ENSMUSG00000038943


Mus musculus

Features
Gene ID: ENSMUSG00000038943
  
Biological name :Prc1
  
Synonyms : Prc1 / protein regulator of cytokinesis 1 / Q99K43
  
Possible biological names infered from orthology : O43663
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: D2
Gene start: 80294450
Gene end: 80316259
  
Corresponding Affymetrix probe sets: 10554445 (MoGene1.0st)   1423774_a_at (Mouse Genome 430 2.0 Array)   1423775_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000134548
Ensembl peptide - ENSMUSP00000043379
Ensembl peptide - ENSMUSP00000129675
Ensembl peptide - ENSMUSP00000133295
Ensembl peptide - ENSMUSP00000133387
Ensembl peptide - ENSMUSP00000133618
Ensembl peptide - ENSMUSP00000133817
Ensembl peptide - ENSMUSP00000133910
Ensembl peptide - ENSMUSP00000134262
Ensembl peptide - ENSMUSP00000134282
NCBI entrez gene - 233406     See in Manteia.
MGI - MGI:1858961
RefSeq - XM_006540857
RefSeq - NM_001285997
RefSeq - NM_001285998
RefSeq - NM_145150
RefSeq - XM_006540855
RefSeq - XM_006540856
RefSeq Peptide - NP_001272927
RefSeq Peptide - NP_660132
RefSeq Peptide - NP_001272926
swissprot - Q99K43
swissprot - G3UW86
swissprot - G3UXB1
swissprot - G3UXT4
swissprot - G3UY19
swissprot - G3UYX6
swissprot - G3UZL8
swissprot - G3UYZ3
swissprot - G3XA79
swissprot - G3UWQ7
Ensembl - ENSMUSG00000038943
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prc1aENSDARG00000100918Danio rerio
 prc1bENSDARG00000005993Danio rerio
 ENSGALG00000043144Gallus gallus
 PRC1ENSGALG00000012836Gallus gallus
 PRC1ENSG00000198901Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007145  Microtubule-associated protein, MAP65/Ase1/PRC1
 IPR032921  Protein regulator of cytokinesis 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000226 microtubule cytoskeleton organization IEA
 biological_processGO:0000910 cytokinesis IEA
 biological_processGO:0001578 microtubule bundle formation IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0008284 positive regulation of cell proliferation ISS
 biological_processGO:0032465 regulation of cytokinesis ISS
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0000922 spindle pole IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005819 spindle ISO
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0030496 midbody ISO
 cellular_componentGO:0070938 contractile ring ISS
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0019894 kinesin binding ISO
 molecular_functionGO:0019901 protein kinase binding ISO
 molecular_functionGO:0042802 identical protein binding ISO


Pathways (from Reactome)
Pathway description
RHO GTPases activate CIT


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0008762 embryonic lethality "death of an animal in the embryonic period (Mus: up to E14)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Bach2m2Anu/Bach2m2Anu
Genetic Background: C57BL/6NCrlAnu-Bach2m2Anu

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000002233 Rhoc / Q62159 / Rho-related GTP-binding protein RhoC / P08134* / ras homolog family member C*  / reaction / complex
 ENSMUSG00000007815 Rhoa / Q9QUI0 / ras homolog family member A / P61586*  / reaction / complex
 ENSMUSG00000041498 Kif14 / L0N7N1 / Kinesin-like protein KIF14 / Q15058* / kinesin family member 14*  / reaction / complex
 ENSMUSG00000054364 Rhob / P62746 / ras homolog family member B / P62745*  / complex / reaction
 ENSMUSG00000001847 Rac1 / P63001 / RAS-related C3 botulinum substrate 1 / P63000* / Rac family small GTPase 1*  / reaction / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr