ENSMUSG00000044646


Mus musculus

Features
Gene ID: ENSMUSG00000044646
  
Biological name :Zbtb7c
  
Synonyms : Q8VCZ7 / Zbtb7c / zinc finger and BTB domain containing 7C
  
Possible biological names infered from orthology : A1YPR0
  
Species: Mus musculus
  
Chr. number: 18
Strand: 1
Band: E3
Gene start: 75820178
Gene end: 76148561
  
Corresponding Affymetrix probe sets: 10456756 (MoGene1.0st)   1425819_at (Mouse Genome 430 2.0 Array)   1433019_at (Mouse Genome 430 2.0 Array)   1436365_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000057856
Ensembl peptide - ENSMUSP00000126808
NCBI entrez gene - 207259     See in Manteia.
MGI - MGI:2443302
RefSeq - XM_006525737
RefSeq - NM_145356
RefSeq Peptide - NP_663331
RefSeq Peptide - NP_001344435
swissprot - Q8VCZ7
Ensembl - ENSMUSG00000044646
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zbtb7cENSDARG00000100985Danio rerio
 ZBTB7CENSGALG00000033408Gallus gallus
 A1YPR0ENSG00000184828Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O88939 / Zbtb7a / zinc finger and BTB domain containing 7a / O95365*ENSMUSG0000003501135
Q64321 / Zbtb7b / zinc finger and BTB domain containing 7B / O15156*ENSMUSG0000002804235
Hic1 / HIC ZBTB transcriptional repressor 1 / Q14526*ENSMUSG0000004309919
Q9WUK6 / Zbtb18 / zinc finger and BTB domain containing 18 / Q99592*ENSMUSG0000006365916
Hic2 / Q9JLZ6 / Hypermethylated in cancer 2 protein / Q96JB3* / HIC ZBTB transcriptional repressor 2*ENSMUSG0000005024016
Zbtb5 / Q7TQG0 / zinc finger and BTB domain containing 5 / O15062*ENSMUSG0000004965716
Q8BID6 / Zbtb46 / zinc finger and BTB domain containing 46 / Q86UZ6*ENSMUSG0000002758316
Zbtb3 / Q91X45 / zinc finger and BTB domain containing 3 / Q9H5J0*ENSMUSG0000007166115
Q811H0 / Zbtb42 / zinc finger and BTB domain containing 42 / B2RXF5*ENSMUSG0000003763814
Zbtb8b / zinc finger and BTB domain containing 8b / Q8NAP8* / AL033529.1*ENSMUSG0000004848513
Zbtb10 / zinc finger and BTB domain containing 10 / Q96DT7*ENSMUSG0000006911412
Q9CWH1 / Zbtb8a / zinc finger and BTB domain containing 8a / Q96BR9*ENSMUSG0000002880712


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR013087  Zinc finger C2H2-type
 IPR016024  Armadillo-type fold
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008285 negative regulation of cell proliferation ISO
 biological_processGO:0045600 positive regulation of fat cell differentiation IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding IDA
 cellular_componentGO:0005634 nucleus IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000352 decreased cell proliferation "less than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Fbn1tm3.2Lysa/Fbn1+
Genetic Background: Not Specified

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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