ENSMUSG00000051615


Mus musculus

Features
Gene ID: ENSMUSG00000051615
  
Biological name :Rap2a
  
Synonyms : Q80ZJ1 / Rap2a / Ras-related protein Rap-2a
  
Possible biological names infered from orthology : P10114 / RAP2A, member of RAS oncogene family
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: E4
Gene start: 120478444
Gene end: 120507194
  
Corresponding Affymetrix probe sets: 10417065 (MoGene1.0st)   1421574_at (Mouse Genome 430 2.0 Array)   1426965_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000056433
NCBI entrez gene - 76108     See in Manteia.
MGI - MGI:97855
RefSeq - NM_029519
RefSeq Peptide - NP_083795
swissprot - Q80ZJ1
Ensembl - ENSMUSG00000051615
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RAP2AENSGALG00000016889Gallus gallus
 RAP2AENSG00000125249Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rap2b / P61226 / RAP2B, member of RAS oncogene family / P61225*ENSMUSG0000003689491
Rap2c / Q8BU31 / Ras-related protein Rap-2c / Q9Y3L5* / RAP2C, member of RAS oncogene family*ENSMUSG0000005002991
Rap1a / P62835 / RAS-related protein 1a / P62834* / RAP1A, member of RAS oncogene family*ENSMUSG0000006879862
Rap1b / Q99JI6 / RAS related protein 1b / P61224* / RAP1B, member of RAS oncogene family*ENSMUSG0000005268161
Diras2 / Q5PR73 / GTP-binding protein Di-Ras2 / Q96HU8* / DIRAS family GTPase 2*ENSMUSG0000004784246
Gm266ENSMUSG0000001052945
Diras1 / Q91Z61 / GTP-binding protein Di-Ras1 / O95057* / DIRAS family GTPase 1*ENSMUSG0000004367045
Rit1 / P70426 / GTP-binding protein Rit1 / Q92963* / Ras like without CAAX 1*ENSMUSG0000002805745
Rit2 / P70425 / GTP-binding protein Rit2 / Q99578* / Ras like without CAAX 2*ENSMUSG0000005745543
Rasd2 / P63032 / GTP-binding protein Rhes / Q96D21* / RASD family member 2*ENSMUSG0000003447238
Rasd1 / O35626 / Dexamethasone-induced Ras-related protein 1 / Q9Y272* / ras related dexamethasone induced 1*ENSMUSG0000004989238
Q5SSG5 / Rasl10b / Ras-like protein family member 10B / Q96S79* / RAS like family 10 member B*ENSMUSG0000002068431
Q8K5A4 / Rasl10a / Ras-like protein family member 10A / Q92737* / RAS like family 10 member A*ENSMUSG0000003420930


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR020849  Small GTPase superfamily, Ras-type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0030033 microvillus assembly IEA
 biological_processGO:0030336 negative regulation of cell migration IDA
 biological_processGO:0031532 actin cytoskeleton reorganization IEA
 biological_processGO:0031954 positive regulation of protein autophosphorylation IEA
 biological_processGO:0032486 Rap protein signal transduction IDA
 biological_processGO:0034613 cellular protein localization IEA
 biological_processGO:0035690 cellular response to drug IEA
 biological_processGO:0045184 establishment of protein localization IEA
 biological_processGO:0046328 regulation of JNK cascade IEA
 biological_processGO:0048814 regulation of dendrite morphogenesis IEA
 biological_processGO:0072659 protein localization to plasma membrane IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0030496 midbody IEA
 cellular_componentGO:0055037 recycling endosome IEA
 cellular_componentGO:0055038 recycling endosome membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0003924 GTPase activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding ISO
 molecular_functionGO:0019003 GDP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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