ENSMUSG00000033214


Mus musculus

Features
Gene ID: ENSMUSG00000033214
  
Biological name :Slitrk5
  
Synonyms : Q810B7 / SLIT and NTRK-like protein 5 / Slitrk5
  
Possible biological names infered from orthology : O94991 / SLIT and NTRK like family member 5
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: E4
Gene start: 111675097
Gene end: 111683141
  
Corresponding Affymetrix probe sets: 10416931 (MoGene1.0st)   1429718_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000041499
Ensembl peptide - ENSMUSP00000154387
NCBI entrez gene - 75409     See in Manteia.
MGI - MGI:2679448
RefSeq - XM_006519643
RefSeq - NM_198865
RefSeq - XM_006519641
RefSeq - XM_006519642
RefSeq Peptide - NP_942565
swissprot - Q810B7
Ensembl - ENSMUSG00000033214
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slitrk5aENSDARG00000103359Danio rerio
 slitrk5bENSDARG00000074153Danio rerio
 SLITRK5ENSGALG00000026361Gallus gallus
 O94991ENSG00000165300Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q810C0 / Slitrk2 / SLIT and NTRK-like family, member 2 / O96002* / Q9H156*ENSMUSG0000003679045
Q810B9 / Slitrk3 / Mus musculus SLIT and NTRK-like family, member 3 (Slitrk3), transcript variant 2, mRNA. / O94933* / SLIT and NTRK like family member 3*ENSMUSG0000004830441
Q810B8 / Slitrk4 / SLIT and NTRK-like family, member 4 / Q8IW52*ENSMUSG0000004669939
Q8C110 / Slitrk6 / SLIT and NTRK-like family, member 6 / Q9H5Y7*ENSMUSG0000004587137
Q810C1 / Slitrk1 / SLIT and NTRK-like family, member 1 / Q96PX8*ENSMUSG0000007547830
Elfn2 / Q68FM6 / Mus musculus leucine rich repeat and fibronectin type III, extracellular 2 (Elfn2), transcript variant 1, mRNA. / Q5R3F8* / extracellular leucine rich repeat and fibronecti...ENSMUSG0000004346013
Elfn1 / Q8C8T7 / Protein ELFN1 / P0C7U0* / extracellular leucine rich repeat and fibronectin type III domain containing 1*ENSMUSG0000004898813
Lrrc19 / Q8BZT5 / Leucine-rich repeat-containing protein 19 / Q9H756* / leucine rich repeat containing 19*ENSMUSG000000497998


Protein motifs (from Interpro)
Interpro ID Name
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007268 chemical synaptic transmission IMP
 biological_processGO:0007409 axonogenesis IDA
 biological_processGO:0007625 grooming behavior IMP
 biological_processGO:0009410 response to xenobiotic stimulus IMP
 biological_processGO:0021756 striatum development IMP
 biological_processGO:0030534 adult behavior IMP
 biological_processGO:0043588 skin development IMP
 biological_processGO:0048813 dendrite morphogenesis IMP
 biological_processGO:0051965 positive regulation of synapse assembly IDA
 biological_processGO:0072358 cardiovascular system development IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISS
 cellular_componentGO:0043235 receptor complex IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Receptor-type tyrosine-protein phosphatases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000414 alopecia "absence of hair or loss of hair; not usually in reference to primary genetic hairlessness but may be due to dietary, stress, secondary to immune condition" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:30772, J:33796]
Show

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

 MP:0001212 skin lesions "focal patches of inflammation on the skin" [J:30162]
Show

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

Allelic Composition: Slitrk5tm2Vlcg/Slitrk5+
Genetic Background: involves: 129S/Sv * C57BL/6

 MP:0001363 increased anxiety-related response "when compared to controls, subjects exhibit more responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:49752, J:53060]
Show

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

 MP:0001441 increased grooming behavior "increased amount of time spent cleaning and/or keeping outward appearance tidy (self, mate or offspring)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

Allelic Composition: Slitrk5tm2Vlcg/Slitrk5+
Genetic Background: involves: 129S/Sv * C57BL/6

 MP:0001914 hemorrhage "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

 MP:0003635 abnormal synaptic transmission "defect in the communication from a neuron to a target across a synapse " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

 MP:0004077 abnormal striatum morphology "malformation of a large cluster of dopaminergic nerve cells, consisting of the caudate nucleus and the putamen, that controls movement, balance, and walking" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

 MP:0008462 abnormal medium spiny neuron morphology "any structural anomaly of the inhibitory projection neurons located in the striatum that integrate glutamatergic signals arising from the cerebral cortex and thalamus" [PMID:15504319]
Show

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

 MP:0009746 enhanced behavioral response to xenobiotic "increased sensitivity to a foreign compound capable of inducing the appearance of behavioral response, such as consumption preference, induced hyperactivity or stereotypic behavior, or reduced dosage threshold for the appearance of the behavioral response" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr