ENSMUSG00000046699


Mus musculus

Features
Gene ID: ENSMUSG00000046699
  
Biological name :Slitrk4
  
Synonyms : Q810B8 / SLIT and NTRK-like family, member 4 / Slitrk4
  
Possible biological names infered from orthology : Q8IW52
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: A7.1
Gene start: 64264885
Gene end: 64276996
  
Corresponding Affymetrix probe sets: 10604853 (MoGene1.0st)   1437744_at (Mouse Genome 430 2.0 Array)   1440516_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000064443
Ensembl peptide - ENSMUSP00000110327
Ensembl peptide - ENSMUSP00000122648
NCBI entrez gene - 245446     See in Manteia.
MGI - MGI:2442509
RefSeq - XM_017318487
RefSeq - NM_178740
RefSeq - XM_006528011
RefSeq - XM_006528013
RefSeq - XM_017318485
RefSeq - XM_017318486
RefSeq Peptide - NP_848855
swissprot - Q149A4
swissprot - Q810B8
swissprot - B1AU89
Ensembl - ENSMUSG00000046699
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slitrk4ENSDARG00000079781Danio rerio
 SLITRK4ENSGALG00000007242Gallus gallus
 Q8IW52ENSG00000179542Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q810B7 / Slitrk5 / SLIT and NTRK-like protein 5 / O94991* / SLIT and NTRK like family member 5*ENSMUSG0000003321445
Q810C0 / Slitrk2 / SLIT and NTRK-like family, member 2 / O96002* / Q9H156*ENSMUSG0000003679043
Q810B9 / Slitrk3 / Mus musculus SLIT and NTRK-like family, member 3 (Slitrk3), transcript variant 2, mRNA. / O94933* / SLIT and NTRK like family member 3*ENSMUSG0000004830441
Q8C110 / Slitrk6 / SLIT and NTRK-like family, member 6 / Q9H5Y7*ENSMUSG0000004587140
Q810C1 / Slitrk1 / SLIT and NTRK-like family, member 1 / Q96PX8*ENSMUSG0000007547834
Elfn2 / Q68FM6 / Mus musculus leucine rich repeat and fibronectin type III, extracellular 2 (Elfn2), transcript variant 1, mRNA. / Q5R3F8* / extracellular leucine rich repeat and fibronecti...ENSMUSG0000004346015
Elfn1 / Q8C8T7 / Protein ELFN1 / P0C7U0* / extracellular leucine rich repeat and fibronectin type III domain containing 1*ENSMUSG0000004898813
Lrrc19 / Q8BZT5 / Leucine-rich repeat-containing protein 19 / Q9H756* / leucine rich repeat containing 19*ENSMUSG0000004979910


Protein motifs (from Interpro)
Interpro ID Name
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007409 axonogenesis IDA
 biological_processGO:0051965 positive regulation of synapse assembly IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Receptor-type tyrosine-protein phosphatases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000194 hypercalcemia "abnormally high concentration of calcium ions in the circulating blood " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Slc6a3tm1b(KOMP)Wtsi/Slc6a3+
Genetic Background: C57BL/6N-Slc6a3tm1b(KOMP)Wtsi/J

 MP:0002493 increased IgG "greater than normal immunoglobulin class G level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Mthfd1tm2b(KOMP)Wtsi/Mthfd1tm2b(KOMP)Wtsi
Genetic Background: C57BL/6N-Mthfd1tm2b(KOMP)Wtsi/Bay

 MP:0010851 decreased effector memory CD8-positive, alpha-beta T cell number "reduced number of CD8-positive, alpha beta memory T cells with the phenotype CCR7-negative, CD127-positive, CD45RO-positive, and CD25-negative" [CL:0000913, GO_REF:0000031, GOC:add, GOC:pam, PMID:20146720]
Show

Allelic Composition: Slc6a3tm1b(KOMP)Wtsi/Slc6a3+
Genetic Background: C57BL/6N-Slc6a3tm1b(KOMP)Wtsi/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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