ENSMUSG00000027078


Mus musculus

Features
Gene ID: ENSMUSG00000027078
  
Biological name :Ube2l6
  
Synonyms : Q9QZU9 / Ube2l6 / ubiquitin-conjugating enzyme E2L 6
  
Possible biological names infered from orthology : O14933
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: D
Gene start: 84798828
Gene end: 84810335
  
Corresponding Affymetrix probe sets: 10473356 (MoGene1.0st)   1417172_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000119507
Ensembl peptide - ENSMUSP00000099702
NCBI entrez gene - 56791     See in Manteia.
MGI - MGI:1914500
RefSeq - NM_019949
RefSeq Peptide - NP_064333
swissprot - A2ATR9
swissprot - Q9QZU9
Ensembl - ENSMUSG00000027078
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 O14933ENSG00000156587Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P68037 / Ube2l3 / ubiquitin-conjugating enzyme E2L 3ENSMUSG0000003896550
Q6ZWY6 / Ube2d2b / ubiquitin-conjugating enzyme E2D 2BENSMUSG0000006344733
P61080 / Ube2d1 / ubiquitin-conjugating enzyme E2D 1 / P51668*ENSMUSG0000001992731
P62838 / Ube2d2a / ubiquitin-conjugating enzyme E2D 2A / UBE2D2* / P62837* / ubiquitin conjugating enzyme E2 D2*ENSMUSG0000009189631
Ube2dnl1ENSMUSG0000005043529
P52482 / Ube2e1 / ubiquitin-conjugating enzyme E2E 1 / P51965*ENSMUSG0000002177428
P52483 / Ube2e3 / ubiquitin-conjugating enzyme E2E 3 / Q969T4*ENSMUSG0000002701127
Ube2dnl2 / ubiquitin-conjugating enzyme E2D N-terminal like 2ENSMUSG0000004707927
Q91W82 / Ube2e2 / ubiquitin-conjugating enzyme E2E 2 / Q96LR5*ENSMUSG0000005831727
P61079 / Ube2d3 / ubiquitin-conjugating enzyme E2D 3 / P61077*ENSMUSG0000007857827
Ube2s / Q921J4 / ubiquitin-conjugating enzyme E2S / Q16763*ENSMUSG0000006086023


Protein motifs (from Interpro)
Interpro ID Name
 IPR000608  Ubiquitin-conjugating enzyme E2
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like
 IPR023313  Ubiquitin-conjugating enzyme, active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0019941 modification-dependent protein catabolic process IDA
 biological_processGO:0032020 ISG15-protein conjugation IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019787 ubiquitin-like protein transferase activity IDA
 molecular_functionGO:0042296 ISG15 transferase activity IDA
 molecular_functionGO:0043130 ubiquitin binding ISO


Pathways (from Reactome)
Pathway description
ISG15 antiviral mechanism
Termination of translesion DNA synthesis
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000000751 Rpa1 / Q8VEE4 / Replication protein A 70 kDa DNA-binding subunit / P27694* / replication protein A1*  / complex / reaction
 ENSMUSG00000012483 Rpa3 / Q9CQ71 / Replication protein A 14 kDa subunit / P35244* / replication protein A3*  / complex / reaction
 ENSMUSG00000025580 Eif4a3 / Q91VC3 / Eukaryotic initiation factor 4A-III Eukaryotic initiation factor 4A-III, N-terminally processed / P38919* / eukaryotic translation initiation factor 4A3*  / reaction
 ENSMUSG00000023953 Polh / Q9JJN0 / DNA polymerase eta / Q9Y253*  / complex / reaction
 ENSMUSG00000021668 Polk / Q9QUG2 / polymerase (DNA directed), kappa / Q9UBT6* / DNA polymerase kappa*  / complex / reaction
 ENSMUSG00000026082 Rev1 / Q920Q2 / DNA repair protein REV1 / Q9UBZ9* / REV1, DNA directed polymerase*  / complex / reaction
 ENSMUSG00000038425 Poli / polymerase (DNA directed), iota / Q9UNA4* / DNA polymerase iota*  / complex / reaction
 ENSMUSG00000093661 Eif4e3 / Q9DBB5 / Eukaryotic translation initiation factor 4E type 3 / Q8N5X7* / eukaryotic translation initiation factor 4E family member 3*  / reaction
 ENSMUSG00000032596 Uba7 / ubiquitin-like modifier activating enzyme 7 / P41226*  / reaction
 ENSMUSG00000027342 Pcna / P17918 / proliferating cell nuclear antigen / P12004*  / complex / reaction
 ENSMUSG00000025278 Flnb / Q80X90 / Filamin-B / O75369*  / reaction
 ENSMUSG00000045983 Eif4g1 / Q6NZJ6 / Eukaryotic translation initiation factor 4 gamma 1 / Q04637*  / reaction
 ENSMUSG00000094973 Gm8994 / EIF4A3* / P38919* / eukaryotic translation initiation factor 4A3*  / reaction
 ENSMUSG00000035692 Isg15 / Q64339 / Ubiquitin-like protein ISG15 / P05161* / ISG15 ubiquitin-like modifier*  / complex / reaction
 ENSMUSG00000059796 Eif4a1 / P60843 / Eukaryotic initiation factor 4A-I / P60842* / eukaryotic translation initiation factor 4A1*  / reaction
 ENSMUSG00000028884 Rpa2 / replication protein A2 / P15927*  / complex / reaction
 ENSMUSG00000000275 Q61510 / Trim25 / E3 ubiquitin/ISG15 ligase TRIM25 / Q14258* / tripartite motif containing 25*  / complex
 ENSMUSG00000003184 Irf3 / P70671 / interferon regulatory factor 3 / Q14653*  / reaction
 ENSMUSG00000025234 Arih1 / Q9Z1K5 / E3 ubiquitin-protein ligase ARIH1 / Q9Y4X5* / ariadne RBR E3 ubiquitin protein ligase 1*  / complex / reaction
 ENSMUSG00000021774 P52482 / Ube2e1 / ubiquitin-conjugating enzyme E2E 1 / P51965*  / reaction
 ENSMUSG00000026254 Eif4e2 / Q8BMB3 / Mus musculus eukaryotic translation initiation factor 4E member 2 (Eif4e2), transcript variant 4, mRNA. / O60573* / eukaryotic translation initiation factor 4E family member 2*  / complex / reaction
 ENSMUSG00000061130 Ppm1b / P36993 / protein phosphatase 1B, magnesium dependent, beta isoform / O75688* / protein phosphatase, Mg2+/Mn2+ dependent 1B*  / reaction






 

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