either: (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6) or (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CD-1)

Allelic Composition: Chd7Whi/Chd7+,Tbx1tm1Bld/Tbx1+
Genetic Background: B6.Cg-Chd7Whi Tbx1tm1Bld

 MP:0000039 abnormal otic capsule morphology "malformation of the cartilage or bony capsule surrounding the inner ear mechanism" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:23837]
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Allelic Composition: Tbx1tm1Pa/Tbx1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * Swiss Webster

 MP:0000040 absent middle ear ossicles "missing small bones of the tympanic cavity" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:1776]
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Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

 MP:0000049 abnormal middle ear morphology "malformation or malfunction of any components of the tympanic cavity or its ossicles" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tbx1tm1Pa/Tbx1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * Swiss Webster

Allelic Composition: Tbx1tm1Bem/Tbx1tm1Bem
Genetic Background: FVB.Cg-Tbx1tm1Bem

Allelic Composition: Tbx1tm1Bem/Tbx1+
Genetic Background: FVB.Cg-Tbx1tm1Bem

Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

 MP:0000088 short mandible "reduced length of the lower bony framework of the mouth where the inferior teeth are held" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Gsdma3Re-Den/Gsdma3Re-Den
Genetic Background: C3HeB/FeJ

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Tbx1m1Jlk/Tbx1m1Jlk
Genetic Background: 129/Sv-Tbx1m1Jlk Chrdtm1Emdr

 MP:0000111 cleft palate "congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
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Allelic Composition: Tbx1tm1Bem/Tbx1+
Genetic Background: involves: 129/Sv * C57BL/6J * SJL

Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Tbx1m1Jlk/Tbx1m1Jlk
Genetic Background: 129/Sv-Tbx1m1Jlk Chrdtm1Emdr

Allelic Composition: Tbx1m1Jlk/Tbx1m1Jlk
Genetic Background: 129/Sv-Tbx1m1Jlk

Allelic Composition: Tbx1m1Jlk/Tbx1tm1Bld
Genetic Background: involves: 129/Sv

Allelic Composition: Tbx1tm1Bld/Tbx1tm2.1Bem,Tfap2atm1(cre)Moon/Tfap2a+
Genetic Background: either: (involves: 129/Sv * C57BL/6 * SJL) or (involves: 129/Sv * C57BL/6J * CBA * SJL)

Allelic Composition: Kat6atm2.2Avo/Kat6a+,Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1m1H/Tbx1m1H
Genetic Background: involves: C3H/HeH * C57BL/6J

 MP:0000160 kyphosis "forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Tbx1tm1(Fgf8)Vite/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0000266 abnormal cardiac morphology "anomalies in the hollow, muscular organ that maintains the circulation of the blood" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Pax3tm5Buck/Pax3+
Genetic Background: involves: 129S2/SvPas

 MP:0000267 abnormal cardiac development "aberrant formation or incomplete differentiation of the heart" [MGI:cls, J:53370]
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Allelic Composition: Tfap2atm1Jae/Tfap2a+
Genetic Background: involves: 129P/Ola * 129S4/SvJae

Allelic Composition: Tbx1tm1Bld/Tbx1tm2Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0000277 abnormal heart shape "malformation of the form or the patterning of the heart" [J:18048]
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Allelic Composition: Pitx2tm2Sac/Pitx2+,Tbx1tm1Bem/Tbx1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL

 MP:0000281 abnormal ventricular septum morphology "abnormality in the wall between the ventricles of the heart, usually incomplete closure" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]
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Allelic Composition: Igf2rtm1Wag/Igf2rtm1Wag
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Tbx1tm1(Fgf8)Vite/Tbx1tm1(Fgf8)Vite
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm1Bld/Tbx1tm1(Fgf8)Vite
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

 MP:0000284 double outlet right ventricle "both the aorta and the pulmonary trunk originate from the right ventricle, usually in conjunction with a ventricular septal defect" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:67826]
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Allelic Composition: Tbx1tm1Dsr/Tbx1tm1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1.1Dsr/Tbx1tm1.1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Pitx2tm2Sac/Pitx2+,Tbx1tm1Bem/Tbx1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL

Allelic Composition: Gt(ROSA)26Sortm1(Tbx1/GFP)Bem/Gt(ROSA)26Sortm1(Tbx1/GFP)Bem,Tbx1tm6(cre)Bld/Tbx1+
Genetic Background: involves: 129 * C57BL/6 * SJL

Allelic Composition: Gt(ROSA)26Sortm1(Tbx1/GFP)Bem/Gt(ROSA)26Sor+,Tbx1tm1Bld/Tbx1tm6(cre)Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL

Allelic Composition: Gt(ROSA)26Sortm1(Tbx1/GFP)Bem/Gt(ROSA)26Sortm1(Tbx1/GFP)Bem,Tbx1tm1Bld/Tbx1tm6(cre)Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL

 MP:0000428 abnormal craniofacial morphology "anomalous structure or development of the face and/or cranium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Klf4tm1Khk/Klf4tm1Khk,Tg(Klf4-cre/ERT)1Wai/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA

 MP:0000438 abnormal skull morphology "anomalous structure or development of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Gsdma3Re-Den/Gsdma3Re-Den
Genetic Background: C3HeB/FeJ

 MP:0000585 kinked tail "a sharp bend or zig-zag in the tail" [J:61295]
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Allelic Composition: Tbx1tm1(Fgf8)Vite/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0000680 absent parathyroid glands "missing the two small, paired endocrine glands, usually found embedded in the connective tissue capsule on the posterior surface of the thyroid gland, which secrete parathyroid hormone (PTH) " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Gsdma3Re-Den/Gsdma3Re-Den
Genetic Background: C3HeB/FeJ

Allelic Composition: Tbx1tm1Bem/Tbx1tm1Bem
Genetic Background: FVB.Cg-Tbx1tm1Bem

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

 MP:0000704 abnormal thymus development "anomaly in the formation and/or differentiation of the thymus" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Gsdma3Re-Den/Gsdma3Re-Den
Genetic Background: C3HeB/FeJ

 MP:0000705 athymia "absence of the primary lymphoid organ" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tbx1tm1Dsr/Tbx1tm1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1.1Dsr/Tbx1tm1.1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

Allelic Composition: Tbx1tm1Bem/Tbx1tm1Bem
Genetic Background: FVB.Cg-Tbx1tm1Bem

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Tbx1tm1Bld/Tbx1tm5Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm5Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Tbx1m1Jlk/Tbx1m1Jlk
Genetic Background: 129/Sv-Tbx1m1Jlk Chrdtm1Emdr

Allelic Composition: Tbx1m1Jlk/Tbx1m1Jlk
Genetic Background: 129/Sv-Tbx1m1Jlk

Allelic Composition: Tbx1m1Jlk/Tbx1tm1Bld
Genetic Background: involves: 129/Sv

Allelic Composition: Tbx1tm1Bld/Tbx1tm2.1Bem,Tfap2atm1(cre)Moon/Tfap2a+
Genetic Background: either: (involves: 129/Sv * C57BL/6 * SJL) or (involves: 129/Sv * C57BL/6J * CBA * SJL)

 MP:0000706 small thymus "reduced size of the thymus" [J:36561, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:31167]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm3Bld,Tg(Myh6-cre)2182Mds/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Kat6atm2.2Avo/Kat6a+,Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1m1H/Tbx1m1H
Genetic Background: involves: C3H/HeH * C57BL/6J

 MP:0000729 abnormal myogenesis "anomaly in embryonic formation of muscle cells or fibers" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Myf5tm1Tajb/Myf5tm1Tajb,Pax7tm1.1Tajb/Pax7tm1.1Tajb
Genetic Background: involves: 129S2/SvPas

 MP:0001056 abnormal cranial nerve morphology "any anomaly, deformity, or malformation of any of the twelve nerves that emerge from the cranium as opposed to the spinal nerves" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:45302]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001065 abnormal trigeminal nerve morphology "malformed chief sensory nerve of the face and motor nerve of the muscles of mastication; has three major divisions: ophthalmic, maxillary and mandibular " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, Principles of Neural Science:ISBN 0-8385-8034-3, J:33038]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: involves: 129 * C57BL/6

Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001068 abnormal mandibular nerve branching "malformed or misprojected axons of the mandibular nerve" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:60159]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

 MP:0001071 abnormal facial nerve morphology "malformed or misprojection of motor axons from the pons to the face" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:29973]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: involves: 129 * C57BL/6

