ENSMUSG00000039089


Mus musculus

Features
Gene ID: ENSMUSG00000039089
  
Biological name :L3mbtl3
  
Synonyms : L3mbtl3 / Mus musculus L3MBTL3 histone methyl-lysine binding protein (L3mbtl3), transcript variant 3, mRNA. / Q8BLB7
  
Possible biological names infered from orthology : L3MBTL3, histone methyl-lysine binding protein / Q96JM7
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: A4
Gene start: 26274468
Gene end: 26375971
  
Corresponding Affymetrix probe sets: 10368380 (MoGene1.0st)   1434246_at (Mouse Genome 430 2.0 Array)   1443030_at (Mouse Genome 430 2.0 Array)   1454882_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000037619
Ensembl peptide - ENSMUSP00000101158
Ensembl peptide - ENSMUSP00000133479
NCBI entrez gene - 237339     See in Manteia.
MGI - MGI:2143628
RefSeq - XM_017313935
RefSeq - NM_001347467
RefSeq - NM_001359254
RefSeq - NM_172787
RefSeq - XM_006512734
RefSeq - XM_006512735
RefSeq - XM_011243171
RefSeq - XM_011243172
RefSeq - XM_006512731
RefSeq - XM_006512732
RefSeq - XM_006512733
RefSeq Peptide - NP_001346183
RefSeq Peptide - NP_766375
RefSeq Peptide - NP_001334396
swissprot - Q8BLB7
Ensembl - ENSMUSG00000039089
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 l3mbtl3ENSDARG00000025983Danio rerio
 L3MBTL3ENSGALG00000034030Gallus gallus
 Q96JM7ENSG00000198945Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A2A5N8 / L3mbtl1 / Lethal(3)malignant brain tumor-like protein 1 / Q9Y468* / L3MBTL1, histone methyl-lysine binding protein*ENSMUSG0000003557637
L3mbtl4 / lethal(3)malignant brain tumor-like protein 4 / Q8NA19* / L3MBTL4, histone methyl-lysine binding protein*ENSMUSG0000004156532
Sfmbt2 / Scm-like with four mbt domains 2 / Q5VUG0*ENSMUSG0000006118617
P59178 / L3mbtl2 / Lethal(3)malignant brain tumor-like protein 2 / Q969R5* / L3MBTL2, polycomb repressive complex 1 subunit*ENSMUSG0000002239417
Q9JMD1 / Sfmbt1 / Scm-like with four MBT domains protein 1 / Q9UHJ3* / Scm like with four mbt domains 1*ENSMUSG0000000652717
Mbtd1 / Q6P5G3 / MBT domain-containing protein 1 / Q05BQ5* / mbt domain containing 1*ENSMUSG0000005947415
Scmh1 / Q8K214 / Polycomb protein SCMH1 / Q96GD3* / Scm polycomb group protein homolog 1*ENSMUSG0000000008515
Scml2 / Scm polycomb group protein like 2 / Q9UQR0*ENSMUSG0000000003711
Scml4 / Q80VG1 / Scm polycomb group protein like 4 / Q8N228*ENSMUSG000000447706


Protein motifs (from Interpro)
Interpro ID Name
 IPR001660  Sterile alpha motif domain
 IPR002515  Zinc finger, C2HC-type
 IPR004092  Mbt repeat
 IPR013761  Sterile alpha motif/pointed domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0030099 myeloid cell differentiation IMP
 biological_processGO:0030225 macrophage differentiation IMP
 biological_processGO:0030851 granulocyte differentiation IMP
 biological_processGO:0043249 erythrocyte maturation IDA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005730 nucleolus IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001577 anemia "less than normal levels of red blood cells, hemoglobin or volume of packed red blood cells " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]
Show

Allelic Composition: Ift172wim/Ift172wim
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

 MP:0002123 abnormal hematopoiesis "abnormal development of the enucleated fetal and adult erythrocytes that develop in the aorta, genital ridge and mesonephros region and later in the fetal and adult liver" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ift172wim/Ift172wim
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

 MP:0011089 complete perinatal lethality "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
Show

Allelic Composition: Ift172wim/Ift172wim
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr