ENSMUSG00000048062


Mus musculus

Features
Gene ID: ENSMUSG00000048062
  
Biological name :Fpr-rs4
  
Synonyms : A4FUQ5 / Formyl peptide receptor-related sequence 4 / Fpr-rs4
  
Possible biological names infered from orthology : formyl peptide receptor 3 / FPR3 / P25089
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: A3.2
Gene start: 18021733
Gene end: 18022704
  
Corresponding Affymetrix probe sets: 10442104 (MoGene1.0st)   1422358_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000093311
NCBI entrez gene - 14291     See in Manteia.
MGI - MGI:1278317
RefSeq - NM_008041
RefSeq Peptide - NP_032067
swissprot - A4FUQ5
Ensembl - ENSMUSG00000048062
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FPR3ENSG00000187474Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O88537 / Fpr-rs3 / Formyl peptide receptor-related sequence 3 / FPR3* / P25089* / formyl peptide receptor 3*ENSMUSG0000006070182
Q3SXG2 / Fpr-rs6 / Formyl peptide receptor-related sequence 6 / FPR3* / P25089* / formyl peptide receptor 3*ENSMUSG0000007127574
Q71MR7 / Fpr-rs7 / Formyl peptide receptor-related sequence 7 / FPR3* / P25089* / formyl peptide receptor 3*ENSMUSG0000007127673
Fpr2 / O88536 / Formyl peptide receptor 2 / P25090*ENSMUSG0000005227070
Fpr3 / O08790 / Formyl peptide receptor-related sequence 1 / FPR2* / P25090* / formyl peptide receptor 2*ENSMUSG0000007970068
Fpr1 / P33766 / fMet-Leu-Phe receptor / P21462* / formyl peptide receptor 1*ENSMUSG0000004555157
Cmklr1 / P97468 / Mus musculus chemokine-like receptor 1 (Cmklr1), transcript variant 1, mRNA. / Q99788* / chemerin chemokine-like receptor 1*ENSMUSG0000004219034
C3ar1 / O09047 / C3a anaphylatoxin chemotactic receptor / Q16581* / complement C3a receptor 1*ENSMUSG0000004055233
Gpr1 / Q8K087 / G-protein coupled receptor 1 / P46091*ENSMUSG0000004685631
Ptgdr2 / Q9Z2J6 / Prostaglandin D2 receptor 2 / Q9Y5Y4*ENSMUSG0000003411731
Gpr33 / O88416 / Probable G-protein coupled receptor 33 / Q49SQ1* / G protein-coupled receptor 33 (gene/pseudogene)*ENSMUSG0000003514829
C5ar1 / P30993 / C5a anaphylatoxin chemotactic receptor 1 / P21730* / complement C5a receptor 1*ENSMUSG0000004913028
Gpr152 / Q8BXS7 / G protein-coupled receptor 152 / Q8TDT2*ENSMUSG0000004472424
C5ar2 / complement component 5a receptor 2 / Q9P296*ENSMUSG0000007436124


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000826  Formyl peptide receptor-related
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002430 complement receptor mediated signaling pathway IBA
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IBA
 biological_processGO:0050900 leukocyte migration IBA
 biological_processGO:0060326 cell chemotaxis IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004875 complement receptor activity IBA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004982 N-formyl peptide receptor activity IDA


Pathways (from Reactome)
Pathway description
G alpha (i) signalling events
Formyl peptide receptors bind formyl peptides and many other ligands


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000024659 Anxa1 / P10107 / Annexin A1 / P04083*  / complex / reaction
 ENSMUSG00000042770 Hebp1 / heme binding protein 1 / Q9NRV9*  / reaction / complex






 

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contact: otassy@igbmc.fr