 MP:0001072 abnormal vestibulocochlear nerve morphology "malformed sensory nerve innervating the receptor cells of the membranous labyrinth" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:23837]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: involves: 129 * C57BL/6

 MP:0001073 abnormal glossopharyngeal nerve morphology "malformed or misprojection of sensory and autonomic axons to the parotid gland, carotid body, posterior third of the tongue" [Principles of Neural Science:ISBN 0-8385-8034-3, J:33038]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001074 abnormal vagus nerve morphology "malformed or misprojection of autonomic, sensory and motor axons of the tenth cranial nerve to the pharynx, larynx, trachea, lungs, heart and GI tract" [Principles of Neural Science:ISBN 0-8385-8034-3, J:33038]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

 MP:0001075 abnormal accessory nerve morphology "any malformation or misprojection of the 11th cranial nerve, which normally originates from neurons in the medulla and in the cervical spinal cord" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

 MP:0001096 abnormal glossopharyngeal ganglion morphology "malformed group of neuron cell bodies associated with the ninth cranial nerve" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001100 abnormal vagus ganglion morphology "malformed group of sensory neuron cell bodies associated with the vagus nerve" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001394 circling "repeated, compulsive movement in a circle; often associated with inner ear defects" [MGI:CLS, J:61295]
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Allelic Composition: Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb,Tbx1tm6(cre)Bld/Tbx1+,Tg(Pax2-cre)1Akg/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001395 bi-directional circling "circling behavior exhibited in both clockwise and counterclockwise directions" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Fkbp1atm1.1Shou/Fkbp1atm1Zuk,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL

 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
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Allelic Composition: Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb,Tbx1tm6(cre)Bld/Tbx1+,Tg(Pax2-cre)1Akg/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001429 dehydration "excessive water loss from the body or from an organ or bodily part" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:50053]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm3Bld,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL

 MP:0001575 cyanosis "a dark bluish or purple skin discoloration resulting from deficient oxygenation of the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60159]
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Allelic Composition: Pitx2tm2Sac/Pitx2+,Tbx1tm1Bem/Tbx1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL

 MP:0001614 abnormal vasculature "anomalies in the structure of development of the network of tubes that carries blood through the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Smad7Gt(YHC053)Byg/Smad7+,Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Smad7Gt(YHC053)Byg/Smad7+,Tbx1tm6(cre)Bld/Tbx1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Tbx1tm6(cre)Bld/Tbx1+
Genetic Background: involves: C57BL/6J

 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm3Bld,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL

 MP:0001785 edema "an accumulation of an excessive amount of watery fluid in cells or intercellular tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54065]
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Allelic Composition: Tbx1m1H/Tbx1m1H
Genetic Background: involves: C3H/HeH * C57BL/6J

 MP:0001786 skin edema "accumulation of an excessive amount of fluid in the skin" [J:65039]
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Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd

 MP:0001823 thymus hypoplasia "small size due to reduced cell number in the thymus" [J:23255]
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Allelic Composition: Tbx1tm1Bem/Tbx1tm1Bem
Genetic Background: FVB.Cg-Tbx1tm1Bem

Allelic Composition: Fgf8tm1.4Mrt/Fgf8+,Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * ICR

Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Tbx1tm1Bld/Tbx1tm2.1Bem,Tfap2atm1(cre)Moon/Tfap2a+
Genetic Background: either: (involves: 129/Sv * C57BL/6 * SJL) or (involves: 129/Sv * C57BL/6J * CBA * SJL)

 MP:0001850 otitis media "middle ear inflammation" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60896]
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Allelic Composition: Tbx1tm1Bem/Tbx1+
Genetic Background: FVB.Cg-Tbx1tm1Bem

 MP:0001879 abnormal lymphatic vessel morphology "malformation of the network of vessels which carries lymph around the body" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+,Tbx1tm3.1Bld/Tbx1tm6(cre)Bld
Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvEvBrd

Allelic Composition: Tbx1tm1Bld/Tbx1tm3Bld,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Tbx1tm1Bld/Tbx1tm3Bld,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL

 MP:0001953 respiratory failure "cessation of or failure to commence breathing" [MGI:cls, J:60159]
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Allelic Composition: Gsdma3Re-Den/Gsdma3Re-Den
Genetic Background: C3HeB/FeJ

 MP:0002066 abnormal motor capabilities/coordination/movement "altered ability to coordinate voluntary movement or repetitive, compulsive movements" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Clec1btm1.2Arte/Clec1btm1.2Arte
Genetic Background: involves: 129 * C57BL/6

 MP:0002082 postnatal lethality "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: H2-Ab1bm12/H2-Ab1bm12
Genetic Background: NZB.B6(C)-H2-Ab1bm12

Allelic Composition: Tbx1tm1(Fgf8)Vite/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0002102 abnormal ear morphology "structural or developmental anomaly of any of the structures involved in the ear or vestibular system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Csn3tm1Kuma/Csn3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0002116 abnormal craniofacial bone morphology "abnormal development of cranial or facial bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tbx1tm2.2Bem/Tbx1tm2.2Bem
Genetic Background: involves: 129/Sv * C57BL/6J * SJL * Swiss Webster

Allelic Composition: Tbx1tm2Bem/Tbx1tm2Bem
Genetic Background: involves: 129/Sv * C57BL/6J * SJL

 MP:0002127 abnormal cardiovascular system morphology "abnormal development of the heart or vascular tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Ripply3tm1Sjt/Ripply3tm1Sjt,Tbx1tm1Bem/Tbx1tm1Bem
Genetic Background: involves: 129/Sv * 129S1/Sv * C57BL/6J * SJL

Allelic Composition: Kat6atm1Avo/Kat6a+,Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129 * 129S7/SvEvBrd * BALB/c * C57BL/6

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm2Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1m1Jlk/Tbx1+
Genetic Background: 129/Sv-Tbx1m1Jlk

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.1Bem,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: either: (involves: 129/Sv * C57BL/6 * C57BL/6J * CBA/J * SJL) or (involves: 129/Sv * C57BL/6J * CBA/J * CD-1 * SJL)

Allelic Composition: Tbx1tm7.1Bld/Tbx1tm7.1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm8.1Bld/Tbx1tm8.1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0002177 abnormal outer ear morphology "malformation or malfunction of any components of the auricles or external acoustic meatus" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Tbx1m1Jlk/Tbx1m1Jlk
Genetic Background: 129/Sv-Tbx1m1Jlk Chrdtm1Emdr

Allelic Composition: Tbx1m1Jlk/Tbx1m1Jlk
Genetic Background: 129/Sv-Tbx1m1Jlk

Allelic Composition: Tbx1m1Jlk/Tbx1tm1Bld
Genetic Background: involves: 129/Sv

 MP:0002192 hydrops fetalis "an abnormal accumulation of serous fluid in fetal tissues" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gsdma3Re-Den/Gsdma3Re-Den
Genetic Background: C3HeB/FeJ

 MP:0002253 abnormal pharyngeal muscle morphology "structural anomaly of any of the muscles of the pharynx, the inferior, middle and superior constrictors, salpingopharyngeus, and stylopharyngeus" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Myf5tm1Tajb/Myf5tm1Tajb,Pax7tm1.1Tajb/Pax7tm1.1Tajb
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Myf5tm2Tajb/Myf5tm2Tajb,Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ

Allelic Composition: Myf5tm2Tajb/Myf5+,Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ

 MP:0002258 abnormal cricoid cartilage morphology "any structural anomaly of the most inferior of the laryngeal cartilages " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0]
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Allelic Composition: Tbx1tm1.1Dsr/Tbx1tm1.1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

 MP:0002260 abnormal thyroid cartilage morphology "any structural anomaly of the largest of the laryngeal cartilages " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: involves: 129 * C57BL/6

 MP:0002263 abnormal laryngeal muscle morphology "any structural anomaly of the muscles associated with the larynx " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Myf5tm1Tajb/Myf5tm1Tajb,Pax7tm1.1Tajb/Pax7tm1.1Tajb
Genetic Background: involves: 129S2/SvPas

 MP:0002428 abnormal semicircular canal "anomaly of the organ of balance composed of three long bony tubes of the labyrinth" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Gsdma3Re-Den/Gsdma3Re-Den
Genetic Background: C3HeB/FeJ

 MP:0002557 abnormal social/conspecific interaction "deviation of the normal behavior of mice towards each other" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Clec1btm1.2Arte/Clec1btm1.2Arte
Genetic Background: involves: 129 * C57BL/6

