ENSMUSG00000039275


Mus musculus

Features
Gene ID: ENSMUSG00000039275
  
Biological name :Foxk2
  
Synonyms : Forkhead box protein K2 / Foxk2 / Q3UCQ1
  
Possible biological names infered from orthology : forkhead box K2 / Q01167
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: E2
Gene start: 121259990
Gene end: 121309896
  
Corresponding Affymetrix probe sets: 10383545 (MoGene1.0st)   1428353_at (Mouse Genome 430 2.0 Array)   1428354_at (Mouse Genome 430 2.0 Array)   1440689_at (Mouse Genome 430 2.0 Array)   1442933_at (Mouse Genome 430 2.0 Array)   1452753_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000101719
NCBI entrez gene - 68837     See in Manteia.
MGI - MGI:1916087
RefSeq - XM_011249221
RefSeq - NM_001080932
RefSeq - XM_011249219
RefSeq - XM_011249220
RefSeq - XM_006534082
RefSeq - XM_011249218
RefSeq Peptide - NP_001074401
swissprot - Q3UCQ1
Ensembl - ENSMUSG00000039275
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 foxk2ENSDARG00000030583Danio rerio
 si:ch211-262e15.1ENSDARG00000011609Danio rerio
 FOXK2ENSGALG00000001577Gallus gallus
 FOXK2ENSG00000141568Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Foxk1 / P42128 / Forkhead box protein K1 / P85037* / forkhead box K1*ENSMUSG0000005649355
Foxj3 / Q8BUR3 / Forkhead box protein J3 / Q9UPW0* / forkhead box J3*ENSMUSG0000003299816
Foxn3 / Q499D0 / Forkhead box protein N3 / O00409* / forkhead box N3*ENSMUSG0000003371315
Foxj2 / Q9ES18 / Forkhead box protein J2 / Q9P0K8* / forkhead box J2*ENSMUSG0000000315415
Foxn2 / Mus musculus forkhead box N2 (Foxn2), transcript variant 3, mRNA. / P32314* / forkhead box N2*ENSMUSG0000003499815
Foxj1 / Q61660 / Forkhead box protein J1 / Q92949* / forkhead box J1*ENSMUSG0000003422715
Foxn4 / Q8K3Q3 / Forkhead box protein N4 / Q96NZ1* / forkhead box N4*ENSMUSG0000004200214
Foxn1 / Q61575 / Forkhead box protein N1 / O15353* / forkhead box N1*ENSMUSG0000000205713


Protein motifs (from Interpro)
Interpro ID Name
 IPR000253  Forkhead-associated (FHA) domain
 IPR001766  Fork head domain
 IPR008984  SMAD/FHA domain superfamily
 IPR018122  Fork head domain conserved site1
 IPR030456  Fork head domain conserved site 2
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding ISS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
UCH proteinases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000021901 Bap1 / Q99PU7 / Ubiquitin carboxyl-terminal hydrolase BAP1 / Q92560* / BRCA1 associated protein 1*  / reaction / complex
 ENSMUSG00000031386 Hcfc1 / Q61191 / Host cell factor 1 HCF N-terminal chain 1 HCF N-terminal chain 2 HCF N-terminal chain 3 HCF N-terminal chain 4 HCF N-terminal chain 5 HCF N-terminal chain 6 HCF C-terminal c...  / complex
 ENSMUSG00000034160 Ogt / Q8CGY8 / UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit / O15294* / O-linked N-acetylglucosamine (GlcNAc) transferase*  / complex
 ENSMUSG00000021264 Yy1 / Q00899 / YY1 transcription factor / P25490*  / complex
 ENSMUSG00000042548 Asxl1 / P59598 / Putative Polycomb group protein ASXL1 / Q8IXJ9* / additional sex combs like 1, transcriptional regulator*  / complex






 

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