ENSMUSG00000056481


Mus musculus

Features
Gene ID: ENSMUSG00000056481
  
Biological name :Cd248
  
Synonyms : Cd248 / Endosialin / Q91V98
  
Possible biological names infered from orthology : CD248 molecule / Q9HCU0
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: A
Gene start: 5068078
Gene end: 5070637
  
Corresponding Affymetrix probe sets: 10460541 (MoGene1.0st)   1417439_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000070847
NCBI entrez gene - 70445     See in Manteia.
MGI - MGI:1917695
RefSeq - NM_054042
RefSeq Peptide - NP_473383
swissprot - Q91V98
Ensembl - ENSMUSG00000056481
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cd248aENSDARG00000103713Danio rerio
 cd248bENSDARG00000077938Danio rerio
 CD248ENSG00000174807Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cd93 / O89103 / Complement component C1q receptor / Q9NPY3* / CD93 molecule*ENSMUSG0000002743519
Thbd / P15306 / thrombomodulin / P07204*ENSMUSG0000007474318
Q6NZL8 / Scube1 / signal peptide, CUB domain, EGF-like 1 / Q8IWY4* / signal peptide, CUB domain and EGF like domain containing 1*ENSMUSG0000001676314
Q66PY1 / Scube3 / Signal peptide, CUB and EGF-like domain-containing protein 3 / Q8IX30* / signal peptide, CUB domain and EGF like domain containing 3*ENSMUSG0000003867714
Q9JJS0 / Scube2 / Signal peptide, CUB and EGF-like domain-containing protein 2 / Q9NQ36* / signal peptide, CUB domain and EGF like domain containing 2*ENSMUSG0000000727912
Matn2 / O08746 / Mus musculus matrilin 2 (Matn2), transcript variant 1, mRNA. / O00339* / matrilin 2*ENSMUSG0000002232411
Q8VCP9 / Clec14a / C-type lectin domain family 14 member A / Q86T13* / C-type lectin domain containing 14A*ENSMUSG0000004593011
Matn4 / matrilin 4 / O95460*ENSMUSG0000001699510
Matn3 / O35701 / Matrilin-3 / O15232*ENSMUSG000000205838
Matn1 / P51942 / Cartilage matrix protein / P21941* / matrilin 1, cartilage matrix protein*ENSMUSG000000405336
Vwa1 / Q8R2Z5 / von Willebrand factor A domain containing 1 / Q6PCB0*ENSMUSG000000421164


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001304  C-type lectin-like
 IPR001881  EGF-like calcium-binding domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR018097  EGF-like calcium-binding, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0016477 cell migration IMP
 biological_processGO:0048535 lymph node development IMP
 biological_processGO:0060033 anatomical structure regression IMP
 biological_processGO:2000353 positive regulation of endothelial cell apoptotic process IMP
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0050840 extracellular matrix binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ighmtm1.1Aak/Ighmtm1.1Aak
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0003447 reduced tumor growth/size "less than expected development of tumorous growth when compared to controls" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:65383]
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Allelic Composition: Runx1tm1.1Medv/Runx1tm1.1Medv
Genetic Background: involves: 129P2/OlaHsd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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