ENSMUSG00000028549


Mus musculus

Features
Gene ID: ENSMUSG00000028549
  
Biological name :Itgb3bp
  
Synonyms : integrin beta 3 binding protein (beta3-endonexin) / Itgb3bp / Q9CQ82
  
Possible biological names infered from orthology : integrin subunit beta 3 binding protein / Q13352
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: C6
Gene start: 99765402
Gene end: 99929813
  
Corresponding Affymetrix probe sets: 10514650 (MoGene1.0st)   1420665_at (Mouse Genome 430 2.0 Array)   1442993_at (Mouse Genome 430 2.0 Array)   1449953_at (Mouse Genome 430 2.0 Array)   1456097_a_at (Mouse Genome 430 2.0 Array)   1459472_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000117153
NCBI entrez gene - 67733     See in Manteia.
MGI - MGI:1914983
RefSeq - NM_026348
RefSeq - XM_011240600
RefSeq Peptide - NP_080624
swissprot - Q9CQ82
Ensembl - ENSMUSG00000028549
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q13352ENSG00000142856Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009601  Centromere protein R


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0034080 CENP-A containing nucleosome assembly IEA
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005694 chromosome IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
NRIF signals cell death from the nucleus
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Deposition of new CENPA-containing nucleosomes at the centromere
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000000120 Ngfr / nerve growth factor receptor / P08138*  / complex
 ENSMUSG00000003458 Ncstn / P57716 / Nicastrin / Q92542*  / reaction
 ENSMUSG00000015750 Aph1a / Q8BVF7 / Gamma-secretase subunit APH-1A / Q96BI3* / aph-1 homolog A, gamma-secretase subunit*  / reaction
 ENSMUSG00000010609 Psen2 / presenilin 2 / P49810*  / reaction
 ENSMUSG00000015837 Q64337 / Sqstm1 / Sequestosome-1 / Q13501*  / complex / reaction
 ENSMUSG00000032375 Aph1b / Q8C7N7 / Gamma-secretase subunit APH-1B / Q8WW43* / aph-1 homolog B, gamma-secretase subunit*  / reaction
 ENSMUSG00000019969 Psen1 / P49769 / presenilin 1 / P49768*  / reaction
 ENSMUSG00000036835 Psenen / Q9CQR7 / Gamma-secretase subunit PEN-2 / Q9NZ42* / AD000671.1* / presenilin enhancer gamma-secretase subunit*  / reaction
 ENSMUSG00000027859 Ngf / P01139 / Beta-nerve growth factor / P01138* / nerve growth factor*  / complex
 ENSMUSG00000053040 Aph1c / Q9DCZ9 / Putative gamma-secretase subunit APH-1C / APH1B* / Q8WW43* / aph-1 homolog B, gamma-secretase subunit*  / reaction
 ENSMUSG00000027164 Traf6 / P70196 / TNF receptor-associated factor 6 / Q9Y4K3*  / reaction / complex






 

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