ENSMUSG00000033909


Mus musculus

Features
Gene ID: ENSMUSG00000033909
  
Biological name :Usp36
  
Synonyms : B1AQJ2 / ubiquitin specific peptidase 36 / Usp36
  
Possible biological names infered from orthology : Q9P275
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: E2
Gene start: 118259651
Gene end: 118290244
  
Corresponding Affymetrix probe sets: 10393509 (MoGene1.0st)   1455237_at (Mouse Genome 430 2.0 Array)   1456094_at (Mouse Genome 430 2.0 Array)   1458311_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000101903
Ensembl peptide - ENSMUSP00000122761
Ensembl peptide - ENSMUSP00000090036
NCBI entrez gene - 72344     See in Manteia.
MGI - MGI:1919594
RefSeq - XM_011249273
RefSeq - XM_006534302
RefSeq - XM_006534303
RefSeq - XM_006534304
RefSeq - NM_001033528
RefSeq Peptide - NP_001028700
swissprot - B0QZF8
swissprot - B1AQJ2
Ensembl - ENSMUSG00000033909
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 usp36ENSDARG00000032327Danio rerio
 USP36ENSGALG00000037018Gallus gallus
 USP36ENSG00000055483Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Usp42 / B2RQC2 / ubiquitin specific peptidase 42 / Q9H9J4*ENSMUSG0000005130633
G5E8G2 / Usp17ld / ubiquitin specific peptidase 17-like D / C9JLJ4* / A6NCW0* / C9JPN9* / C9JVI0* / D6R901* / D6R9N7* / D6RA61* / D6RBM5* / A6NCW7* / D6RCP7* / D6RJB6* / P0C7H9* / P0C7I0* /...ENSMUSG0000005732116
Usp17lc / ubiquitin specific peptidase 17-like C / C9JJH3* / C9JLJ4* / A6NCW0* / C9JPN9* / C9JVI0* / D6R901* / D6R9N7* / D6RA61* / A6NCW7* / D6RBQ6* / D6RCP7* / D6RJB6* / P0C7H9* / P0C7I0* ...ENSMUSG0000005897616
Q61068 / Usp17la / ubiquitin specific peptidase 17-like A / C9JLJ4* / A6NCW0* / C9JPN9* / C9JVI0* / D6R901* / D6R9N7* / D6RA61* / D6RBM5* / A6NCW7* / D6RCP7* / D6RJB6* / P0C7H9* / P0C7I0* /...ENSMUSG0000005456815
Usp17le / ubiquitin specific peptidase 17-like E / C9JJH3* / C9JLJ4* / A6NCW0* / C9JPN9* / C9JVI0* / D6R901* / D6R9N7* / D6RA61* / A6NCW7* / D6RBQ6* / D6RCP7* / D6RJB6* / P0C7H9* / P0C7I0* ...ENSMUSG0000004307315
E9Q9U0 / Usp17lb / ubiquitin specific peptidase 17-like B / C9JLJ4* / A6NCW0* / C9JPN9* / C9JVI0* / D6R901* / D6R9N7* / D6RA61* / D6RBM5* / A6NCW7* / D6RCP7* / D6RJB6* / P0C7H9* / P0C7I0* /...ENSMUSG0000006236914
Usp49 / Q6P9L4 / ubiquitin specific peptidase 49 / Q70CQ1*ENSMUSG0000009011511
Usp22 / Q5DU02 / ubiquitin specific peptidase 22 / Q9UPT9*ENSMUSG0000004250610
Usp3 / Q91W36 / ubiquitin specific peptidase 3 / Q9Y6I4*ENSMUSG0000003237610
Usp51 / B1AY15 / ubiquitin specific protease 51 / Q70EK9* / ubiquitin specific peptidase 51*ENSMUSG0000006721510
Q8CEG8 / Usp27x / ubiquitin specific peptidase 27, X chromosome / A6NNY8* / ubiquitin specific peptidase 27, X-linked*ENSMUSG000000462699
Usp44 / Q8C2S0 / ubiquitin specific peptidase 44 / Q9H0E7*ENSMUSG000000200205


Protein motifs (from Interpro)
Interpro ID Name
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR018200  Ubiquitin specific protease, conserved site
 IPR028889  Ubiquitin specific protease domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0007000 nucleolus organization ISS
 biological_processGO:0016242 negative regulation of macroautophagy ISS
 biological_processGO:0016578 histone deubiquitination ISS
 biological_processGO:0016579 protein deubiquitination ISO
 biological_processGO:0031647 regulation of protein stability ISS
 biological_processGO:0050821 protein stabilization IMP
 biological_processGO:1903146 regulation of autophagy of mitochondrion ISO
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion ISO
 biological_processGO:2000232 regulation of rRNA processing ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0016607 nuclear speck ISO
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity ISO
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001730 embryonic growth arrest "the cessation of development beyond a particular stage" [J:17509]
Show

Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18+
Genetic Background: involves: C57BL/6J

 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18+
Genetic Background: involves: C57BL/6J

 MP:0010123 increased bone mineral content "elevation in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Usp22tm1b(KOMP)Wtsi/Usp22tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Usp22tm1b(KOMP)Wtsi/Wtsi

 MP:0010124 decreased bone mineral content "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Usp22tm1b(KOMP)Wtsi/Usp22tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Usp22tm1b(KOMP)Wtsi/Wtsi

 MP:0011094 complete embryonic lethality before implantation "death of all organisms of a given genotype in a population between fertilization and implantation (Mus: E0 to less than E4.5)" [MGI:csmith]
Show

Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18+
Genetic Background: involves: C57BL/6J

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Usp22tm1b(KOMP)Wtsi/Usp22tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Usp22tm1b(KOMP)Wtsi/Wtsi

 MP:0012129 failure of blastocyst formation "inability to form a blastocyst from a solid ball of cells known as a morula" [MGI:anna]
Show

Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18+
Genetic Background: involves: C57BL/6J

 MP:0013504 increased embryonic tissue cell apoptosis "increase in the timing or the number of cells in embryonic tissue undergoing programmed cell death" [MGI:csmith]
Show

Allelic Composition: ApcMin/Apc+,Spata18tm1.2Hifa/Spata18+
Genetic Background: involves: C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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