ENSMUSG00000031883


Mus musculus

Features
Gene ID: ENSMUSG00000031883
  
Biological name :Car7
  
Synonyms : Car7 / Carbonic anhydrase 7 / Q9ERQ8
  
Possible biological names infered from orthology : CA7 / P43166
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: D3
Gene start: 104534689
Gene end: 104550343
  
Corresponding Affymetrix probe sets: 10574480 (MoGene1.0st)   1434973_at (Mouse Genome 430 2.0 Array)   1443824_s_at (Mouse Genome 430 2.0 Array)   1452484_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000052136
Ensembl peptide - ENSMUSP00000125112
Ensembl peptide - ENSMUSP00000125404
NCBI entrez gene - 12354     See in Manteia.
MGI - MGI:103100
RefSeq - XM_017312542
RefSeq - NM_001301164
RefSeq - NM_001301165
RefSeq - NM_053070
RefSeq - XM_006530617
RefSeq - XM_006530618
RefSeq Peptide - NP_444300
RefSeq Peptide - NP_001288093
RefSeq Peptide - NP_001288094
swissprot - Q9ERQ8
swissprot - G3XA26
Ensembl - ENSMUSG00000031883
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ca7ENSDARG00000045139Danio rerio
 CA7ENSGALG00000033720Gallus gallus
 CA7ENSG00000168748Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Car2 / P00920 / Mus musculus carbonic anhydrase 2 (Car2), transcript variant 2, mRNA. / CA2* / P00918* / carbonic anhydrase 2*ENSMUSG0000002756254
Car13 / Q9D6N1 / Carbonic anhydrase 13 / CA13* / Q8N1Q1*ENSMUSG0000002755553
Car5b / Q9QZA0 / Carbonic anhydrase 5B, mitochondrial / CA5B* / Q9Y2D0* / carbonic anhydrase 5B*ENSMUSG0000003137353
Car3 / P16015 / Carbonic anhydrase 3 / CA3* / P07451*ENSMUSG0000002755951
Car1 / P13634 / Carbonic anhydrase 1 / CA1* / P00915*ENSMUSG0000002755650
Car5a / P23589 / Carbonic anhydrase 5A, mitochondrial / CA5A* / P35218* / carbonic anhydrase 5A*ENSMUSG0000002531748
Car8 / P28651 / Carbonic anhydrase-related protein / CA8* / P35219* / carbonic anhydrase 8*ENSMUSG0000004126142
Car12 / carbonic anhydrase 12 / CA12* / O43570*ENSMUSG0000003237340
Car9 / Q8VHB5 / Carbonic anhydrase 9 / CA9* / Q16790*ENSMUSG0000002846337
Car14 / Q9WVT6 / Mus musculus carbonic anhydrase 14 (Car14), transcript variant 2, mRNA. / CA14* / Q9ULX7* / carbonic anhydrase 14*ENSMUSG0000003852637
Car15 / Q99N23 / Carbonic anhydrase 15 ENSMUSG0000009023634
Car6 / P18761 / Carbonic anhydrase 6 / CA6* / P23280*ENSMUSG0000002897234
Car4 / Q64444 / Carbonic anhydrase 4 / CA4* / P22748*ENSMUSG0000000080532


Protein motifs (from Interpro)
Interpro ID Name
 IPR001148  Alpha carbonic anhydrase domain
 IPR018338  Carbonic anhydrase, alpha-class, conserved site
 IPR023561  Carbonic anhydrase, alpha-class
 IPR036398  Alpha carbonic anhydrase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006730 one-carbon metabolic process IEA
 biological_processGO:0032230 positive regulation of synaptic transmission, GABAergic IGI
 biological_processGO:0032849 positive regulation of cellular pH reduction IMP
 biological_processGO:2001225 regulation of chloride transport IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0004089 carbonate dehydratase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Reversible hydration of carbon dioxide


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000062 increased bone density "increased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61295]
Show

Allelic Composition: Cacna1stm1.1(KOMP)Vlcg/Cacna1stm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cacna1stm1.1(KOMP)Vlcg/J

 MP:0001257 increased body length "increased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
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Allelic Composition: Cacna1stm1.1(KOMP)Vlcg/Cacna1stm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cacna1stm1.1(KOMP)Vlcg/J

 MP:0001417 decreased exploration in new environment "less amount of time spent investigating a new location" [J:79870]
Show

Allelic Composition: Cacna1stm1.1(KOMP)Vlcg/Cacna1stm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cacna1stm1.1(KOMP)Vlcg/J

 MP:0001554 increased circulating free fatty acid level "higher than normal levels of unesterified fatty acids in the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:65146]
Show

Allelic Composition: Cacna1stm1.1(KOMP)Vlcg/Cacna1stm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cacna1stm1.1(KOMP)Vlcg/J

 MP:0003960 increased lean body mass "more than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
Show

Allelic Composition: Cacna1stm1.1(KOMP)Vlcg/Cacna1stm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cacna1stm1.1(KOMP)Vlcg/J

 MP:0004008 abnormal GABA receptor currents "change in the measured amplitude or duration of response to stimulation of GABA receptors" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Nmnat2Gt(EUCE0262a08)1.1Hmgu/Nmnat2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL

Allelic Composition: Car2n/Car2n,Car7tm1.1Kkai/Car7tm1.1Kkai
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2J

 MP:0005565 increased blood urea nitrogen level "high circulating concentration of nitrogen, in the form of urea; commonly used to measure renal function" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Cacna1stm1.1(KOMP)Vlcg/Cacna1stm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cacna1stm1.1(KOMP)Vlcg/J

 MP:0009358 environmentally induced seizures "relatively mild but sudden stimulation due to changes in ambient habitat including lighting, sounds, touching, and/ or moving cage" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Nmnat2Gt(EUCE0262a08)1.1Hmgu/Nmnat2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL

 MP:0010024 increased total body fat amount "greater than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cacna1stm1.1(KOMP)Vlcg/Cacna1stm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cacna1stm1.1(KOMP)Vlcg/J

 MP:0010123 increased bone mineral content "elevation in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cacna1stm1.1(KOMP)Vlcg/Cacna1stm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cacna1stm1.1(KOMP)Vlcg/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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