Manteia

ENSMUSG00000038762

Mus musculus

Features

Gene ID:	ENSMUSG00000038762

Biological name :	Abcf1

Synonyms :	Abcf1 / ATP-binding cassette, sub-family F (GCN20), member 1 / Q6P542

Possible biological names infered from orthology :	ATP binding cassette subfamily F member 1 / Q8NE71

Species:	Mus musculus

Chr. number:	17
Strand:	-1
Band:	B1
Gene start:	35956819
Gene end:	35969761

Corresponding Affymetrix probe sets:	10450648 (MoGene1.0st) 1420157_s_at (Mouse Genome 430 2.0 Array) 1420158_s_at (Mouse Genome 430 2.0 Array) 1426921_at (Mouse Genome 430 2.0 Array) 1427444_at (Mouse Genome 430 2.0 Array) 1452236_at (Mouse Genome 430 2.0 Array) 1452429_s_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000036881 Ensembl peptide - ENSMUSP00000134092 Ensembl peptide - ENSMUSP00000134716 NCBI entrez gene - 224742 See in Manteia. MGI - MGI:1351658 RefSeq - XM_006524122 RefSeq - NM_013854 RefSeq Peptide - NP_038882 swissprot - G3UYI0 swissprot - Q6P542 swissprot - G3V012 Ensembl - ENSMUSG00000038762

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Abcf3 / Q8K268 / ATP-binding cassette, sub-family F (GCN20), member 3 / Q9NUQ8* / ATP binding cassette subfamily F member 3*	ENSMUSG00000003234	32

Protein motifs (from Interpro)

Interpro ID	Name
IPR003439	ABC transporter-like
IPR003593	AAA+ ATPase domain
IPR011989	Armadillo-like helical
IPR017871	ABC transporter, conserved site
IPR027417	P-loop containing nucleoside triphosphate hydrolase
IPR032781	ABC-transporter extension domain

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006413	translational initiation	ISO
biological_process	GO:0045727	positive regulation of translation	ISO
cellular_component	GO:0005634	nucleus	IEA
cellular_component	GO:0005635	nuclear envelope	ISS
cellular_component	GO:0005654	nucleoplasm	ISS
cellular_component	GO:0005737	cytoplasm	ISS
cellular_component	GO:0005829	cytosol	IEA
cellular_component	GO:0005840	ribosome	IEA
cellular_component	GO:0042788	polysomal ribosome	ISS
molecular_function	GO:0000166	nucleotide binding	IEA
molecular_function	GO:0005524	ATP binding	ISO
molecular_function	GO:0008494	translation activator activity	ISS
molecular_function	GO:0016887	ATPase activity	IEA
molecular_function	GO:0043022	ribosome binding	ISO

Pathways (from Reactome)

Pathway description

ABC-family proteins mediated transport

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0013292	embryonic lethality prior to organogenesis	"death prior to the completion of embryo turning (Mus: E9-9.5)" [MGI:smb]	Show Allelic Composition: Fabp4^tm1Brsp/Fabp4^tm1Brsp,Fabp5^tm1Hota/Fabp5^tm1Hota Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * SJL

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSMUSG00000069049	Q9Z0N2 / Eif2s3y / Eukaryotic translation initiation factor 2 subunit 3, Y-linked / EIF2S3* / P41091* / Q2VIR3* / EIF2S3B* / eukaryotic translation initiation factor 2 subunit gamma* / euk...	/ reaction / complex
ENSMUSG00000074656	Eif2s2 / Q99L45 / Eukaryotic translation initiation factor 2 subunit 2 / P20042* / eukaryotic translation initiation factor 2 subunit beta*	/ complex / reaction
ENSMUSG00000035150	Q9Z0N1 / Eif2s3x / Eukaryotic translation initiation factor 2 subunit 3, X-linked / EIF2S3* / P41091* / Q2VIR3* / EIF2S3B* / eukaryotic translation initiation factor 2 subunit gamma* / euk...	/ complex / reaction
ENSMUSG00000021116	Eif2s1 / Q6ZWX6 / Eukaryotic translation initiation factor 2 subunit 1 / P05198* / eukaryotic translation initiation factor 2 subunit alpha*	/ reaction / complex

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr