ENSMUSG00000040420


Mus musculus

Features
Gene ID: ENSMUSG00000040420
  
Biological name :Cdh18
  
Synonyms : cadherin 18 / Cdh18
  
Possible biological names infered from orthology : Q13634
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: A2
Gene start: 22549022
Gene end: 23474418
  
Corresponding Affymetrix probe sets: 10423274 (MoGene1.0st)   10423287 (MoGene1.0st)   1458120_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000130851
Ensembl peptide - ENSMUSP00000153905
Ensembl peptide - ENSMUSP00000128011
Ensembl peptide - ENSMUSP00000128643
Ensembl peptide - ENSMUSP00000129170
NCBI entrez gene - 320865     See in Manteia.
MGI - MGI:1344366
RefSeq - XM_011245360
RefSeq - XM_006520094
RefSeq - XM_006520095
RefSeq - XM_006520096
RefSeq - XM_006520097
RefSeq - XM_006520098
RefSeq - NM_001081299
RefSeq Peptide - NP_001074768
swissprot - F6RSC2
swissprot - E9Q941
swissprot - E9Q9Q6
swissprot - Q8BLB5
Ensembl - ENSMUSG00000040420
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CDH18ENSDARG00000102769Danio rerio
 CDH18ENSGALG00000036097Gallus gallus
 CDH18ENSG00000145526Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cdh7 / Q8BM92 / Cadherin-7 / Q9ULB5*ENSMUSG0000002631260
Cdh11 / P55288 / Cadherin-11 / P55287*ENSMUSG0000003167358
Cdh10 / P70408 / Cadherin-10 / Q9Y6N8*ENSMUSG0000002232158
Cdh9 / cadherin 9 / Q9ULB4*ENSMUSG0000002537057
Cdh12 / Q5RJH3 / Cadherin-12 / P55289*ENSMUSG0000004045257
Cdh6 / P97326 / Cadherin-6 / P55285*ENSMUSG0000003938556
Cdh20 / Q9Z0M3 / Cadherin-20 / Q9HBT6*ENSMUSG0000005084056
Cdh8 / P97291 / Cadherin-8 / P55286*ENSMUSG0000003651055
Cdh22 / Q9WTP5 / Cadherin-22 / Q9UJ99*ENSMUSG0000005316652
Cdh24 / Q6PFX6 / Cadherin-24 / Q86UP0*ENSMUSG0000005967451
Cdh19 / cadherin 19, type 2 / Q9H159* / cadherin 19*ENSMUSG0000004721643


Protein motifs (from Interpro)
Interpro ID Name
 IPR000233  Cadherin, cytoplasmic domain
 IPR002126  Cadherin
 IPR015919  Cadherin-like
 IPR020894  Cadherin conserved site
 IPR027397  Catenin binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IEA
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Adherens junctions interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002183 gliosis "increased growth pattern of neuroglia in a damaged area of the brain or spinal cord" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Tg(APPV717F)109Ili/0,Tg(GFAP-APOE_i2)14Hol/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA

 MP:0006058 decreased cerebral infarction size "decreased size of necrotic area of the cerebrum resulting from a sudden insufficiency of arterial or venous blood supply " [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Apoetm1Unc/Apoetm1Unc,Tg(APPV717F)109Ili/0,Tg(GFAP-APOE_i2)14Hol/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA

 MP:0008916 abnormal astrocyte physiology "any functional anomaly of one of the large neuroglia cells of nervous tissue" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Mtmr2tm1Ueli/Mtmr2tm1Ueli,Sbf2Gt(XH212)Byg/Sbf2Gt(XH212)Byg
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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