 MP:0002633 persistent truncus arteriosis "complete failure of the common arterial trunk opening out of both ventricles to divide into the aorta and pulmonary artery during development" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm3Bld,Tg(Myh6-cre)2182Mds/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm1Dsr/Tbx1tm1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1.1Dsr/Tbx1tm1.1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

Allelic Composition: Tbx1tm1Bem/Tbx1tm1Bem
Genetic Background: FVB.Cg-Tbx1tm1Bem

Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

Allelic Composition: Tbx1tm1(Fgf8)Vite/Tbx1tm1(Fgf8)Vite
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm1Bld/Tbx1tm1(Fgf8)Vite
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Hoxa3tm1(cre)Moon/Hoxa3+,Tbx1tm3Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Tbx1tm1Bld/Tbx1tm5Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Tbx1m1Jlk/Tbx1m1Jlk
Genetic Background: 129/Sv-Tbx1m1Jlk Chrdtm1Emdr

Allelic Composition: Tbx1m1Jlk/Tbx1m1Jlk
Genetic Background: 129/Sv-Tbx1m1Jlk

Allelic Composition: Tbx1m1Jlk/Tbx1tm1Bld
Genetic Background: involves: 129/Sv

Allelic Composition: Tbx1tm1Bld/Tbx1tm2.1Bem,Tfap2atm1(cre)Moon/Tfap2a+
Genetic Background: either: (involves: 129/Sv * C57BL/6 * SJL) or (involves: 129/Sv * C57BL/6J * CBA * SJL)

Allelic Composition: Eya1tm1Rilm/Eya1tm1Rilm,Tbx1tm1Bem/Tbx1+
Genetic Background: involves: 129 * C57BL/6 * CD-1 * SJL

Allelic Composition: Gt(ROSA)26Sortm1(Tbx1/GFP)Bem/Gt(ROSA)26Sortm1(Tbx1/GFP)Bem,Tbx1tm6(cre)Bld/Tbx1+
Genetic Background: involves: 129 * C57BL/6 * SJL

Allelic Composition: Gt(ROSA)26Sortm1(Tbx1/GFP)Bem/Gt(ROSA)26Sortm1(Tbx1/GFP)Bem,Tbx1tm1Bld/Tbx1tm6(cre)Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL

Allelic Composition: Tbx1tm1Bld/Tbx1tm6(cre)Bld
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Tbx1m1H/Tbx1m1H
Genetic Background: involves: C3H/HeH * C57BL/6J

 MP:0002639 micrognathia "abnormally reduced size of the jaws, especially of the mandible" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

 MP:0002672 abnormal branchial arch artery morphology "malformation of the vessels formed within the five pairs of branchial arches in embryogenesis; in the adult, some of these vessels give rise to the great vessels" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Nkx2-5tm1(cre)Rjs/Nkx2-5+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Bmp2tm1Brd/Bmp2+,Tbx1tm1Pa/Tbx1+
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Tbx1tm1Bld/Tbx1tm5Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1m1Jlk/Tbx1m1Jlk
Genetic Background: 129/Sv-Tbx1m1Jlk

Allelic Composition: Tbx1m1Jlk/Tbx1tm1Bld
Genetic Background: involves: 129/Sv

Allelic Composition: Smad7Gt(YHC053)Byg/Smad7+,Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0002745 abnormal atrioventricular valve morphology "malformation of the valves that gate the flow of blood from the atria into the ventricles" [J:82728, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Pitx2tm2Sac/Pitx2+,Tbx1tm1Bem/Tbx1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL

 MP:0002746 abnormal semilunar valve morphology "malformation of the valves that gate the flow of blood from the ventricles into the aorta and pulmonary trunk" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:82728]
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Allelic Composition: Tbx1tm1(Fgf8)Vite/Tbx1tm1(Fgf8)Vite
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm1Bld/Tbx1tm1(Fgf8)Vite
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0002797 thigmotaxis "preference of a mouse for the side walls of a cage or box; usually an indicator of increased anxiety response" [J:56814]
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Allelic Composition: Clec1btm1.2Arte/Clec1btm1.2Arte
Genetic Background: involves: 129 * C57BL/6

 MP:0002855 abnormal cochlear ganglion morphology "malformation, malfunction or absence of the group of nerve cell bodies that conveys auditory sensation from the organ of Corti to the hindbrain and resides on the cochlear part of the vestibulocochlear nerve (eighth cranial nerve)" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Fgfr2tm1.1Dor/Fgfr2tm1.1Dor
Genetic Background: involves: 129X1/SvJ

 MP:0002858 abnormal posterior semicircular canal "anomaly of the posterior segment of the long bony tube of the labyrinth that is involved in the sense of balance" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Chd7Whi/Chd7+,Tbx1tm1Bld/Tbx1+
Genetic Background: B6.Cg-Chd7Whi Tbx1tm1Bld

 MP:0002884 abnormal branchial arches "malformation or anomaly in the transient structures of the embryo that develop into regions of the head, neck and ears" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tfap2atm1Jae/Tfap2a+
Genetic Background: involves: 129P/Ola * 129S4/SvJae

Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: involves: 129 * C57BL/6

Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm1(Fgf8)Vite/Tbx1tm1(Fgf8)Vite
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm1Bld/Tbx1tm1(Fgf8)Vite
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

 MP:0002925 abnormal cardiovascular development "aberrant formation or incomplete differentiation of the cardiovascular system" [RGD:Rat Genome Database submission]
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Allelic Composition: Six1tm1Mair/Six1tm1Mair
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Tbx1tm1Bem/Tbx1+
Genetic Background: involves: 129 * C57BL/6 * CD-1 * SJL

Allelic Composition: Eya1tm1Rilm/Eya1+,Tbx1tm1Bem/Tbx1+
Genetic Background: involves: 129 * C57BL/6 * CD-1 * SJL

Allelic Composition: Six1tm1Mair/Six1tm1Mair,Tbx1tm1Bem/Tbx1tm1Bem
Genetic Background: involves: 129 * C57BL/6 * CD-1 * SJL

 MP:0002950 abnormal neural crest cell migration "defect in the dispersion of the transient and migratory group of cells that emerge from the dorsal region of the neural tube and migrate to many peripheral locations to form various tissues of the adult" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: involves: 129 * C57BL/6

Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm5Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

 MP:0002951 small thyroid gland "reduced size of the endocrine gland located in the front and to the sides of the upper part of the trachea, and which secretes thyroid hormone and calcitonin " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

 MP:0003007 ectopic thymus "ectopic location of the thymus primordium, which normally resides in the superior mediastinum and lower part of the neck" [ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator, J:76015]
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Allelic Composition: Chd7Gt(XK403)Byg/Chd7+,Tbx1tm1Bld/Tbx1+
Genetic Background: either: (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6) or (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CD-1)

 MP:0003048 abnormal cervical vertebrae morphology "malformation of any or all of the seven bony segments of the spine located anterior to the thoracic vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Tbx1tm1(Fgf8)Vite/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0003051 curly tail "a loop or corkscrew-like curl in the tail" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Tbx1tm1(Fgf8)Vite/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0003056 abnormal hyoid bone "anomalous structure of the U-shaped bone lying between the mandible and the larynx that supports the tongue muscles" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, hdene:Howard Dene, Mouse Genome Informatics Curator]
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Allelic Composition: Tbx1tm1.1Dsr/Tbx1tm1.1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: involves: 129 * C57BL/6

 MP:0003138 absent tympanic ring "missing the bony ring at the ear canal to which the tympanic membrane is attached" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:46972]
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Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

 MP:0003142 anotia "congenital absence of one or both auricles of the ears" [J:57313, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Tbx1tm1.1Dsr/Tbx1tm1.1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1Bem/Tbx1tm1Bem
Genetic Background: FVB.Cg-Tbx1tm1Bem

 MP:0003147 absent cochlea "absence or agenesis of the cochlea" [J:23837, J:36834, J:46972, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: involves: 129 * C57BL/6

Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Tg(Pax2-cre)1Akg/0
Genetic Background: involves: 129/Sv * C57BL/6 * SJL

 MP:0003161 absent lateral semicircular canal 
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Allelic Composition: Chd7Gt(XK403)Byg/Chd7+,Tbx1tm1Bld/Tbx1+
Genetic Background: either: (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6) or (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CD-1)

Allelic Composition: Chd7Whi/Chd7+,Tbx1tm1Bld/Tbx1+
Genetic Background: B6.Cg-Chd7Whi Tbx1tm1Bld

 MP:0003395 abnormal subclavian artery morphology "malformation of the right or left subclavian arteries, The right subclavian artery extends from the brachiocephalic artery to the right side of the body. The left subclavian artery extends from the aortic arch to the left side of the body." [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Chd7Gt(XK403)Byg/Chd7+,Tbx1tm1Bld/Tbx1+
Genetic Background: either: (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6) or (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CD-1)

 MP:0003410 abnormal artery development "anomaly in the process of forming the blood vessels that carry blood away from the heart" [J:94740, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Smad7Gt(YHC053)Byg/Smad7+,Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0003461 abnormal response to novel object "altered investigative behavior from controls in reactions associated with exposing an animal to a novel object" [CFG:Center for Functional Genomics, Northwestern University]
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Allelic Composition: Clec1btm1.2Arte/Clec1btm1.2Arte
Genetic Background: involves: 129 * C57BL/6

 MP:0003679 ear lobe hypoplasia "a decrease in the number of cells in the ear lobes" [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Tbx1tm1Bld/Tbx1tm5Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0003703 abnormal vestibulocochlear ganglion morphology "malformed group of neuron cell bodies associated with the eighth cranial nerve during embryogenesis; splits in later development to form the cochlear and vestibular ganglia" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Tg(Pax2-cre)1Akg/0
Genetic Background: involves: 129/Sv * C57BL/6 * SJL

 MP:0003743 abnormal facial morphology "anomalous structure or development of the face" [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

 MP:0003755 abnormal palate "anomaly in the roof of the mouth in vertebrates formed anteriorly by a bony projection of the upper jaw (hard palate) and posteriorly by the fold of connective tissue (soft palate) " [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: H2-Ab1bm12/H2-Ab1bm12
Genetic Background: NZB.B6(C)-H2-Ab1bm12

 MP:0003814 vascular smooth muscle cell hypoplasia "decreased numbers of smooth muscle cells in the vascular wall" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Smad7Gt(YHC053)Byg/Smad7+,Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0003874 absent branchial arches "missing the transient structures of the embryo that develop into regions of the head, neck and ears" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0003935 abnormal craniofacial development "anomaly in the process of forming the face and/or cranium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tbx1tm7.1Bld/Tbx1tm7.1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm1Bld/Tbx1tm8.1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0003938 abnormal ear development "developmental anomaly of any of the structures involved in the ear or vestibular system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Chd7Gt(XK403)Byg/Chd7+,Tbx1tm1Bld/Tbx1+
Genetic Background: either: (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6) or (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CD-1)

 MP:0004038 lymphangiectasis "dilation of the lymphatic vessels, the basic process that may result in the formation of a lymphangioma" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:71816]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd

 MP:0004113 abnormal aortic arch morphology "structural anomoly of the portion of the descending aorta proceeding from the arch of the aorta and extending to the diaphragm " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Tfap2atm1Jae/Tfap2a+
Genetic Background: involves: 129P/Ola * 129S4/SvJae

Allelic Composition: Tbx1tm1Bld/Tbx1tm3Bld,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm1Bld/Tbx1tm3Bld,Tg(Myh6-cre)2182Mds/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm1.1Dsr/Tbx1+
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Fgf8tm1.4Mrt/Fgf8+,Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * ICR

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

Allelic Composition: Tbx1tm1(Fgf8)Vite/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Fgf8tm1.4Mrt/Fgf8+,Tbx1tm4(cre/Esr1*)Bld/Tbx1+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Fgf8tm1.3Mrt/Fgf8tm1.4Mrt,Tbx1tm4(cre/Esr1*)Bld/Tbx1+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Fgf8tm1.3Mrt/Fgf8+,Tbx1tm4(cre/Esr1*)Bld/Tbx1+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Tbx1tm4(cre/Esr1*)Bld/Tbx1+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Tbx1tm1Bld/Tbx1tm5Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm1Bld/Tbx1tm2.1Bem,Tfap2atm1(cre)Moon/Tfap2a+
Genetic Background: either: (involves: 129/Sv * C57BL/6 * SJL) or (involves: 129/Sv * C57BL/6J * CBA * SJL)

 MP:0004157 interrupted aortic arch "complete discontinuation/blockage between the ascending and descending aorta; includes Type A, interruption distal to the subclavian artery that is ipsilateral to the second carotid artery, and Type B, interruption between second carotid artery and ipsilateral subclavian artery" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Clcn5tm1Gug/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Tbx1tm1Bem/Tbx1+
Genetic Background: involves: 129/Sv * C57BL/6J * SJL

Allelic Composition: Fgf8tm1.4Mrt/Fgf8+,Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * ICR

Allelic Composition: Fgf15tm1Sms/Fgf15+,Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6

Allelic Composition: Tbx1tm1(Fgf8)Vite/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Chd7Gt(XK403)Byg/Chd7+,Tbx1tm1Bld/Tbx1+
Genetic Background: either: (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6) or (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CD-1)

 MP:0004158 right aortic arch "the aortic arch lies to the right of the trachea and esophagus; results from persistance of the entire right dorsal arch and involution of a segment of the left arch" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Tbx1tm1Dsr/Tbx1tm1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1.1Dsr/Tbx1tm1.1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

Allelic Composition: Tbx1tm1Bem/Tbx1tm1Bem
Genetic Background: FVB.Cg-Tbx1tm1Bem

Allelic Composition: Fgf8tm1.4Mrt/Fgf8+,Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * ICR

 MP:0004159 double aortic arch "defect in which the main aorta tube splits into large left and right branches (right and left aortic arches), encircling the trachea and esophagus, before becoming one tube to go to the lower body " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Tbx1tm1Dsr/Tbx1tm1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1.1Dsr/Tbx1tm1.1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

Allelic Composition: Tbx1tm1(Fgf8)Vite/Tbx1tm1(Fgf8)Vite
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm1Bld/Tbx1tm1(Fgf8)Vite
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0004160 retroesophageal right subclavian artery "the subclavian artery aberrantly originates from the aortic arch distal to the origin of the left subclavian artery, i.e., it is the last branch of the aortic arch" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Hoxa13Hd/Hoxa13+
Genetic Background: involves: MYA/Hu

Allelic Composition: Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

Allelic Composition: Tbx1tm1(Fgf8)Vite/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Kat6atm2.2Avo/Kat6a+,Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0004161 cervical aortic arch "aortic arch is located above the level of the clavicle" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Hoxa13Hd/Hoxa13+
Genetic Background: involves: MYA/Hu

Allelic Composition: Fgf8tm1.4Mrt/Fgf8+,Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * ICR

Allelic Composition: Tbx1tm1(Fgf8)Vite/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0004204 absent stapes "absence of the smallest and innermost of the three auditory ossicles" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: involves: 129 * C57BL/6

 MP:0004236 absent masseter muscle "absence of the masticatory muscle of posterior cheek" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Bem/Tbx1tm1Bem
Genetic Background: FVB.Cg-Tbx1tm1Bem

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

 MP:0004238 absent pterygoid muscle "absence of either the internal or external or of both pterygoid muscles" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Bem/Tbx1tm1Bem
Genetic Background: FVB.Cg-Tbx1tm1Bem

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

 MP:0004249 abnormal crista ampullaris morphology "anomaly in the elevation found on the inner surface of the ampullae of each semicircular duct; filaments of the vestibular nerve pass through the crista to reach hair cells on its surface; the hair cells are capped by the cupula, a gelatinous protein-polysaccharide mass" [J:60193, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb,Tbx1tm6(cre)Bld/Tbx1+,Tg(Pax2-cre)1Akg/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0004310 small otic vesicle "reduced size of the simple epithelial sac formed from the otic placode that gives rise to the structures of the inner ear" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: involves: 129 * C57BL/6

Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Tg(Pax2-cre)1Akg/0
Genetic Background: involves: 129/Sv * C57BL/6 * SJL

 MP:0004311 otic vesicle hypoplasia "underdevelopment of the simple epithelial sac formed from the otic placode that gives rise to the structures of the inner ear, usually due to a reduction in cell number" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr2tm1.1Dor/Fgfr2tm1.1Dor
Genetic Background: involves: 129X1/SvJ

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Tg(Pax2-cre)1Akg/0
Genetic Background: involves: 129/Sv * C57BL/6 * SJL

 MP:0004314 absent vestibule "absence of the cavity between the semicircular canals and the cochlea of the inner ear" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: involves: 129 * C57BL/6

Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Tg(Pax2-cre)1Akg/0
Genetic Background: involves: 129/Sv * C57BL/6 * SJL

 MP:0004329 saccular degeneration "degeneration or loss of the smaller of the two sacs in the vestibule" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb,Tbx1tm6(cre)Bld/Tbx1+,Tg(Pax2-cre)1Akg/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0004332 utricular degeneration "degeneration or loss of the larger of the two sacs in the vestibule" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb,Tbx1tm6(cre)Bld/Tbx1+,Tg(Pax2-cre)1Akg/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0004424 temporal bone hypoplasia "underdevelopment or reduced size, usually due to a reduced number of cells, in the large, irregular bone located at the base and side of the skull" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

 MP:0004469 abnormal zygomatic arch morphology "any structural anomaly of the bony arch in vertebrates that extends along the side or front of the skull beneath the eye socket and is formed by the temporal process of the zygomatic bone and the zygomatic process of the temporal bone" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

 MP:0004555 pharynx hypoplasia "underdevelopment or reduced size, usually due to a reduced number of cells,of the passage between the mouth and the posterior nares and the larynx and esophagus" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Tbx1tm1Bld/Tbx1tm5Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0004568 fusion of glossopharyngeal and vagus nerve "union of the ninth and tenth cranial nerves into a single structure" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0004569 glossopharyngeal nerve hypoplasia "underdevelopment or reduced size, usually due to a reduced number of cells, of the sensory and autonomic axons to the parotid gland, carotid body, posterior third of the tongue; the branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion" [ISBN:0838580343 "Kandel ER, et al. Principles of Neural Science, 3rd edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

 MP:0004572 fusion of basioccipital and basisphenoid bone "union of the basioccipital and basisphenoid bones into one structure, when this fusion does not normally occur (such as in a species where these bones normally persist as separate entities)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Dsr/Tbx1tm1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1.1Dsr/Tbx1tm1.1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

 MP:0004599 abnormal vertebral arch morphology "any structural anomaly of the dorsal part of a vertebra, consisting of a pair of pedicles, a pair of laminae, and seven processes (four articular processes, two transverse processes, and one spinous process)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1(Fgf8)Vite/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0004607 abnormal cervical atlas morphology "any structural anomaly of the first (topmost, C1) cervical vertebra which supports the globe of the head" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

Allelic Composition: Tbx1tm1(Fgf8)Vite/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0004608 abnormal cervical axis morphology "any structural anomaly of the second cervical vertebra (C2) which forms the pivot upon which the first cervical (atlas, C1) vertebra rotates" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1(Fgf8)Vite/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0004612 fusion of vertebral bodies "improper union of the main cylindrical portion of adjacent vertebra ventral to the vertebral canal" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1(Fgf8)Vite/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0004668 absent vertebral body "absence of the main cylindrical portion of the vertebra ventral to the vertebral canal" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Tbx1tm1(Fgf8)Vite/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0004740 sensorineural hearing loss "a form of progressive hearing loss due to a lesion of the auditory division of cranial nerve VIII or the inner ear" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Tg(Pax2-cre)1Akg/0
Genetic Background: involves: 129/Sv * C57BL/6 * SJL

 MP:0004759 decreased mitotic index "decreased number of cells in G2/M phase" [Bertram_Weiss:Bayer_Schering_Pharma_AG]
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Allelic Composition: Nkx2-5tm1(cre)Rjs/Nkx2-5+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0004787 abnormal dorsal aorta morphology "any structural anomaly of the paired arterial structures of the embryo that supplies each developing somite via efferent segmental arteries; the dorsal aortae articulate with the umbilical arteries, which return mixed blood to the villi of the chorion for reoxygenation" [ISBN:0-914294-08-3 "Gray s Anatomy"]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm1Bld/Del(16Es2el-Ufd1l)217Bld
Genetic Background: involves: 129S5/SvEvBrd * 129S7/SvEvBrd * C57BL/6

 MP:0004790 absent upper incisors "missing the upper pair of long pointed teeth that are the most anterior and prominent in the jaw" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

 MP:0004900 absent zygomatic arch "absence of the bony arch that extends along the side or front of the skull beneath the eye socket and is formed by the temporal process of the zygomatic bone and the zygomatic process of the temporal bone" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

 MP:0004912 absent mandibular coronoid process "absence of the thin, flattened, triangular eminence that arises from the upper surface of the mandibular ramus (perpendicular portion)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

 MP:0004914 absent ultimobranchial body "absence of the sac-like structure emanating from the caudal-most branchial pouch of the embryo which develops into the lateral portion of the thyroid" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Bem/Tbx1tm1Bem
Genetic Background: FVB.Cg-Tbx1tm1Bem

 MP:0005105 abnormal middle ear ossicle morphology "anomalous structure or development of the three small bones of the middle ear" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Tbx1tm1Dsr/Tbx1tm1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1.1Dsr/Tbx1tm1.1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

 MP:0005106 abnormal incus morphology "structural anomaly of the middle of the three auditory ossicles" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: involves: 129 * C57BL/6

 MP:0005107 abnormal stapes morphology "structural anomaly of the smallest and innermost of the three auditory ossicles" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132]
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Allelic Composition: Tbx1tm1Dsr/Tbx1tm1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1.1Dsr/Tbx1tm1.1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

 MP:0005191 head tilt "condition in which the portion of the body containing the brain and organs of sight, hearing, taste, and smell lists to the side" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Fkbp1atm1.1Shou/Fkbp1atm1Zuk,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL

 MP:0005272 abnormal temporal bone morphology "anomalous structure of the large, irregular bone located at the base and side of the skull; consists of three parts at birth: squamous, tympanic, and petrous" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

 MP:0005294 abnormal heart ventricle morphology "structural anomaly of one or both of the two lower chambers of the heart " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Pitx2tm2Sac/Pitx2+,Tbx1tm1Bem/Tbx1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL

 MP:0005508 abnormal skeleton morphology "malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Hoxa3tm1(cre)Moon/Hoxa3+,Tbx1tm3Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Kat6atm1Avo/Kat6a+,Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129 * 129S7/SvEvBrd * BALB/c * C57BL/6

 MP:0005579 absent outer ear "missing auricles or external acoustic meatus" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:17694]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

 MP:0005595 abnormal vascular smooth muscle physiology "anomalous function of the nonstriated, involuntary muscle tissue of the blood vessels" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Smad7Gt(YHC053)Byg/Smad7+,Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0006011 abnormal endolymphatic duct morphology "any structural alteration in the small membranous canal, connecting with both saccule and utricle of the membranous labyrinth, passing through the aqueduct of vestibule, and terminating in the endolymphatic sac." [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd

 MP:0006012 dilated endolymphatic duct "an expansion in the volume of the endolymphatic duct" [smb:Susan M Bello, Mouse Genome Informatics Curator, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:67072:]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: involves: 129 * C57BL/6

 MP:0006020 reduced size of tympanic ring "smaller than average tympanic ring" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Tbx1tm1Dsr/Tbx1tm1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1.1Dsr/Tbx1tm1.1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: involves: 129 * C57BL/6

 MP:0006024 collapsed Reissner membrane "the Reissner s membrane, which normally separates the scala media from the scala vestibuli, has collapsed onto the spiral limbus and the tectorial membrane of the organ of Corti" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator, J:37461:]
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Allelic Composition: Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb,Tbx1tm6(cre)Bld/Tbx1+,Tg(Pax2-cre)1Akg/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0006031 abnormal branchial pouch morphology "malfomation or anomaly in the series of grooves that form between the branchial arches; these endodermal evaginations develop into epithelial tissues and organs" [smb:Susan M Bello, Mouse Genome Informatics Curator, Gray s Anatomy:ISBN 0-914294-08-3]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

Allelic Composition: Tbx1tm1Bem/Tbx1tm1Bem
Genetic Background: involves: 129/Sv * C57BL/6J * SJL

Allelic Composition: Ripply3tm1Sjt/Ripply3tm1Sjt,Tbx1tm1Bem/Tbx1tm1Bem
Genetic Background: involves: 129/Sv * 129S1/Sv * C57BL/6J * SJL

 MP:0006033 abnormal external auditory canal "malformation of the canal that connects the outer and middle ear" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:57313]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: involves: 129 * C57BL/6

 MP:0006042 increased apoptosis "greater than normal programmed cell death" [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd

 MP:0006089 abnormal saccule morphology "malformation in the smaller of the two sacs in the vestibule" [smb:Susan M Bello, Mouse Genome Informatics Curator, Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99, J:92940]
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Allelic Composition: Gt(ROSA)26Sortm1(Tbx1/GFP)Bem/Gt(ROSA)26Sor+,Tbx1tm1Bld/Tbx1tm6(cre)Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL

 MP:0006107 abnormal atrioventricular canal morphology "malformation or anomaly in development of the common canal connecting the primordial atrium and ventricle" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93610]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Pitx2tm2Sac/Pitx2+,Tbx1tm1Bem/Tbx1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL

 MP:0006126 abnormal outflow tract development "anomaly in the development of the common arterial trunk that forms the aorta and pulmonary artery" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Tbx1tm1Bem/Tbx1+
Genetic Background: FVB.Cg-Tbx1tm1Bem

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Tbx1tm1Bld/Tbx1tm2.1Bem,Tfap2atm1(cre)Moon/Tfap2a+
Genetic Background: either: (involves: 129/Sv * C57BL/6 * SJL) or (involves: 129/Sv * C57BL/6J * CBA * SJL)

 MP:0006285 absent inner ear "absence of all components of the labyrinth, including the semicircular canals, vestibule and cochlea" [J:86619, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Tg(Pax2-cre)1Akg/0
Genetic Background: involves: 129/Sv * C57BL/6 * SJL

 MP:0006286 inner ear hypoplasia "underdevelopment or reduced size of inner ear structures, usually due to decreased cell number" [J:83662, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: involves: 129 * C57BL/6

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Tg(Pax2-cre)1Akg/0
Genetic Background: involves: 129/Sv * C57BL/6 * SJL

 MP:0006289 otic capsule hypoplasia "underdevelopment or reduced size, usually due to a reduced number of cells, of the cartilage or bony capsule surrounding the inner ear mechanism" [J:100584, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

 MP:0006301 abnormal mesenchyme morphology "abnormality in the loosely packed, unspecialized cells that derive mostly from the mesoderm and contribute to connective tissue, bone, cartilage and circulatory and lymphatic systems." [J:120305, mnk:Michelle Knowlton_MGI Curator]
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Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

 MP:0006339 abnormal third branchial arch morphology "anomaly in the structure of the third are which contributes to the development of the hyoid bone, stylopharyngeus muscle, inferior parathyroid gland, and thymus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

Allelic Composition: Tbx1tm1Bld/Tbx1tm5Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0006340 abnormal fourth branchial arch morphology "anomaly in the structure of the fourth arch which contributes to development of the cartilage of the larynx, laryngeal, pharyngeal, and soft palate muscles, superior parathyroid gland, and C-cells of the thymus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", zillmusom:http://musom.marshall.edu/anatomy/grosshom/z_devbranc.html]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

Allelic Composition: Tbx1tm1Bem/Tbx1+
Genetic Background: involves: 129/Sv * C57BL/6J * SJL

Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Tbx1tm1Bld/Tbx1tm5Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Ripply3tm1Sjt/Ripply3+,Tbx1tm1Bem/Tbx1+
Genetic Background: involves: 129/Sv * 129S1/Sv * C57BL/6J * SJL

 MP:0006344 small second branchial arch "reduced size of the second branchial arch" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm1Bld/Tbx1tm5Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm1Bld/Del(16Es2el-Ufd1l)217Bld
Genetic Background: involves: 129S7/SvEvBrd

 MP:0006345 absent second branchial arch "missing the second branchial arch" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: involves: 129 * C57BL/6

 MP:0006346 small branchial arch "reduced size of one or more of the branchial arches" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Bem/Tbx1+
Genetic Background: involves: 129/Sv * C57BL/6J * SJL

Allelic Composition: Ripply3tm1Sjt/Ripply3+,Tbx1tm1Bem/Tbx1+
Genetic Background: involves: 129/Sv * 129S1/Sv * C57BL/6J * SJL

 MP:0006347 abnormal sixth branchial arch morphology "anomaly in the structure of the sixth arch which contributes to the development of the sternocleidomastoid and trapezius muscles" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", zillmusom:http://musom.marshall.edu/anatomy/grosshom/z_devbranc.html]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm5Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0006354 abnormal fourth branchial arch artery morphology "any structural anomaly of the vessels formed within the fourth pair of branchial arches in embryogenesis" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

Allelic Composition: Tbx1tm1Pa/Tbx1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * Swiss Webster

Allelic Composition: Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Fgf8tm1.4Mrt/Fgf8+,Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * ICR

Allelic Composition: Tbx1tm1Bld/Del(16Es2el-Ufd1l)217Bld
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Smad7Gt(YHC053)Byg/Smad7+,Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0006355 abnormal sixth branchial arch artery morphology "any structural anomaly of the vessels formed within the sixth pair of branchial arches in embryogenesis" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Bld/Del(16Es2el-Ufd1l)217Bld
Genetic Background: involves: 129S7/SvEvBrd

 MP:0006356 abnormal third branchial arch artery morphology "any structural anomaly of the vessels formed within the third pair of branchial arches in embryogenesis" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Bld/Del(16Es2el-Ufd1l)217Bld
Genetic Background: involves: 129S7/SvEvBrd

 MP:0008428 abnormal spatial working memory "anomaly in the ability to spontaneously process spatial location information in order to naviagate or perform other behavior using such locational cues, without previous encounters or training at that location" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Clec1btm1.2Arte/Clec1btm1.2Arte
Genetic Background: involves: 129 * C57BL/6

 MP:0008778 lymphangiogenesis "any anomaly in the formation of lymphatic vessels from pre-existing lymphatic vessels" [MESH:G07.574.500.325.377.500]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Tbx1tm1Bld/Tbx1tm3Bld,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Tbx1tm1Bld/Tbx1tm3Bld,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL

 MP:0009142 decreased prepulse inhibition "decrease in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Fyntm1Fam/Fyntm1Fam
Genetic Background: involves: C57BL/6

 MP:0009879 abnormal arcus anterior morphology "any structural anomaly in the arch that connects the lateral masses of the atlas anteriorly and articulates with the anterior articular facet of the dens of the axis" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1(Fgf8)Vite/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0009887 abnormal palatal shelf fusion at midline "any anomaly in the process in which the palatal shelves grow toward the midline and adhere along the medial edge epithelia, forming the midline epithelial seam which disappears in later stages" [PMID:16942766]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd

 MP:0009888 palatal shelves fail to meet at midline "polarized growth towards the midline following palatal shelf elevation does not occur" [PMID:16942766]
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Allelic Composition: Tbx1tm1.1Dsr/Tbx1tm1.1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1Bem/Tbx1tm1Bem
Genetic Background: FVB.Cg-Tbx1tm1Bem

 MP:0009890 cleft secondary palate "congenital fissure of the tissues normally uniting to form the secondary palate" [PMID:16680722]
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Allelic Composition: Tbx1tm1.1Dsr/Tbx1tm1.1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

 MP:0009899 hyoid bone hypoplasia "underdevelopment of the hyoid bone, usually due to a deficiency in the number of cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

 MP:0009937 abnormal neuron differentiation "abnormal growth or development of the cells of the nervous system that receive, conduct, and transmit impulses" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr2tm1.1Dor/Fgfr2tm1.1Dor
Genetic Background: involves: 129X1/SvJ

Allelic Composition: Tbx1tm1Bem/Tbx1tm1Bem
Genetic Background: involves: 129/Sv * C57BL/6J * FVB * SJL

 MP:0010241 abnormal aortic arch development "anomaly in the process of forming the convex portion of the aorta between the ascending and descending parts of the aorta; including formation of the brachiocephalic trunk, the left common carotid artery, and the left subclavian artery; the brachiocephalic trunk further splits to form the right subclavian artery and the right common carotid artery" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Fgf8tm1.4Mrt/Fgf8+,Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * ICR

Allelic Composition: Fgf15tm1Sms/Fgf15+,Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6

 MP:0010326 malleus hypoplasia "underdevelopment or reduced size, usually due to a reduced number of cells, of the largest of the three auditory ossicles, which resembles a club or hammer" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: involves: 129 * C57BL/6

 MP:0010328 thin malleus neck "smaller diameter of the narrow contracted section of the malleus located between the head and the manubrium" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: involves: 129 * C57BL/6

