ENSMUSG00000034930


Mus musculus

Features
Gene ID: ENSMUSG00000034930
  
Biological name :Rtkn
  
Synonyms : Q8C6B2 / Rhotekin / Rtkn
  
Possible biological names infered from orthology : Q9BST9
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: C3
Gene start: 83135463
Gene end: 83152579
  
Corresponding Affymetrix probe sets: 10539342 (MoGene1.0st)   1425601_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000116964
Ensembl peptide - ENSMUSP00000112501
Ensembl peptide - ENSMUSP00000120640
Ensembl peptide - ENSMUSP00000148398
Ensembl peptide - ENSMUSP00000122660
Ensembl peptide - ENSMUSP00000065571
Ensembl peptide - ENSMUSP00000085249
NCBI entrez gene - 20166     See in Manteia.
MGI - MGI:107371
RefSeq - XM_006505813
RefSeq - XM_006505805
RefSeq - XM_006505806
RefSeq - XM_006505807
RefSeq - XM_006505808
RefSeq - XM_006505809
RefSeq - XM_006505810
RefSeq - XM_006505811
RefSeq - XM_006505812
RefSeq - NM_001136227
RefSeq - NM_009106
RefSeq - NM_133641
RefSeq Peptide - NP_598396
RefSeq Peptide - NP_001129699
RefSeq Peptide - NP_033132
swissprot - D3Z7S7
swissprot - A0A1D5RLJ9
swissprot - Q8C6B2
swissprot - D3Z4N1
swissprot - D3YXC9
Ensembl - ENSMUSG00000034930
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rtkn2bENSDARG00000052903Danio rerio
 si:dkey-40c11.1ENSDARG00000031345Danio rerio
 RTKNENSG00000114993Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rtkn2 / Q14B46 / Mus musculus rhotekin 2 (Rtkn2), transcript variant 1, mRNA. / Q8IZC4* / rhotekin 2*ENSMUSG0000003784636


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR011072  HR1 rho-binding domain
 IPR011993  PH-like domain superfamily
 IPR012966  Anillin homology domain
 IPR030471  Rhotekin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007266 Rho protein signal transduction IEA
 biological_processGO:0032185 septin cytoskeleton organization IEA
 biological_processGO:0034260 negative regulation of GTPase activity IEA
 biological_processGO:0042981 regulation of apoptotic process ISS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005095 GTPase inhibitor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0017048 Rho GTPase binding IDA
 molecular_functionGO:0017049 GTP-Rho binding IEA


Pathways (from Reactome)
Pathway description
RHO GTPases Activate Rhotekin and Rhophilins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000002233 Rhoc / Q62159 / Rho-related GTP-binding protein RhoC / P08134* / ras homolog family member C*  / complex / reaction
 ENSMUSG00000007815 Rhoa / Q9QUI0 / ras homolog family member A / P61586*  / reaction / complex
 ENSMUSG00000003872 B / Lin7b / O88951 / Q9HAP6* / lin-7 homolog B, crumbs cell polarity complex component*  / reaction / complex
 ENSMUSG00000054364 Rhob / P62746 / ras homolog family member B / P62745*  / reaction / complex
 ENSMUSG00000040158 Q9DBG9 / Tax1bp3 / Tax1-binding protein 3 / O14907*  / complex / reaction






 

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