ENSMUSG00000028651


Mus musculus

Features
Gene ID: ENSMUSG00000028651
  
Biological name :Ppie
  
Synonyms : Peptidyl-prolyl cis-trans isomerase E / Ppie / Q9QZH3
  
Possible biological names infered from orthology : peptidylprolyl isomerase E / Q9UNP9
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: D2.2
Gene start: 123127115
Gene end: 123139951
  
Corresponding Affymetrix probe sets: 10516081 (MoGene1.0st)   1450657_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000030404
NCBI entrez gene - 56031     See in Manteia.
MGI - MGI:1917118
RefSeq - XM_006503250
RefSeq - NM_019489
RefSeq - XM_006503249
RefSeq Peptide - NP_062362
swissprot - Q9QZH3
Ensembl - ENSMUSG00000028651
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppieENSDARG00000103234Danio rerio
 PPIEENSGALG00000013383Gallus gallus
 PPIEENSG00000084072Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9ERU9 / Ranbp2 / E3 SUMO-protein ligase RanBP2 / RGPD3* / RGPD2* / RGPD1* / RGPD8* / RGPD6* / RGPD5* / RGPD4* / A6NKT7* / O14715* / P0DJD0* / P0DJD1* / P49792* / Q7Z3J3* / Q99666* / RAN b...ENSMUSG0000000322643
Ppif / Q99KR7 / Peptidyl-prolyl cis-trans isomerase F, mitochondrial / P30405* / peptidylprolyl isomerase F*ENSMUSG0000002186838
Ppia / P17742 / peptidylprolyl isomerase A / P62937*ENSMUSG0000007186636
Gm5160 / PPIA* / P62937* / peptidylprolyl isomerase A*ENSMUSG0000005579529
Gm12728ENSMUSG0000008378015


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR002130  Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
 IPR016304  Peptidyl-prolyl cis-trans isomerase E
 IPR020892  Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site
 IPR024936  Cyclophilin-type peptidyl-prolyl cis-trans isomerase
 IPR029000  Cyclophilin-like domain superfamily
 IPR034168  Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome IEA
 biological_processGO:0000413 protein peptidyl-prolyl isomerization IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0045070 positive regulation of viral genome replication IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005681 spliceosomal complex IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0071007 U2-type catalytic step 2 spliceosome IEA
 cellular_componentGO:0071013 catalytic step 2 spliceosome IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding IEA
 molecular_functionGO:0003755 peptidyl-prolyl cis-trans isomerase activity IBA
 molecular_functionGO:0008143 poly(A) binding IEA
 molecular_functionGO:0016853 isomerase activity IEA


Pathways (from Reactome)
Pathway description
Formation of TC-NER Pre-Incision Complex
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Neutrophil degranulation
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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