ENSDARG00000000563


Danio rerio

Features
Gene ID: ENSDARG00000000563
  
Biological name :ttn.1
  
Synonyms : titin, tandem duplicate 1 / ttn.1
  
Possible biological names infered from orthology : A2ASS6 / Q8WZ42 / titin / TTN
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 42732992
Gene end: 42873700
  
Corresponding Affymetrix probe sets: Dr.1662.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000107866
Ensembl peptide - ENSDARP00000145605
Ensembl peptide - ENSDARP00000157573
swissprot - G1K2X0
ZFIN ID - ZDB-GENE-030616-413
Ensembl - ENSDARG00000000563
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TTNENSG00000155657Homo sapiens
 TtnENSMUSG00000051747Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ttn.2 / titin, tandem duplicate 2 / TTN* / titin* / A2ASS6* / Q8WZ42*ENSDARG0000002821359
hmcn1 / hemicentin 1 / D3YXG0* / Q96RW7*ENSDARG000000169363
hmcn2 / hemicentin 2 / A2AJ76* / Q8NDA2*ENSDARG000000793272
obsl1b / obscurin-like 1b / OBSL1* / D3YYU8* / O75147* / obscurin like 1* / Obscurin-like protein 1 *ENSDARG000000773881
obsl1a / obscurin-like 1a / OBSL1* / O75147* / obscurin like 1*ENSDARG000000036841
CU928131.1ENSDARG000001092621
obscnb / obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF b / OBSCN* / Q5VST9* / obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF*ENSDARG000000221011
mxra5b / matrix-remodelling associated 5b / MXRA5* / Q9NR99* / matrix remodeling associated 5*ENSDARG000000763091
igsf10 / immunoglobulin superfamily, member 10 / Q3V1M1* / Q6WRI0*ENSDARG000000774971
si:ch211-159i8.4ENSDARG000000763321
mxra5a / matrix-remodelling associated 5a / MXRA5* / Q9NR99* / matrix remodeling associated 5*ENSDARG000000748151
palld / palladin, cytoskeletal associated protein / Q8WX93* / Q9ET54* / Palladin *ENSDARG000000400091
hmcn2 / hemicentin 2ENSDARG000000860600
myot / myotilinENSDARG000000763120


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR008266  Tyrosine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007519 skeletal muscle tissue development IGI
 biological_processGO:0014866 skeletal myofibril assembly IMP
 biological_processGO:0030239 myofibril assembly IGI
 biological_processGO:0048769 sarcomerogenesis IMP
 biological_processGO:0071688 striated muscle myosin thick filament assembly IGI
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
Striated Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000037 anatomical structure anatomical structure increased amount , abnormal
anatomical structure decreased amount , abnormal
anatomical structure amount , ameliorated
Show

 ZFA:0000076 swim bladder swim bladder uninflated , abnormal
Show

 ZFA:0000114 heart heart edematous , abnormal
Show

 ZFA:0000155 somite somite skeletal muscle cell disorganized , abnormal
somite myofibril disorganized , abnormal
somite sarcomere disorganized , abnormal
somite Z disc disorganized , abnormal
somite sarcomere spatial pattern , abnormal
somite Z disc spatial pattern , abnormal
Show

 ZFA:0000851 somite 12 somite 12 sarcomere decreased length , abnormal
somite 12 myosin filament decreased length , abnormal
somite 12 myosin filament disorganized , abnormal
Show

 ZFA:0000852 somite 15 somite 15 myosin filament disorganized , abnormal
Show

 ZFA:0000982 somite 6 somite 6 sarcomere decreased length , abnormal
somite 6 Z disc decreased width , abnormal
somite 6 myosin filament decreased length , abnormal
somite 6 myosin filament decreased width , abnormal
Show

 ZFA:0001056 myotome myotome sarcomere spatial pattern , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased size , abnormal
whole organism decreased behavioural activity , abnormal
whole organism decreased life span , abnormal
Show

 ZFA:0005277 skeletal muscle skeletal muscle sarcomere disorganized , abnormal
Show

 ZFA:0009115 skeletal muscle cell skeletal muscle cell nucleus shape , abnormal
skeletal muscle cell myofibril disorganized , abnormal
skeletal muscle cell Z disc disorganized , abnormal
skeletal muscle cell A band disorganized , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr