ENSMUSG00000028057


Mus musculus

Features
Gene ID: ENSMUSG00000028057
  
Biological name :Rit1
  
Synonyms : GTP-binding protein Rit1 / P70426 / Rit1
  
Possible biological names infered from orthology : Q92963 / Ras like without CAAX 1
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: F1
Gene start: 88716838
Gene end: 88731049
  
Corresponding Affymetrix probe sets: 10493309 (MoGene1.0st)   1420540_a_at (Mouse Genome 430 2.0 Array)   1428710_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000029692
Ensembl peptide - ENSMUSP00000127206
Ensembl peptide - ENSMUSP00000130464
Ensembl peptide - ENSMUSP00000131384
Ensembl peptide - ENSMUSP00000125858
NCBI entrez gene - 19769     See in Manteia.
MGI - MGI:108053
RefSeq - XM_017319506
RefSeq - NM_001163310
RefSeq - NM_009069
RefSeq - XM_006501158
RefSeq - XM_006501160
RefSeq Peptide - NP_001156782
RefSeq Peptide - NP_033095
swissprot - G5E8W6
swissprot - E9Q672
swissprot - P70426
swissprot - G3UWE0
swissprot - E9Q3Z0
Ensembl - ENSMUSG00000028057
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rit1ENSDARG00000069150Danio rerio
 RIT1ENSGALG00000014647Gallus gallus
 RIT1ENSG00000143622Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rit2 / P70425 / GTP-binding protein Rit2 / Q99578* / Ras like without CAAX 2*ENSMUSG0000005745563
Rap1b / Q99JI6 / RAS related protein 1b / P61224* / RAP1B, member of RAS oncogene family*ENSMUSG0000005268141
Rap1a / P62835 / RAS-related protein 1a / P62834* / RAP1A, member of RAS oncogene family*ENSMUSG0000006879840
Rap2b / P61226 / RAP2B, member of RAS oncogene family / P61225*ENSMUSG0000003689438
Rap2a / Q80ZJ1 / Ras-related protein Rap-2a / P10114* / RAP2A, member of RAS oncogene family*ENSMUSG0000005161538
Rap2c / Q8BU31 / Ras-related protein Rap-2c / Q9Y3L5* / RAP2C, member of RAS oncogene family*ENSMUSG0000005002937
Gm266ENSMUSG0000001052932
Rasd2 / P63032 / GTP-binding protein Rhes / Q96D21* / RASD family member 2*ENSMUSG0000003447231
Rasd1 / O35626 / Dexamethasone-induced Ras-related protein 1 / Q9Y272* / ras related dexamethasone induced 1*ENSMUSG0000004989231
Diras2 / Q5PR73 / GTP-binding protein Di-Ras2 / Q96HU8* / DIRAS family GTPase 2*ENSMUSG0000004784231
Diras1 / Q91Z61 / GTP-binding protein Di-Ras1 / O95057* / DIRAS family GTPase 1*ENSMUSG0000004367029
Q5SSG5 / Rasl10b / Ras-like protein family member 10B / Q96S79* / RAS like family 10 member B*ENSMUSG0000002068425
Q8K5A4 / Rasl10a / Ras-like protein family member 10A / Q92737* / RAS like family 10 member A*ENSMUSG0000003420922


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR020849  Small GTPase superfamily, Ras-type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007265 Ras protein signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0008406 increased cellular sensitivity to hydrogen peroxide "greater incidence of cell death following exposure to hydrogen peroxide" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Kmt2atm1.1Mlc/Kmt2atm1.1Mlc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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