ENSMUSG00000032998


Mus musculus

Features
Gene ID: ENSMUSG00000032998
  
Biological name :Foxj3
  
Synonyms : Forkhead box protein J3 / Foxj3 / Q8BUR3
  
Possible biological names infered from orthology : forkhead box J3 / Q9UPW0
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: D2.1
Gene start: 119537004
Gene end: 119629119
  
Corresponding Affymetrix probe sets: 10507657 (MoGene1.0st)   1435362_at (Mouse Genome 430 2.0 Array)   1438220_at (Mouse Genome 430 2.0 Array)   1459055_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000123923
Ensembl peptide - ENSMUSP00000124806
Ensembl peptide - ENSMUSP00000135430
Ensembl peptide - ENSMUSP00000035746
Ensembl peptide - ENSMUSP00000101917
Ensembl peptide - ENSMUSP00000123815
Ensembl peptide - ENSMUSP00000123826
NCBI entrez gene - 230700     See in Manteia.
MGI - MGI:2443432
RefSeq - XM_017320150
RefSeq - XM_006503017
RefSeq - XM_011240497
RefSeq - NM_001290696
RefSeq - NM_172699
RefSeq Peptide - NP_001344106
RefSeq Peptide - NP_001277625
RefSeq Peptide - NP_766287
swissprot - Q3TAY5
swissprot - Q8BUR3
swissprot - E0CYX1
swissprot - E0CYS8
swissprot - H3BKK7
Ensembl - ENSMUSG00000032998
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 foxj3ENSDARG00000075774Danio rerio
 FOXJ3ENSG00000198815Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Foxj2 / Q9ES18 / Forkhead box protein J2 / Q9P0K8* / forkhead box J2*ENSMUSG0000000315438
Foxn1 / Q61575 / Forkhead box protein N1 / O15353* / forkhead box N1*ENSMUSG0000000205716
Foxk2 / Q3UCQ1 / Forkhead box protein K2 / Q01167* / forkhead box K2*ENSMUSG0000003927516
Foxj1 / Q61660 / Forkhead box protein J1 / Q92949* / forkhead box J1*ENSMUSG0000003422715
Foxk1 / P42128 / Forkhead box protein K1 / P85037* / forkhead box K1*ENSMUSG0000005649315
Foxn2 / Mus musculus forkhead box N2 (Foxn2), transcript variant 3, mRNA. / P32314* / forkhead box N2*ENSMUSG0000003499815
Foxn3 / Q499D0 / Forkhead box protein N3 / O00409* / forkhead box N3*ENSMUSG0000003371314
Foxn4 / Q8K3Q3 / Forkhead box protein N4 / Q96NZ1* / forkhead box N4*ENSMUSG0000004200214


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR018122  Fork head domain conserved site1
 IPR030456  Fork head domain conserved site 2
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000367 abnormal coat/ hair morphology "anomalous color, structure, growth, or texture of the hair" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Fgf9tm1b(KOMP)Wtsi/Fgf9tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Fgf9tm1b(KOMP)Wtsi/H

 MP:0001415 increased exploration in new environment "greater amount of time spent investigating new location" [J:28825]
Show

Allelic Composition: Fgf9tm1b(KOMP)Wtsi/Fgf9tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Fgf9tm1b(KOMP)Wtsi/H

 MP:0002092 abnormal eye morphology "abnormal development of the eye tissues resulting in morphological abnormality or abnormal structure of the visual system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Fgf9tm1b(KOMP)Wtsi/Fgf9tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Fgf9tm1b(KOMP)Wtsi/H

 MP:0002106 abnormal muscle physiology "anomolous function of the muscle, not due to an anatomical defect" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Terf1tm2.1Tdl/Terf1tm2.1Tdl
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002841 impaired skeletal muscle contractility "inability or reduced ability of the skeletal muscle to shorten or to develop increased tension" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Terf1tm2.1Tdl/Terf1tm2.1Tdl
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0003081 abnormal soleus morphology "anomaly in the the superficial flat broad muscle of the calf that is responsible for plantar flexion of the foot" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, smb:Susan M. Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Terf1tm2.1Tdl/Terf1tm2.1Tdl
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0003795 abnormal bone structure 
Show

Allelic Composition: Fgf9tm1b(KOMP)Wtsi/Fgf9tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Fgf9tm1b(KOMP)Wtsi/H

 MP:0003852 skeletal muscle necrosis "pathological cell death in the skeletal muscle, usually due to irreversible damage" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Terf1tm2.1Tdl/Terf1tm2.1Tdl
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0004246 abnormal extensor digitorum longus morphology "any structural anomaly of penniform muscle of the lateral front part of the leg responsible for extension of the toes and dorsiflexion of the ankle" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Terf1tm2.1Tdl/Terf1tm2.1Tdl
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0009409 abnormal skeletal muscle fiber type ratio "deviation from the standard ratios of fiber types in a given skeletal muscle compared to control samples" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Terf1tm2.1Tdl/Terf1tm2.1Tdl
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0009410 abnormal skeletal muscle satellite cell proliferation "anomaly in the ability of unfused cells in skeltal muscle to undergo expansion by cell division, usually triggered by injury or disease" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Terf1tm2.1Tdl/Terf1tm2.1Tdl
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0010025 decreased total body fat amount "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fgf9tm1b(KOMP)Wtsi/Fgf9tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Fgf9tm1b(KOMP)Wtsi/H

 MP:0010123 increased bone mineral content "elevation in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fgf9tm1b(KOMP)Wtsi/Fgf9tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Fgf9tm1b(KOMP)Wtsi/H

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Fgf9tm1b(KOMP)Wtsi/Fgf9tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Fgf9tm1b(KOMP)Wtsi/H

 MP:0011239 abnormal skin coloration "a variation in an expected skin color or complexion that may be due to inflammation, pigment defects or other causes" [MGI:llw2]
Show

Allelic Composition: Fgf9tm1b(KOMP)Wtsi/Fgf9tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Fgf9tm1b(KOMP)Wtsi/H

 MP:0013239 impaired skeletal muscle regeneration "reduced ability to repair skeletal muscle after injury or disease" [MGI:csmith]
Show

Allelic Composition: Terf1tm2.1Tdl/Terf1tm2.1Tdl
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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