ENSMUSG00000032373


Mus musculus

Features
Gene ID: ENSMUSG00000032373
  
Biological name :Car12
  
Synonyms : Car12 / carbonic anhydrase 12
  
Possible biological names infered from orthology : CA12 / O43570
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: C
Gene start: 66713686
Gene end: 66766845
  
Corresponding Affymetrix probe sets: 10586591 (MoGene1.0st)   1428485_at (Mouse Genome 430 2.0 Array)   1447762_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000118030
Ensembl peptide - ENSMUSP00000071786
Ensembl peptide - ENSMUSP00000082541
NCBI entrez gene - 76459     See in Manteia.
MGI - MGI:1923709
RefSeq - NM_178396
RefSeq - XM_006511548
RefSeq - NM_001306148
RefSeq Peptide - NP_001293077
RefSeq Peptide - NP_848483
swissprot - A0A0R4J0W4
swissprot - Q8K2J1
swissprot - F6W0I8
Ensembl - ENSMUSG00000032373
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ca12ENSDARG00000045644Danio rerio
 CA12ENSGALG00000003456Gallus gallus
 CA12ENSG00000074410Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Car14 / Q9WVT6 / Mus musculus carbonic anhydrase 14 (Car14), transcript variant 2, mRNA. / CA14* / Q9ULX7* / carbonic anhydrase 14*ENSMUSG0000003852636
Car9 / Q8VHB5 / Carbonic anhydrase 9 / CA9* / Q16790*ENSMUSG0000002846333
Car7 / Q9ERQ8 / Carbonic anhydrase 7 / CA7* / P43166*ENSMUSG0000003188330
Car13 / Q9D6N1 / Carbonic anhydrase 13 / CA13* / Q8N1Q1*ENSMUSG0000002755529
Car15 / Q99N23 / Carbonic anhydrase 15 ENSMUSG0000009023629
Car1 / P13634 / Carbonic anhydrase 1 / CA1* / P00915*ENSMUSG0000002755629
Car6 / P18761 / Carbonic anhydrase 6 / CA6* / P23280*ENSMUSG0000002897228
Car4 / Q64444 / Carbonic anhydrase 4 / CA4* / P22748*ENSMUSG0000000080526
Car2 / P00920 / Mus musculus carbonic anhydrase 2 (Car2), transcript variant 2, mRNA. / CA2* / P00918* / carbonic anhydrase 2*ENSMUSG0000002756226
Car5b / Q9QZA0 / Carbonic anhydrase 5B, mitochondrial / CA5B* / Q9Y2D0* / carbonic anhydrase 5B*ENSMUSG0000003137325
Car5a / P23589 / Carbonic anhydrase 5A, mitochondrial / CA5A* / P35218* / carbonic anhydrase 5A*ENSMUSG0000002531725
Car3 / P16015 / Carbonic anhydrase 3 / CA3* / P07451*ENSMUSG0000002755925
Car8 / P28651 / Carbonic anhydrase-related protein / CA8* / P35219* / carbonic anhydrase 8*ENSMUSG0000004126125


Protein motifs (from Interpro)
Interpro ID Name
 IPR001148  Alpha carbonic anhydrase domain
 IPR018338  Carbonic anhydrase, alpha-class, conserved site
 IPR018430  Carbonic anhydrase, CA-XII
 IPR023561  Carbonic anhydrase, alpha-class
 IPR036398  Alpha carbonic anhydrase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006730 one-carbon metabolic process IEA
 biological_processGO:0055064 chloride ion homeostasis IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004089 carbonate dehydratase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Reversible hydration of carbon dioxide


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cdh23ahl/Cdh23ahl,Adgrv1frings/Adgrv1frings
Genetic Background: involves: BUB/BnJ * RB/1

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000032373 Car12 / carbonic anhydrase 12 / CA12* / O43570*  / complex






 

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