 MP:0010356 abnormal second branchial arch artery morphology "any structural anomaly of the vessels formed within the second pair of branchial arches in embryogenesis" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Bld/Del(16Es2el-Ufd1l)217Bld
Genetic Background: involves: 129S5/SvEvBrd * 129S7/SvEvBrd * C57BL/6

 MP:0010402 ventricular septal defect "abnormal communications between the two lower chambers of the heart, including such defects in the perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular regions" [MESH:C14.240.400.560.540]
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Allelic Composition: Tfap2atm1Jae/Tfap2a+
Genetic Background: involves: 129P/Ola * 129S4/SvJae

Allelic Composition: Tbx1tm1Dsr/Tbx1tm1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1.1Dsr/Tbx1tm1.1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

Allelic Composition: Tbx1tm1Bld/Tbx1tm5Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Pitx2tm2Sac/Pitx2+,Tbx1tm1Bem/Tbx1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL

Allelic Composition: Tbx1tm1Bld/Tbx1tm2.1Bem,Tfap2atm1(cre)Moon/Tfap2a+
Genetic Background: either: (involves: 129/Sv * C57BL/6 * SJL) or (involves: 129/Sv * C57BL/6J * CBA * SJL)

Allelic Composition: Kat6atm2.2Avo/Kat6a+,Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Gt(ROSA)26Sortm1(Tbx1/GFP)Bem/Gt(ROSA)26Sortm1(Tbx1/GFP)Bem,Tbx1tm6(cre)Bld/Tbx1+
Genetic Background: involves: 129 * C57BL/6 * SJL

Allelic Composition: Gt(ROSA)26Sortm1(Tbx1/GFP)Bem/Gt(ROSA)26Sor+,Tbx1tm1Bld/Tbx1tm6(cre)Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL

Allelic Composition: Gt(ROSA)26Sortm1(Tbx1/GFP)Bem/Gt(ROSA)26Sortm1(Tbx1/GFP)Bem,Tbx1tm1Bld/Tbx1tm6(cre)Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL

Allelic Composition: Tbx1tm1Bld/Tbx1tm6(cre)Bld
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Tbx1m1H/Tbx1m1H
Genetic Background: involves: C3H/HeH * C57BL/6J

 MP:0010403 atrial septal defect "abnormal communications between the two upper chambers of the heart, including such defects in any or all of the ostium primum, ostium secundum, sinus venosus, and coronary sinus regions" [MESH:C14.240.400.560.375]
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Allelic Composition: Pitx2tm2Sac/Pitx2+,Tbx1tm1Bem/Tbx1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL

 MP:0010418 perimembraneous ventricular septal defect "abnormal communications between the two lower chambers of the heart, occurring in the membranous septum with defects in the adjacent muscular portion of the septum; it is generally located in the LV outflow tract just below the aortic valve, associated with pouches or aneurysms of the septal leaflet of the tricuspid valve, which may partially or completely close the defect; an LV-to-RA shunt may also be associated with this defect" [http://emedicine.medscape.com]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Fgf15tm1Sms/Fgf15+,Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6

 MP:0010420 muscular ventricular septal defect "abnormal communications between the two lower chambers of the heart, involving the muscular septum and often occurring as multiple communications, and includes central muscular or midmuscular, apical, or marginal communications when the defect is along the RV-septal junction; any single defect observed from the LV aspect may have several openings on the RV aspect" [http://emedicine.medscape.com]
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Allelic Composition: Fgf15tm1Sms/Fgf15+,Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6

 MP:0010425 abnormal heart and great vessel attachment "any anomaly in the in the position or pattern of the connection site of the heart to any of the primary vessels, including the superior vena cavae, inferior vena cavae, pulmonary artery, pulmonary veins, and aorta" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Pitx2tm2Sac/Pitx2+,Tbx1tm1Bem/Tbx1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL

 MP:0010440 anomalous pulmonary venous connection "abnormal development and attachment of the four pulmonary veins that normally attach to the left atrium of the heart, resulting in either partial or complete anomalous drainage back into the systemic venous circulation via an anomalous connection to the right atrium, the superior or inferior vena cava, the innominate vein, the coronary sinus or the left subclavian artery" [http://emedicine.medscape.com]
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Allelic Composition: Pitx2tm2Sac/Pitx2+,Tbx1tm1Bem/Tbx1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL

 MP:0010454 abnormal truncus arteriosis septation "anomaly in the process of dividing the common arterial trunk arising out of both heart ventricles to divide into the aorta and pulmonary artery during development" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0010459 supravalvar pulmonary trunk stenosis "diffuse constriction or narrowing of the pulmonary trunk distal to the pulmonary valve" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Pitx2tm2Sac/Pitx2+,Tbx1tm1Bem/Tbx1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL

 MP:0010465 aberrant origin of the right subclavian artery "the right subclavian artery arises from an atypical location on the aortic arch or the proximal descending aorta" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Clcn5tm1Gug/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Tbx1tm1Dsr/Tbx1tm1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1.1Dsr/Tbx1tm1.1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1Bem/Tbx1+
Genetic Background: involves: 129/Sv * C57BL/6J * SJL

Allelic Composition: Fgf15tm1Sms/Fgf15+,Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6

Allelic Composition: Tbx1tm1Bld/Tbx1tm2.1Bem,Tfap2atm1(cre)Moon/Tfap2a+
Genetic Background: either: (involves: 129/Sv * C57BL/6 * SJL) or (involves: 129/Sv * C57BL/6J * CBA * SJL)

 MP:0010551 abnormal coronary vessel morphology "any structural anomaly of any of the arteries or veins that supply blood to the heart or return blood from the heart muscles to the circulation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Pitx2tm2Sac/Pitx2+,Tbx1tm1Bem/Tbx1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL

 MP:0010583 abnormal conotruncus morphology "any structural anomaly of the distal portion of the bulbus cordis that will give rise to the conus cordis, which will give rise to the outflow regions of the ventricles, and the truncus arteriosus which will be divided into proximal ends of the ascending aorta and pulmonary trunk" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0010584 abnormal conotruncus septation "anomaly in the process in which the conotruncus separates into the conus cordis, which will give rise to the outflow regions of the ventricles, and the truncus arteriosus which will be divided into proximal ends of the ascending aorta and pulmonary trunk" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0010607 common atrioventricular valve "the presence of a single atrioventricular valve instead of both a mitral and tricuspid valve, most commonly due to incomplete or failure of fetal atrioventricular canal septation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Pitx2tm2Sac/Pitx2+,Tbx1tm1Bem/Tbx1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL

 MP:0010642 absent third branchial arch "absence of the structure of the third are which contributes to the development of the hyoid bone, stylopharyngeus muscle, inferior parathyroid gland, and thymus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: involves: 129 * C57BL/6

Allelic Composition: Tbx1tm1Bld/Del(16Es2el-Ufd1l)217Bld
Genetic Background: involves: 129S5/SvEvBrd * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

 MP:0010643 absent fourth branchial arch "absence of the structure of the fourth arch which contributes to development of the cartilage of the larynx, laryngeal, pharyngeal, and soft palate muscles, superior parathyroid gland, and C-cells of the thymus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Bld/Del(16Es2el-Ufd1l)217Bld
Genetic Background: involves: 129S5/SvEvBrd * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm5Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

 MP:0010644 absent sixth branchial arch "absence of the structure of the sixth arch which contributes to the development of the sternocleidomastoid and trapezius muscles" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Bld/Del(16Es2el-Ufd1l)217Bld
Genetic Background: involves: 129S5/SvEvBrd * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

 MP:0010729 absent arcus anterior "absence of the arch that connects the lateral masses of the atlas anteriorly and articulates with the anterior articular facet of the dens of the axis" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm3Bld,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL

Allelic Composition: Gt(ROSA)26Sortm1(Tbx1/GFP)Bem/Gt(ROSA)26Sortm1(Tbx1/GFP)Bem,Tbx1tm6(cre)Bld/Tbx1+
Genetic Background: involves: 129 * C57BL/6 * SJL

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
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Allelic Composition: Tbx1tm1Dsr/Tbx1tm1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1.1Dsr/Tbx1tm1.1Dsr
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

Allelic Composition: Tbx1tm2.2Bem/Tbx1tm2.2Bem
Genetic Background: involves: 129/Sv * C57BL/6J * SJL * Swiss Webster

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

Allelic Composition: Pitx2tm2Sac/Pitx2+,Tbx1tm1Bem/Tbx1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL

 MP:0011088 partial neonatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith]
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Allelic Composition: Clcn5tm1Gug/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Tbx1tm1.1Dsr/Tbx1+
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Kat6atm1Avo/Kat6a+,Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129 * 129S7/SvEvBrd * BALB/c * C57BL/6

 MP:0011659 interrupted aortic arch, type b "complete discontinuation/blockage between the ascending and descending aorta with the interruption located between second carotid artery and ipsilateral subclavian artery" [MGI:csmith]
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Allelic Composition: Kat6atm2.2Avo/Kat6a+,Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0011967 increased or absent threshold for auditory brainstem response "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith]
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Allelic Composition: Tbx1tm1Bem/Tbx1+
Genetic Background: FVB.Cg-Tbx1tm1Bem

Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Tg(Pax2-cre)1Akg/0
Genetic Background: involves: 129/Sv * C57BL/6 * SJL

 MP:0012080 chylous ascites "the extravasation of milky triglyceride-rich chyle into the peritoneal cavity; often a secondary symptom of neoplasms" [MGI:csmith]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm3Bld,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL

 MP:0012493 absent branchial arch arteries "absence of the vessels formed within the six (five in mammals) pairs of branchial arches in embryogenesis; in the adult, some of these vessels give rise to the great vessels" [MGI:anna]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1(Fgf8)Vite
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0012721 short neck "decreased length of the neck" [MGI:anna]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

 MP:0012752 abnormal cardiac neural crest cell migration "any anomaly in the migratory path of cardiac neural crest cells (NCCs), a subpopulation of cranial NCCs which originate from the lower hindbrain between the otic placode and third somite and migrate to the circumpharyngeal ridge (an arc-shape ridge located dorsal to the forming caudal pharyngeal arches) and then into the 3rd, 4th and 6th pharyngeal arches and the cardiac outflow tract (OFT); cardiac NCCs undergo migration away from the neural tube by following a dorsolateral path under the ectoderm, leading them to the pharyngeal arches; after pausing, they resume migration under the pharyngeal endoderm and, along the aortic arch arteries, populate the cardiac OFT where they contribute the aorticopulmonary septum, and ultimately colonize the heart to form the ventricular septum and cardiac ganglia" [MGI:anna]
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Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

 MP:0012757 abnormal cranial neural crest cell migration "any anomaly in the migratory path of the cranial neural crest cells (NCCs), which originate in the anterior part of the developing embryo and reside between the mid-diencephalon and the forming hindbrain; cranial NCCs migrate dorsolaterally to form the craniofacial mesenchyme that differentiates into various craniofacial cartilages and bones, cranial neurons, glia, and connective tissues of the face; these cells enter the pharyngeal pouches and arches where they give rise to thymic cells, bones of the middle ear and jaw (mandible), and the odontoblasts of the tooth primordial; like their counterparts in the trunk, cranial NCCs contribute to the developing peripheral nervous system, along with the pigmented cell (i.e. melanocyte) lineage" [MGI:anna]
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Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

 MP:0013174 pharynx stenosis "abnormal narrowing or constriction of the passage between the mouth and the posterior nares and the larynx and esophagus" [MGI:anna]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

 MP:0013265 abnormal fourth pharyngeal pouch morphology "any structural anomaly of the fourth endodermal branchial pouch located between the fourth and sixth branchial arches (a fifth arch never establishes itself in amniotes); in most mammals, excluding rodents, the dorsal part of each fourth pouch develops into a superior parathyroid gland (parathyroid IV), which lies on the dorsal surface of the thyroid gland (the parathyroid glands derived from the third pouches descend with the thymus and are carried to a more inferior position than the parathyroid glands that are derived from the fourth pouches); the elongated ventral part of each fourth pouch develops into the ultimopharyngeal body, which fuses with the thyroid gland, giving rise to the calcitonin-producing parafollicular or C-cells of the thyroid gland" [MGI:anna, PMID:20144910]
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Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

 MP:0013268 second pharyngeal arch hypoplasia "underdevelopment or reduced size of the second pharyngeal arch, usually due to reduced cell number" [MGI:anna]
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Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

 MP:0013270 fourth pharyngeal arch hypoplasia "underdevelopment or reduced size of the fourth pharyngeal arch, usually due to reduced cell number" [MGI:anna]
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Allelic Composition: Tbx1tm1(Fgf8)Vite/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0020351 decreased vocalization "decrease in the production of vocal sound" [ORCID: orcid.org/0000-0003-4606-0597, PMID:26621702]
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Allelic Composition: Clec1btm1.2Arte/Clec1btm1.2Arte
Genetic Background: involves: 129 * C57BL/6

 MP:0030040 absent facial muscle "absence of any of the striated skeletal muscles innervated by the facial nerve (cranial nerve VII) that, among other things, control facial expression; facial muscles are derived from the second branchial/pharyngeal arch" [MGI:anna]
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Allelic Composition: Tbx1tm2.2Bem/Tbx1tm2.2Bem
Genetic Background: involves: 129/Sv * C57BL/6J * SJL * Swiss Webster

 MP:0030137 abnormal upper incisor morphology "any structural anomaly of the upper set of long teeth that are the most anterior and prominent in the jaw" [MGI:anna]
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Allelic Composition: Tbx1tm1Pa/Tbx1tm1Pa
Genetic Background: either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster)

 MP:0030228 absent tubotympanic recess "absence of the elongate recess derived from the first pharyngeal pouch; its distal part contributes to the formation of the tympanic membrane, its proximal part elongates to form the auditory tube, and its cavity gives rise to the tympanic cavity and mastoid antrum" [http://medicine.academic.ru/156417/tubotympanic_recess, MGI:anna]
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Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster

 MP:0030334 absent sixth pharyngeal arch artery "failure to develop or absence of the sixth pharyngeal arch artery" [MGI:anna]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm1Bld/Del(16Es2el-Ufd1l)217Bld
Genetic Background: involves: 129S5/SvEvBrd * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Tbx1tm1Bld/Tbx1tm5Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0030335 absent third pharyngeal arch artery "failure to develop or absence of the third pharyngeal arch artery" [MGI:anna]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm1Bld/Del(16Es2el-Ufd1l)217Bld
Genetic Background: involves: 129S5/SvEvBrd * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Tbx1tm1Bld/Tbx1tm5Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0030340 absent fourth pharyngeal arch artery "failure to develop or absence of the fourth pharyngeal arch artery" [MGI:anna]
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Allelic Composition: Nkx2-5tm1(cre)Rjs/Nkx2-5+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm1Bld/Tbx1tm1Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm1Bld/Del(16Es2el-Ufd1l)217Bld
Genetic Background: involves: 129S5/SvEvBrd * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Tbx1tm1Bld/Tbx1tm5Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Tbx1tm1Bld/Tbx1tm5Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Chd7Gt(XK403)Byg/Chd7+,Tbx1tm1Bld/Tbx1+
Genetic Background: either: (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6) or (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CD-1)

 MP:0030341 fourth pharyngeal arch artery hypoplasia "underdevelopment or reduced size of the fourth pharyngeal arch artery, usually due to a reduced number of cells" [MGI:anna]
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Allelic Composition: Nkx2-5tm1(cre)Rjs/Nkx2-5+,Tbx1tm1Bld/Tbx1tm3Bld
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm1Bld/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm1(Fgf8)Vite/Tbx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tbx1tm2.1Bem/Tbx1+,Tfap2atm1(cre)Moon/Tfap2a+
Genetic Background: either: (involves: 129/Sv * C57BL/6 * C57BL/6J * SJL) or (involves: 129/Sv * C57BL/6J * CBA * SJL)

 MP:0030535 abnormal hypoglossal cord morphology "any structural anomaly of the condensed mesenchymal band formed as migratory myoblasts arising from the myotomes of the occipital somites coalesce beside somite four and extend ventrally as an elongated column; the hypoglossal cord eventually becomes located ventral to the caudal region of the pharynx; most of the myoblasts of the hypoglossal cord remain ventral and shift cranially to form the intrinsic and extrinsic tongue muscles; some of these myoblasts shift dorsally to form the intrinsic laryngeal muscles" [https://books.google.com/books?isbn=1455727911]
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Allelic Composition: Myf5tm1Tajb/Myf5tm1Tajb,Pax7tm1.1Tajb/Pax7tm1.1Tajb
Genetic Background: involves: 129S2/SvPas

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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