ENSMUSG00000036510


Mus musculus

Features
Gene ID: ENSMUSG00000036510
  
Biological name :Cdh8
  
Synonyms : Cadherin-8 / Cdh8 / P97291
  
Possible biological names infered from orthology : P55286
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: D1
Gene start: 99024471
Gene end: 99416471
  
Corresponding Affymetrix probe sets: 10580990 (MoGene1.0st)   1422052_at (Mouse Genome 430 2.0 Array)   1441690_at (Mouse Genome 430 2.0 Array)   1455365_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000115977
Ensembl peptide - ENSMUSP00000114507
Ensembl peptide - ENSMUSP00000117326
Ensembl peptide - ENSMUSP00000123619
Ensembl peptide - ENSMUSP00000122493
Ensembl peptide - ENSMUSP00000090935
NCBI entrez gene - 12564     See in Manteia.
MGI - MGI:107434
RefSeq - XM_006530634
RefSeq - NM_001039154
RefSeq - NM_001285913
RefSeq - NM_001285914
RefSeq - NM_007667
RefSeq - XM_006530631
RefSeq Peptide - NP_001272842
RefSeq Peptide - NP_001272843
RefSeq Peptide - NP_031693
RefSeq Peptide - NP_001034243
swissprot - E9PYB2
swissprot - Q8C449
swissprot - P97291
swissprot - D6RG94
swissprot - E9Q451
swissprot - E9PZC1
Ensembl - ENSMUSG00000036510
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CDH8ENSGALG00000005319Gallus gallus
 CDH8ENSG00000150394Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cdh11 / P55288 / Cadherin-11 / P55287*ENSMUSG0000003167365
Cdh7 / Q8BM92 / Cadherin-7 / Q9ULB5*ENSMUSG0000002631258
Cdh10 / P70408 / Cadherin-10 / Q9Y6N8*ENSMUSG0000002232157
Cdh6 / P97326 / Cadherin-6 / P55285*ENSMUSG0000003938556
Cdh20 / Q9Z0M3 / Cadherin-20 / Q9HBT6*ENSMUSG0000005084056
Cdh18 / cadherin 18 / Q13634*ENSMUSG0000004042055
Cdh12 / Q5RJH3 / Cadherin-12 / P55289*ENSMUSG0000004045255
Cdh9 / cadherin 9 / Q9ULB4*ENSMUSG0000002537054
Cdh24 / Q6PFX6 / Cadherin-24 / Q86UP0*ENSMUSG0000005967453
Cdh22 / Q9WTP5 / Cadherin-22 / Q9UJ99*ENSMUSG0000005316649
Cdh19 / cadherin 19, type 2 / Q9H159* / cadherin 19*ENSMUSG0000004721641


Protein motifs (from Interpro)
Interpro ID Name
 IPR000233  Cadherin, cytoplasmic domain
 IPR002126  Cadherin
 IPR015919  Cadherin-like
 IPR020894  Cadherin conserved site
 IPR027397  Catenin binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IEA
 biological_processGO:0007268 chemical synaptic transmission IMP
 biological_processGO:0009409 response to cold IMP
 biological_processGO:0035249 synaptic transmission, glutamatergic IMP
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043083 synaptic cleft IDA
 cellular_componentGO:0043679 axon terminus IDA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Adherens junctions interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001391 abnormal tail movements "a change from the normal manner of moving the tail" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Notch1tm3(cre)Rko/Notch1tm3(cre)Rko
Genetic Background: involves: 129X1/SvJ * C57BL/6J * SJL

 MP:0002206 abnormal CNS synaptic transmission "defect in the communication from a neuron to a target across a synapse in the central nervous system" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Notch1tm3(cre)Rko/Notch1tm3(cre)Rko
Genetic Background: involves: 129X1/SvJ * C57BL/6J * SJL

 MP:0002733 abnormal thermal nociception "abnormal capability to sense pain elicited by thermal stimulation" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Notch1tm3(cre)Rko/Notch1tm3(cre)Rko
Genetic Background: involves: 129X1/SvJ * C57BL/6J * SJL

 MP:0004753 abnormal miniature excitatory postsynaptic currents "defect in the size or duration of spontaneous currents detected in postsynaptic cells that occur in the absence of an excitatory impulse" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Notch1tm3(cre)Rko/Notch1tm3(cre)Rko
Genetic Background: involves: 129X1/SvJ * C57BL/6J * SJL

 MP:0006073 abnormal retinal bipolar cell morphology "anomalous structure of the cells that transmit signals from the photoreceptors to retinal amacrine and ganglion cells" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:92623:]
Show

Allelic Composition: Saa3tm1(KOMP)Vlcg/Saa3+
Genetic Background: involves: C57BL/6NTac

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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