ENSMUSG00000036905


Mus musculus

Features
Gene ID: ENSMUSG00000036905
  
Biological name :C1qb
  
Synonyms : C1qb / Complement C1q subcomponent subunit B / P14106
  
Possible biological names infered from orthology : complement C1q B chain / P02746
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: D3
Gene start: 136880129
Gene end: 136886187
  
Corresponding Affymetrix probe sets: 10517508 (MoGene1.0st)   1417063_at (Mouse Genome 430 2.0 Array)   1434366_x_at (Mouse Genome 430 2.0 Array)   1437726_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000040246
NCBI entrez gene - 12260     See in Manteia.
MGI - MGI:88224
RefSeq - NM_009777
RefSeq Peptide - NP_033907
swissprot - P14106
Ensembl - ENSMUSG00000036905
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 c1qbENSDARG00000044612Danio rerio
 C1QBENSGALG00000004771Gallus gallus
 C1QBENSG00000173369Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
C1qc / Q02105 / Complement C1q subcomponent subunit C / P02747* / complement C1q C chain*ENSMUSG0000003689645
Q4ZJN1 / C1qtnf9 / Complement C1q and tumor necrosis factor-related protein 9 / B2RNN3* / P0C862* / C1QTNF9B* / C1q and TNF related 9* / C1q and TNF related 9B*ENSMUSG0000007134738
Q8BVD7 / C1qtnf7 / Complement C1q tumor necrosis factor-related protein 7 / Q9BXJ2* / C1q and TNF related 7*ENSMUSG0000006153537
Col8a2 / P25318 / Collagen alpha-2(VIII) chain / P25067* / collagen type VIII alpha 2 chain*ENSMUSG0000005617436
Otol1 / Q4ZJM7 / Otolin-1 / A6NHN0*ENSMUSG0000002778836
Col8a1 / Q00780 / Collagen alpha-1(VIII) chain Vastatin / P27658* / collagen type VIII alpha 1 chain*ENSMUSG0000006819636
Q9D8U4 / C1qtnf2 / Complement C1q tumor necrosis factor-related protein 2 / Q9BXJ5* / C1q and TNF related 2*ENSMUSG0000004649134
Q05306 / Col10a1 / Collagen alpha-1(X) chain / Q03692* / collagen type X alpha 1 chain*ENSMUSG0000003946234
Q8K479 / C1qtnf5 / Complement C1q tumor necrosis factor-related protein 5 / Q9BXJ0* / C1q and TNF related 5*ENSMUSG0000007959234
Adipoq / Q60994 / Adiponectin / Q15848* / adiponectin, C1Q and collagen domain containing*ENSMUSG0000002287833


Protein motifs (from Interpro)
Interpro ID Name
 IPR001073  C1q domain
 IPR008160  Collagen triple helix repeat
 IPR008983  Tumour necrosis factor-like domain superfamily
 IPR016133  Insect cysteine-rich antifreeze protein
 IPR037573  Complement C1q subcomponent B


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006958 complement activation, classical pathway IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0048839 inner ear development IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005581 collagen trimer IEA
 cellular_componentGO:0005615 extracellular space IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IDA


Pathways (from Reactome)
Pathway description
Initial triggering of complement
Classical antibody-mediated complement activation
Regulation of Complement cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000023224 P97290 / Serping1 / serine (or cysteine) peptidase inhibitor, clade G, member 1 / P05155* / serpin family G member 1*  / complex / reaction
 ENSMUSG00000055172 C1ra / Q8CG16 / Complement C1r-A subcomponent Complement C1r-A subcomponent heavy chain Complement C1r-A subcomponent light chain / C1R* / P00736* / complement C1r*  / complex
 ENSMUSG00000037942 Crp / P14847 / C-reactive protein / P02741*  / complex
 ENSMUSG00000036887 C1qa / P98086 / Complement C1q subcomponent subunit A / P02745* / complement C1q A chain*  / complex
 ENSMUSG00000079343 C1s2 / Q8CFG8 / complement component 1, s subcomponent 2 / C1S* / P09871* / complement C1s*  / complex
 ENSMUSG00000024371 C2 / P21180 / Complement C2 Complement C2b fragment Complement C2a fragment / P06681* / complement C2*  / reaction
 ENSMUSG00000036905 C1qb / P14106 / Complement C1q subcomponent subunit B / P02746* / complement C1q B chain*  / complex
 ENSMUSG00000073418 C4b / P01029 / Complement C4-B Complement C4 beta chain Complement C4 alpha chain C4a anaphylatoxin Complement C4 gamma chain / C4A* / P0C0L4* / P0C0L5* / complement C4B (Chido blood group)...  / reaction
 ENSMUSG00000038521 C1s1 / complement component 1, s subcomponent 1 / C1S* / P09871* / complement C1s*  / complex
 ENSMUSG00000036896 C1qc / Q02105 / Complement C1q subcomponent subunit C / P02747* / complement C1q C chain*  / complex
 ENSMUSG00000098470 C1rb / Q8CFG9 / Complement C1r-B subcomponent Complement C1r-B subcomponent heavy chain Complement C1r-B subcomponent light chain / C1R* / P00736* / complement C1r*  / complex






 

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