Manteia

ENSMUSG00000061068

Mus musculus

Features

Gene ID:	ENSMUSG00000061068

Biological name :	Mcpt4

Synonyms :	mast cell protease 4 / Mcpt4

Possible biological names infered from orthology :

Species:	Mus musculus

Chr. number:	14
Strand:	-1
Band:	C3
Gene start:	56059629
Gene end:	56062313

Corresponding Affymetrix probe sets:	10420247 (MoGene1.0st) 1425967_a_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000038103 NCBI entrez gene - 17227 See in Manteia. MGI - MGI:96940 RefSeq - NM_010779 RefSeq Peptide - NP_034909 swissprot - Q3UN88 Ensembl - ENSMUSG00000061068

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Mcpt1 / P11034 / Mast cell protease 1	ENSMUSG00000022227	78
Cma2 / chymase 2, mast cell	ENSMUSG00000068289	71
Mcpt9 / O35164 / Mast cell protease 9	ENSMUSG00000071361	70
Mcpt2 / P15119 / mast cell protease 2	ENSMUSG00000022226	66
Cma1 / P21844 / Chymase / P23946* / chymase 1*	ENSMUSG00000022225	58
Gzmf / P08883 / Granzyme F / GZMH* / P20718* / granzyme H*	ENSMUSG00000015441	49
Gzmb / P04187 / granzyme B / P10144*	ENSMUSG00000015437	49
Ctsg / P28293 / cathepsin G / P08311*	ENSMUSG00000040314	49
Gzmg / P13366 / granzyme G / GZMH* / P20718* / granzyme H*	ENSMUSG00000040284	48
Gzme / P08884 / Granzyme E / GZMH* / P20718* / granzyme H*	ENSMUSG00000022156	48
Gzmc / P08882 / Granzyme C / GZMB* / P10144* / granzyme B*	ENSMUSG00000079186	48
Gzmn / granzyme N / GZMH* / P20718* / granzyme H*	ENSMUSG00000015443	46
Gzmd / P11033 / Granzyme D / GZMH* / P20718* / granzyme H*	ENSMUSG00000059256	46
Mcpt8 / P43430 / Mast cell protease 8	ENSMUSG00000022157	43
Gzmk / O35205 / Granzyme K / P49863*	ENSMUSG00000042385	37
Gzma / P11032 / Granzyme A / P12544*	ENSMUSG00000023132	37
Prss57 / Q14B24 / Serine protease 57 / Q6UWY2*	ENSMUSG00000020323	37
Gzmm / granzyme M isoform 2 / P51124* / granzyme M*	ENSMUSG00000054206	37
Cfd / P03953 / Complement factor D / P00746*	ENSMUSG00000061780	33

Protein motifs (from Interpro)

Interpro ID	Name
IPR001254	Serine proteases, trypsin domain
IPR001314	Peptidase S1A, chymotrypsin family
IPR009003	Peptidase S1, PA clan
IPR018114	Serine proteases, trypsin family, histidine active site
IPR033116	Serine proteases, trypsin family, serine active site

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006508	proteolysis	IEA
molecular_function	GO:0004252	serine-type endopeptidase activity	IEA
molecular_function	GO:0008233	peptidase activity	IEA
molecular_function	GO:0008236	serine-type peptidase activity	IEA
molecular_function	GO:0016787	hydrolase activity	IEA

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0002423	abnormal mast cell physiology	"anomalous response of the granulated cells found in most tissues and which contain large amounts of histamine and heparin in granules" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Adam15^tm1Bbl/Adam15^tm1Bbl Genetic Background: B6.129X1-Adam15^tm1Bbl
MP:0002551	abnormal blood coagulation	"altered ability or inability of the blood to clot" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Adam15^tm1Bbl/Adam15^tm1Bbl Genetic Background: B6.129X1-Adam15^tm1Bbl

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr