ENSMUSG00000050029


Mus musculus

Features
Gene ID: ENSMUSG00000050029
  
Biological name :Rap2c
  
Synonyms : Q8BU31 / Rap2c / Ras-related protein Rap-2c
  
Possible biological names infered from orthology : Q9Y3L5 / RAP2C, member of RAS oncogene family
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: A5
Gene start: 51003912
Gene end: 51018018
  
Corresponding Affymetrix probe sets: 10604523 (MoGene1.0st)   1428119_a_at (Mouse Genome 430 2.0 Array)   1437016_x_at (Mouse Genome 430 2.0 Array)   1460430_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000058391
NCBI entrez gene - 72065     See in Manteia.
MGI - MGI:1919315
RefSeq - XM_006541546
RefSeq - NM_172413
RefSeq - XM_006541545
RefSeq Peptide - NP_766001
swissprot - Q8BU31
Ensembl - ENSMUSG00000050029
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rap2cENSDARG00000015649Danio rerio
 RAP2CENSG00000123728Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rap2a / Q80ZJ1 / Ras-related protein Rap-2a / P10114* / RAP2A, member of RAS oncogene family*ENSMUSG0000005161591
Rap2b / P61226 / RAP2B, member of RAS oncogene family / P61225*ENSMUSG0000003689486
Rap1a / P62835 / RAS-related protein 1a / P62834* / RAP1A, member of RAS oncogene family*ENSMUSG0000006879862
Rap1b / Q99JI6 / RAS related protein 1b / P61224* / RAP1B, member of RAS oncogene family*ENSMUSG0000005268161
Diras2 / Q5PR73 / GTP-binding protein Di-Ras2 / Q96HU8* / DIRAS family GTPase 2*ENSMUSG0000004784249
Diras1 / Q91Z61 / GTP-binding protein Di-Ras1 / O95057* / DIRAS family GTPase 1*ENSMUSG0000004367046
Gm266ENSMUSG0000001052945
Rit1 / P70426 / GTP-binding protein Rit1 / Q92963* / Ras like without CAAX 1*ENSMUSG0000002805744
Rit2 / P70425 / GTP-binding protein Rit2 / Q99578* / Ras like without CAAX 2*ENSMUSG0000005745543
Rasd1 / O35626 / Dexamethasone-induced Ras-related protein 1 / Q9Y272* / ras related dexamethasone induced 1*ENSMUSG0000004989239
Rasd2 / P63032 / GTP-binding protein Rhes / Q96D21* / RASD family member 2*ENSMUSG0000003447237
Q5SSG5 / Rasl10b / Ras-like protein family member 10B / Q96S79* / RAS like family 10 member B*ENSMUSG0000002068431
Q8K5A4 / Rasl10a / Ras-like protein family member 10A / Q92737* / RAS like family 10 member A*ENSMUSG0000003420930


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR020849  Small GTPase superfamily, Ras-type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0030336 negative regulation of cell migration IDA
 biological_processGO:0031954 positive regulation of protein autophosphorylation IDA
 biological_processGO:0032486 Rap protein signal transduction IDA
 biological_processGO:0061097 regulation of protein tyrosine kinase activity IDA
 biological_processGO:0090557 establishment of endothelial intestinal barrier IEA
 biological_processGO:1903506 regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0044291 cell-cell contact zone IEA
 cellular_componentGO:0055037 recycling endosome IDA
 cellular_componentGO:0055038 recycling endosome membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding ISO
 molecular_functionGO:0019003 GDP binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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