ENSMUSG00000032349


Mus musculus

Features
Gene ID: ENSMUSG00000032349
  
Biological name :Elovl5
  
Synonyms : Elongation of very long chain fatty acids protein 5 / Elovl5 / Q8BHI7
  
Possible biological names infered from orthology : ELOVL fatty acid elongase 5 / Q9NYP7
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: E1
Gene start: 77917364
Gene end: 77984519
  
Corresponding Affymetrix probe sets: 10587284 (MoGene1.0st)   1415840_at (Mouse Genome 430 2.0 Array)   1437211_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000120171
Ensembl peptide - ENSMUSP00000123121
Ensembl peptide - ENSMUSP00000034904
NCBI entrez gene - 68801     See in Manteia.
MGI - MGI:1916051
RefSeq - XM_006511400
RefSeq - XM_011242807
RefSeq - NM_134255
RefSeq Peptide - NP_599016
swissprot - Q8BHI7
swissprot - D3Z136
swissprot - D3Z0Z6
Ensembl - ENSMUSG00000032349
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 elovl5ENSDARG00000004979Danio rerio
 ELOVL5ENSGALG00000016314Gallus gallus
 ELOVL5ENSG00000012660Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Elovl2 / Q9JLJ4 / Elongation of very long chain fatty acids protein 2 / Q9NXB9* / ELOVL fatty acid elongase 2*ENSMUSG0000002136457
Elovl4 / Q9EQC4 / Elongation of very long chain fatty acids protein 4 / Q9GZR5* / ELOVL fatty acid elongase 4*ENSMUSG0000003226242
Elovl7 / Q9D2Y9 / Elongation of very long chain fatty acids protein 7 / A1L3X0* / ELOVL fatty acid elongase 7*ENSMUSG0000002169634
Elovl1 / Q9JLJ5 / Elongation of very long chain fatty acids protein 1 / Q9BW60* / ELOVL fatty acid elongase 1*ENSMUSG0000000639033
Elovl6 / Q920L5 / Elongation of very long chain fatty acids protein 6 / Q9H5J4* / ELOVL fatty acid elongase 6*ENSMUSG0000004122021
Elovl3 / O35949 / Elongation of very long chain fatty acids protein 3 / Q9HB03* / ELOVL fatty acid elongase 3*ENSMUSG0000003875420


Protein motifs (from Interpro)
Interpro ID Name
 IPR002076  ELO family
 IPR033677  Elongation of very long chain fatty acids protein 5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006633 fatty acid biosynthetic process IEA
 biological_processGO:0006636 unsaturated fatty acid biosynthetic process IEA
 biological_processGO:0019367 fatty acid elongation, saturated fatty acid IEA
 biological_processGO:0030148 sphingolipid biosynthetic process IBA
 biological_processGO:0034625 fatty acid elongation, monounsaturated fatty acid IEA
 biological_processGO:0034626 fatty acid elongation, polyunsaturated fatty acid IEA
 biological_processGO:0042761 very long-chain fatty acid biosynthetic process IEA
 biological_processGO:0045723 positive regulation of fatty acid biosynthetic process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IBA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0097447 dendritic tree IEA
 molecular_functionGO:0009922 fatty acid elongase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0102336 3-oxo-arachidoyl-CoA synthase activity IEA
 molecular_functionGO:0102337 3-oxo-cerotoyl-CoA synthase activity IEA
 molecular_functionGO:0102338 3-oxo-lignoceronyl-CoA synthase activity IEA
 molecular_functionGO:0102756 very-long-chain 3-ketoacyl-CoA synthase activity IEA


Pathways (from Reactome)
Pathway description
Linoleic acid (LA) metabolism
alpha-linolenic acid (ALA) metabolism
Synthesis of very long-chain fatty acyl-CoAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000609 abnormal liver physiology "aberrant function of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Ldlrtm1Her/Ldlrtm1Her,Nr0b2tm1.1Mjev/Nr0b2tm1.1Mjev
Genetic Background: involves: 129S/SvEvBrd * 129S4/SvJae * 129S7/SvEvBrd * C57BL/6

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: Ldlrtm1Her/Ldlrtm1Her,Nr0b2tm1.1Mjev/Nr0b2tm1.1Mjev
Genetic Background: involves: 129S/SvEvBrd * 129S4/SvJae * 129S7/SvEvBrd * C57BL/6

 MP:0002628 fatty liver "an accumulation of fat deposits in the liver " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ldlrtm1Her/Ldlrtm1Her,Nr0b2tm1.1Mjev/Nr0b2tm1.1Mjev
Genetic Background: involves: 129S/SvEvBrd * 129S4/SvJae * 129S7/SvEvBrd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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