ENSMUSG00000057455


Mus musculus

Features
Gene ID: ENSMUSG00000057455
  
Biological name :Rit2
  
Synonyms : GTP-binding protein Rit2 / P70425 / Rit2
  
Possible biological names infered from orthology : Q99578 / Ras like without CAAX 2
  
Species: Mus musculus
  
Chr. number: 18
Strand: -1
Band: B1
Gene start: 30973489
Gene end: 31317290
  
Corresponding Affymetrix probe sets: 10457929 (MoGene1.0st)   1421779_at (Mouse Genome 430 2.0 Array)   1448125_at (Mouse Genome 430 2.0 Array)   1460166_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000122938
Ensembl peptide - ENSMUSP00000080724
Ensembl peptide - ENSMUSP00000114323
NCBI entrez gene - 19762     See in Manteia.
MGI - MGI:108054
RefSeq - NM_009065
RefSeq Peptide - NP_033091
swissprot - P70425
swissprot - F2Z432
swissprot - F8WGU6
Ensembl - ENSMUSG00000057455
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RIT2ENSGALG00000033353Gallus gallus
 RIT2ENSG00000152214Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rit1 / P70426 / GTP-binding protein Rit1 / Q92963* / Ras like without CAAX 1*ENSMUSG0000002805763
Rap1a / P62835 / RAS-related protein 1a / P62834* / RAP1A, member of RAS oncogene family*ENSMUSG0000006879842
Rap1b / Q99JI6 / RAS related protein 1b / P61224* / RAP1B, member of RAS oncogene family*ENSMUSG0000005268141
Rap2b / P61226 / RAP2B, member of RAS oncogene family / P61225*ENSMUSG0000003689436
Rap2c / Q8BU31 / Ras-related protein Rap-2c / Q9Y3L5* / RAP2C, member of RAS oncogene family*ENSMUSG0000005002936
Rap2a / Q80ZJ1 / Ras-related protein Rap-2a / P10114* / RAP2A, member of RAS oncogene family*ENSMUSG0000005161536
Diras1 / Q91Z61 / GTP-binding protein Di-Ras1 / O95057* / DIRAS family GTPase 1*ENSMUSG0000004367032
Rasd2 / P63032 / GTP-binding protein Rhes / Q96D21* / RASD family member 2*ENSMUSG0000003447232
Rasd1 / O35626 / Dexamethasone-induced Ras-related protein 1 / Q9Y272* / ras related dexamethasone induced 1*ENSMUSG0000004989232
Diras2 / Q5PR73 / GTP-binding protein Di-Ras2 / Q96HU8* / DIRAS family GTPase 2*ENSMUSG0000004784232
Gm266ENSMUSG0000001052930
Q5SSG5 / Rasl10b / Ras-like protein family member 10B / Q96S79* / RAS like family 10 member B*ENSMUSG0000002068424
Q8K5A4 / Rasl10a / Ras-like protein family member 10A / Q92737* / RAS like family 10 member A*ENSMUSG0000003420921


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR020849  Small GTPase superfamily, Ras-type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001932 regulation of protein phosphorylation IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007265 Ras protein signal transduction IGI
 biological_processGO:0010976 positive regulation of neuron projection development IEA
 biological_processGO:0010977 negative regulation of neuron projection development IGI
 biological_processGO:0030100 regulation of endocytosis IEA
 biological_processGO:0032489 regulation of Cdc42 protein signal transduction IDA
 biological_processGO:0032507 maintenance of protein location in cell IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043410 positive regulation of MAPK cascade IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IGI
 biological_processGO:0050848 regulation of calcium-mediated signaling IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0044297 cell body IDA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0097447 dendritic tree IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003682 chromatin binding IGI
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005516 calmodulin binding IPI
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0030215 semaphorin receptor binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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