ENSMUSG00000071347


Mus musculus

Features
Gene ID: ENSMUSG00000071347
  
Biological name :C1qtnf9
  
Synonyms : C1qtnf9 / Complement C1q and tumor necrosis factor-related protein 9 / Q4ZJN1
  
Possible biological names infered from orthology : B2RNN3 / C1q and TNF related 9 / C1q and TNF related 9B / C1QTNF9B / P0C862
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: D1
Gene start: 60768134
Gene end: 60780869
  
Corresponding Affymetrix probe sets: 10415737 (MoGene1.0st)   1442033_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000025940
NCBI entrez gene - 239126     See in Manteia.
MGI - MGI:3045252
RefSeq - NM_183175
RefSeq Peptide - NP_898998
swissprot - Q4ZJN1
Ensembl - ENSMUSG00000071347
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 c1qtnf9ENSDARG00000058318Danio rerio
 ENSGALG00000017117Gallus gallus
 B2RNN3ENSG00000205863Homo sapiens
 P0C862ENSG00000240654Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Otol1 / Q4ZJM7 / Otolin-1 / A6NHN0*ENSMUSG0000002778844
Col8a2 / P25318 / Collagen alpha-2(VIII) chain / P25067* / collagen type VIII alpha 2 chain*ENSMUSG0000005617443
Q05306 / Col10a1 / Collagen alpha-1(X) chain / Q03692* / collagen type X alpha 1 chain*ENSMUSG0000003946242
Col8a1 / Q00780 / Collagen alpha-1(VIII) chain Vastatin / P27658* / collagen type VIII alpha 1 chain*ENSMUSG0000006819641
Q9D8U4 / C1qtnf2 / Complement C1q tumor necrosis factor-related protein 2 / Q9BXJ5* / C1q and TNF related 2*ENSMUSG0000004649133
Adipoq / Q60994 / Adiponectin / Q15848* / adiponectin, C1Q and collagen domain containing*ENSMUSG0000002287832
Q8BVD7 / C1qtnf7 / Complement C1q tumor necrosis factor-related protein 7 / Q9BXJ2* / C1q and TNF related 7*ENSMUSG0000006153532
C1qb / P14106 / Complement C1q subcomponent subunit B / P02746* / complement C1q B chain*ENSMUSG0000003690529
Q8K479 / C1qtnf5 / Complement C1q tumor necrosis factor-related protein 5 / Q9BXJ0* / C1q and TNF related 5*ENSMUSG0000007959229
C1qc / Q02105 / Complement C1q subcomponent subunit C / P02747* / complement C1q C chain*ENSMUSG0000003689628


Protein motifs (from Interpro)
Interpro ID Name
 IPR001073  C1q domain
 IPR008160  Collagen triple helix repeat
 IPR008983  Tumour necrosis factor-like domain superfamily
 IPR016133  Insect cysteine-rich antifreeze protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0019395 fatty acid oxidation IEA
 biological_processGO:0071902 positive regulation of protein serine/threonine kinase activity IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005581 collagen trimer IEA
 molecular_functionGO:0005179 hormone activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000609 abnormal liver physiology "aberrant function of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Grhl3tm1Bogi/Grhl3+
Genetic Background: involves: C57BL/6 * C57BL/6J

 MP:0000759 abnormal skeletal muscle morphology "anomalous structure of any of the striated muscle fibers connected at either or both extremeties with the bony framework of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Grhl3tm1Bogi/Grhl3+
Genetic Background: involves: C57BL/6 * C57BL/6J

 MP:0001260 increased body weight "greater than normal average weight " [J:33400]
Show

Allelic Composition: Grhl3tm1Bogi/Grhl3+
Genetic Background: involves: C57BL/6 * C57BL/6J

 MP:0001261 obese "excessively fat; an increase in fat in the subcutaneous connective tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
Show

Allelic Composition: Grhl3tm1Bogi/Grhl3+
Genetic Background: involves: C57BL/6 * C57BL/6J

 MP:0002079 increased circulating insulin level "greater than normal levels of insulin in blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Grhl3tm1Bogi/Grhl3+
Genetic Background: involves: C57BL/6 * C57BL/6J

 MP:0002106 abnormal muscle physiology "anomolous function of the muscle, not due to an anatomical defect" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Grhl3tm1Bogi/Grhl3+
Genetic Background: involves: C57BL/6 * C57BL/6J

 MP:0002628 fatty liver "an accumulation of fat deposits in the liver " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Grhl3tm1Bogi/Grhl3+
Genetic Background: involves: C57BL/6 * C57BL/6J

 MP:0003058 increased insulin secretion "greater than normal release of this hormone secreted by beta cells of the pancreas, that promotes glucose utilization, protein synthesis, and the formation and storage of neutral lipids " [MeSH:National Library of Medicine - Medical Subject Headings, 2003, RGD:Rat Genome Database submission]
Show

Allelic Composition: Grhl3tm1Bogi/Grhl3+
Genetic Background: involves: C57BL/6 * C57BL/6J

 MP:0003961 decreased lean body mass "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
Show

Allelic Composition: Grhl3tm1Bogi/Grhl3+
Genetic Background: involves: C57BL/6 * C57BL/6J

 MP:0005331 insulin resistance "diminished effectiveness of insulin in lowering plasma glucose levels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:84260, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Grhl3tm1Bogi/Grhl3+
Genetic Background: involves: C57BL/6 * C57BL/6J

 MP:0005418 abnormal circulating hormone level "anomalous blood concentration of any of the chemical substances that have specific regulatory effects on the activity of a certain organ or organs; originally applied to substances secreted by various endocrine glands and transported in the bloodstream to the target organs, it is sometimes extended to include substances that are not produced by the endocrine glands but that have similar effects" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Grhl3tm1Bogi/Grhl3+
Genetic Background: involves: C57BL/6 * C57BL/6J

 MP:0005458 increased percent body fat "more fat, relative to the norm, as a percentage of total body weight" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Grhl3tm1Bogi/Grhl3+
Genetic Background: involves: C57BL/6 * C57BL/6J

 MP:0005645 abnormal hypothalamus physiology "anomalous function of the ventral and medial region of the diencephalon forming the walls of the ventral half of the third ventricle, which is normally involved in the functions of the autonomic (visceral motor) nervous system and, through its vascular link with the anterior lobe of the pituitary gland, in endocrine mechanisms" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Grhl3tm1Bogi/Grhl3+
Genetic Background: involves: C57BL/6 * C57BL/6J

 MP:0005669 increased circulating leptin level "greater than the normal blood concentration of the peptide hormone secreted by white adipocytes and believed to regulate food intake and energy balance" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, J:34751]
Show

Allelic Composition: Grhl3tm1Bogi/Grhl3+
Genetic Background: involves: C57BL/6 * C57BL/6J

 MP:0009355 increased liver triglyceride level "higher than normal concentration of triacylglycerols in the liver" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Grhl3tm1Bogi/Grhl3+
Genetic Background: involves: C57BL/6 * C57BL/6J

 MP:0011939 increased food intake "increase in the total number of calories/food amount taken in over time when compared to the normal state" [MGI:csmith]
Show

Allelic Composition: Grhl3tm1Bogi/Grhl3+
Genetic Background: involves: C57BL/6 * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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