ENSMUSG00000031373


Mus musculus

Features
Gene ID: ENSMUSG00000031373
  
Biological name :Car5b
  
Synonyms : Car5b / Carbonic anhydrase 5B, mitochondrial / Q9QZA0
  
Possible biological names infered from orthology : CA5B / carbonic anhydrase 5B / Q9Y2D0
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: F5
Gene start: 163976822
Gene end: 164027997
  
Corresponding Affymetrix probe sets: 10607738 (MoGene1.0st)   1419705_at (Mouse Genome 430 2.0 Array)   1447928_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000033739
NCBI entrez gene - 56078     See in Manteia.
MGI - MGI:1926249
RefSeq - NM_181315
RefSeq Peptide - NP_851832
swissprot - Q9QZA0
Ensembl - ENSMUSG00000031373
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ca5aENSDARG00000101778Danio rerio
 ENSGALG00000005855Gallus gallus
 CA5BENSG00000169239Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Car5a / P23589 / Carbonic anhydrase 5A, mitochondrial / CA5A* / P35218* / carbonic anhydrase 5A*ENSMUSG0000002531754
Car7 / Q9ERQ8 / Carbonic anhydrase 7 / CA7* / P43166*ENSMUSG0000003188344
Car13 / Q9D6N1 / Carbonic anhydrase 13 / CA13* / Q8N1Q1*ENSMUSG0000002755544
Car2 / P00920 / Mus musculus carbonic anhydrase 2 (Car2), transcript variant 2, mRNA. / CA2* / P00918* / carbonic anhydrase 2*ENSMUSG0000002756243
Car1 / P13634 / Carbonic anhydrase 1 / CA1* / P00915*ENSMUSG0000002755641
Car3 / P16015 / Carbonic anhydrase 3 / CA3* / P07451*ENSMUSG0000002755939
Car8 / P28651 / Carbonic anhydrase-related protein / CA8* / P35219* / carbonic anhydrase 8*ENSMUSG0000004126131
Car15 / Q99N23 / Carbonic anhydrase 15 ENSMUSG0000009023628
Car12 / carbonic anhydrase 12 / CA12* / O43570*ENSMUSG0000003237327
Car14 / Q9WVT6 / Mus musculus carbonic anhydrase 14 (Car14), transcript variant 2, mRNA. / CA14* / Q9ULX7* / carbonic anhydrase 14*ENSMUSG0000003852626
Car9 / Q8VHB5 / Carbonic anhydrase 9 / CA9* / Q16790*ENSMUSG0000002846326
Car4 / Q64444 / Carbonic anhydrase 4 / CA4* / P22748*ENSMUSG0000000080525
Car6 / P18761 / Carbonic anhydrase 6 / CA6* / P23280*ENSMUSG0000002897223


Protein motifs (from Interpro)
Interpro ID Name
 IPR001148  Alpha carbonic anhydrase domain
 IPR018338  Carbonic anhydrase, alpha-class, conserved site
 IPR018437  Carbonic anhydrase VB, mitochondria
 IPR023561  Carbonic anhydrase, alpha-class
 IPR036398  Alpha carbonic anhydrase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006730 one-carbon metabolic process IEA
 cellular_componentGO:0005739 mitochondrion ISO
 molecular_functionGO:0004089 carbonate dehydratase activity IDA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Reversible hydration of carbon dioxide


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Car5atm1Sly/Car5atm1Sly,Car5btm1Sly/Car5btm1Sly
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Car5atm1Sly/Car5atm1Sly,Car5btm1Sly/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Car5atm1Sly/Car5atm1Sly,Car5btm1Sly/Car5btm1Sly
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Car5atm1Sly/Car5atm1Sly,Car5btm1Sly/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0003674 oxidative stress "condition characterized by an accumulation of free radical groups in the body, which creates a potentially unstable and damaging cellular environment linked to tissue damage, accelerated aging, and degenerative disease; can result from many factors, including exposure to alcohol, medications, poor nutrition, trauma, cold or toxins; may be indicated by low antioxidant levels measured in blood plasma" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Car5atm1Sly/Car5atm1Sly,Car5btm1Sly/Car5btm1Sly
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Car5atm1Sly/Car5atm1Sly,Car5btm1Sly/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0005309 increased circulating ammonia level "significantly elevated levels of ammonia or its compounds in blood; often associated with liver failure and hepatic encephalopathy " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83263]
Show

Allelic Composition: Car5atm1Sly/Car5atm1Sly,Car5btm1Sly/Car5btm1Sly
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Car5atm1Sly/Car5atm1Sly,Car5btm1Sly/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Car5atm1Sly/Car5atm1Sly,Car5btm1Sly/Car5btm1Sly
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Car5atm1Sly/Car5atm1Sly,Car5btm1Sly/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Car5atm1Sly/Car5atm1Sly,Car5btm1Sly/Car5btm1Sly
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Car5atm1Sly/Car5atm1Sly,Car5btm1Sly/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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