ENSMUSG00000048304


Mus musculus

Features
Gene ID: ENSMUSG00000048304
  
Biological name :Slitrk3
  
Synonyms : Mus musculus SLIT and NTRK-like family, member 3 (Slitrk3), transcript variant 2, mRNA. / Q810B9 / Slitrk3
  
Possible biological names infered from orthology : O94933 / SLIT and NTRK like family member 3
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: E3
Gene start: 73047265
Gene end: 73057803
  
Corresponding Affymetrix probe sets: 10498707 (MoGene1.0st)   1439250_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000088561
Ensembl peptide - ENSMUSP00000141236
NCBI entrez gene - 386750     See in Manteia.
MGI - MGI:2679447
RefSeq - XM_006501642
RefSeq - NM_001357851
RefSeq - NM_198864
RefSeq - XM_006501639
RefSeq - XM_006501640
RefSeq - XM_006501641
RefSeq - XM_006501638
RefSeq Peptide - NP_942564
RefSeq Peptide - NP_001344780
swissprot - Q810B9
Ensembl - ENSMUSG00000048304
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slitrk3aENSDARG00000078123Danio rerio
 slitrk3bENSDARG00000074739Danio rerio
 SLITRK3ENSGALG00000042159Gallus gallus
 O94933ENSG00000121871Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q810B7 / Slitrk5 / SLIT and NTRK-like protein 5 / O94991* / SLIT and NTRK like family member 5*ENSMUSG0000003321440
Q810C0 / Slitrk2 / SLIT and NTRK-like family, member 2 / O96002* / Q9H156*ENSMUSG0000003679037
Q810B8 / Slitrk4 / SLIT and NTRK-like family, member 4 / Q8IW52*ENSMUSG0000004669935
Q8C110 / Slitrk6 / SLIT and NTRK-like family, member 6 / Q9H5Y7*ENSMUSG0000004587133
Q810C1 / Slitrk1 / SLIT and NTRK-like family, member 1 / Q96PX8*ENSMUSG0000007547828
Elfn2 / Q68FM6 / Mus musculus leucine rich repeat and fibronectin type III, extracellular 2 (Elfn2), transcript variant 1, mRNA. / Q5R3F8* / extracellular leucine rich repeat and fibronecti...ENSMUSG0000004346012
Elfn1 / Q8C8T7 / Protein ELFN1 / P0C7U0* / extracellular leucine rich repeat and fibronectin type III domain containing 1*ENSMUSG0000004898812
Lrrc19 / Q8BZT5 / Leucine-rich repeat-containing protein 19 / Q9H756* / leucine rich repeat containing 19*ENSMUSG000000497998


Protein motifs (from Interpro)
Interpro ID Name
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007409 axonogenesis IDA
 biological_processGO:0051965 positive regulation of synapse assembly IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISS
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Receptor-type tyrosine-protein phosphatases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002064 seizures "sudden and often acute manifestation of epileptic attack, sometimes convulsive" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ptch1tm1Yy/Ptch1+,Trp53tm1Brd/Trp53+,Tg(BGLAP-cre)1Clem/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/NJ

 MP:0002906 susceptibility to pharmacologically induced seizures "inability to withstand doses of pharmacological drugs that induce seizure activity in normal animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:69504]
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Allelic Composition: Ptch1tm1Yy/Ptch1+,Trp53tm1Brd/Trp53+,Tg(BGLAP-cre)1Clem/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/NJ

 MP:0009435 abnormal miniature inhibitory postsynaptic currents "defect in the size or duration of spontaneous currents detected in postsynaptic cells that occur in the absence of an inhibitory impulse" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ptch1tm1Yy/Ptch1+,Trp53tm1Brd/Trp53+,Tg(BGLAP-cre)1Clem/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/NJ

 MP:0009538 abnormal synapse morphology "any strucutral anomaly of the membrane junction site of a nerve cell to a target cell, such as another nerve cell, an effector cell, or a sensory receptor cell; transmission of nerve impulses may be mediated by chemical or by electrical means" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MESH:A08.850]
Show

Allelic Composition: Ptch1tm1Yy/Ptch1+,Trp53tm1Brd/Trp53+,Tg(BGLAP-cre)1Clem/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/NJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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