ENSMUSG00000066148


Mus musculus

Features
Gene ID: ENSMUSG00000066148
  
Biological name :Prpf4
  
Synonyms : pre-mRNA processing factor 4 / Prpf4 / Q9DAW6
  
Possible biological names infered from orthology : O43172
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: B3
Gene start: 62408797
Gene end: 62426990
  
Corresponding Affymetrix probe sets: 10505282 (MoGene1.0st)   1429724_at (Mouse Genome 430 2.0 Array)   1438481_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000081572
NCBI entrez gene - 70052     See in Manteia.
MGI - MGI:1917302
RefSeq - NM_027297
RefSeq Peptide - NP_081573
swissprot - Q059T9
swissprot - Q9DAW6
Ensembl - ENSMUSG00000066148
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prpf4ENSDARG00000067639Danio rerio
 PRPF4ENSGALG00000008857Gallus gallus
 PRPF4ENSG00000136875Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Prpf19 / Q99KP6 / Pre-mRNA-processing factor 19 / Q9UMS4*ENSMUSG0000002473519
Q8K450 / Spag16 / Sperm-associated antigen 16 protein / Q8N0X2* / sperm associated antigen 16*ENSMUSG0000005315319


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR014906  Pre-mRNA processing factor 4 (PRP4)-like
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat
 IPR027106  U4/U6 small nuclear ribonucleoprotein Prp4
 IPR036285  PRP4-like superfamily
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome ISO
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0008380 RNA splicing IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005681 spliceosomal complex IEA
 cellular_componentGO:0015030 Cajal body IEA
 cellular_componentGO:0016607 nuclear speck ISO
 cellular_componentGO:0046540 U4/U6 x U5 tri-snRNP complex IEA
 cellular_componentGO:0071001 U4/U6 snRNP ISS
 cellular_componentGO:0097525 spliceosomal snRNP complex ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0017070 U6 snRNA binding IBA
 molecular_functionGO:0030621 U4 snRNA binding IBA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000015748 Prpf3 / Q922U1 / U4/U6 small nuclear ribonucleoprotein Prp3 / O43395* / pre-mRNA processing factor 3*  / complex
 ENSMUSG00000060288 Ppih / Q9D868 / Peptidyl-prolyl cis-trans isomerase H   / complex






 

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