ENSDARG00000007561


Danio rerio

Features
Gene ID: ENSDARG00000007561
  
Biological name :cdh23
  
Synonyms : cadherin-related 23 / cdh23
  
Possible biological names infered from orthology : Cadherin-23 / Q99PF4 / Q9H251
  
Species: Danio rerio
  
Chr. number: 13
Strand: 1
Band:
Gene start: 43050562
Gene end: 43213012
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000026525
swissprot - F1QUS2
ZFIN ID - ZDB-GENE-040513-7
Ensembl - ENSDARG00000007561
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000004653Gallus gallus
 ENSGALG00000036824Gallus gallus
 CDH23ENSG00000107736Homo sapiens
 Cdh23ENSMUSG00000012819Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
fat1a / FAT atypical cadherin 1a / FAT1* / Q14517* / FAT atypical cadherin 1*ENSDARG0000001759127
fat3a / FAT atypical cadherin 3a / FAT3* / Q8TDW7* / FAT atypical cadherin 3*ENSDARG0000003384026
fat2 / FAT atypical cadherin 2 / Q5F226* / Q9NYQ8* / Protocadherin Fat 2 *ENSDARG0000001892326
fat1b / FAT atypical cadherin 1b / FAT1* / Q14517* / FAT atypical cadherin 1*ENSDARG0000001906326
FAT3 (1 of many) / si:ch211-214k5.6 / FAT3* / Q8TDW7* / FAT atypical cadherin 3*ENSDARG0000008770925
dchs1a / dachsous cadherin-related 1a / DCHS1* / Q96JQ0* / E9PVD3* / Protocadherin-16 * / dachsous cadherin-related 1*ENSDARG0000007002524
dchs1b / dachsous cadherin-related 1b / DCHS1* / Q96JQ0* / E9PVD3* / Protocadherin-16 * / dachsous cadherin-related 1*ENSDARG0000007985023
FAT4 / FAT atypical cadherin 4 / Q2PZL6* / Q6V0I7* / Protocadherin Fat 4 *ENSDARG0000010528522
si:ch211-186j3.6ENSDARG0000007808817
si:dkey-22o22.2ENSDARG0000010244516
celsr2 / cadherin, EGF LAG seven-pass G-type receptor 2 / Q9HCU4* / cadherin EGF LAG seven-pass G-type receptor 2 isoform 2 *ENSDARG0000001972614
celsr1b / cadherin EGF LAG seven-pass G-type receptor 1b / CELSR1* / O35161* / Q9NYQ6* / cadherin EGF LAG seven-pass G-type receptor 1*ENSDARG0000005825914
celsr1a / cadherin EGF LAG seven-pass G-type receptor 1a / CELSR1* / O35161* / Q9NYQ6* / cadherin EGF LAG seven-pass G-type receptor 1*ENSDARG0000006918514
celsr3 / cadherin, EGF LAG seven-pass G-type receptor 3 / Q91ZI0* / Q9NYQ7*ENSDARG0000005582511
si:dkey-1m11.6ENSDARG0000009786910
cdh23 / cadherin-related 23 / Q99PF4* / Q9H251* / Cadherin-23 *ENSDARG000000944540


Protein motifs (from Interpro)
Interpro ID Name
 IPR002126  Cadherin
 IPR015919  Cadherin-like
 IPR020894  Cadherin conserved site
 IPR033030  Cadherin-23


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IMP
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IEA
 biological_processGO:0007605 sensory perception of sound IMP
 biological_processGO:0007626 locomotory behavior IEA
 biological_processGO:0030030 cell projection organization IMP
 biological_processGO:0035315 hair cell differentiation IMP
 biological_processGO:0035678 neuromast hair cell morphogenesis IMP
 biological_processGO:0042891 antibiotic transport IEA
 biological_processGO:0050957 equilibrioception IMP
 biological_processGO:0050974 detection of mechanical stimulus involved in sensory perception IMP
 biological_processGO:0060117 auditory receptor cell development IMP
 biological_processGO:0060122 inner ear receptor cell stereocilium organization IEA
 biological_processGO:0061512 protein localization to cilium IMP
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005929 cilium IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISS
 cellular_componentGO:0032420 stereocilium IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0042895 antibiotic transmembrane transporter activity IMP


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000107 eye eye edematous , abnormal
eye decreased size , abnormal
Show

 ZFA:0000168 anterior macula anterior macula stereocilium bundle bent , abnormal
anterior macula stereocilium bundle splayed , abnormal
Show

 ZFA:0000217 inner ear inner ear stereocilium bundle disorganized , abnormal
inner ear stereocilium bundle splayed , abnormal
Show

 ZFA:0000282 sensory system sensory system quality , abnormal
Show

 ZFA:0000396 nervous system nervous system quality , abnormal
Show

 ZFA:0000445 optic tectum optic tectum necrotic , abnormal
Show

 ZFA:0000678 hair cell anterior macula hair cell anterior macula apoptotic process increased occurrence , abnormal
hair cell anterior macula stereocilium decreased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism unbalanced , abnormal
whole organism decreased behavioural activity , abnormal
whole organism circling , abnormal
whole organism shape , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved , abnormal
post-vent region quality , abnormal
post-vent region morphology , abnormal
Show

 ZFA:0001338 intestine intestine edematous , abnormal
Show

 ZFA:0009121 auditory receptor cell auditory receptor cell stereocilium bundle splayed , abnormal
Show

 ZFA:0009238 afferent neuron afferent neuron has extra parts of type afferent neuron neuron projection, abnormal
afferent neuron neuron projection development process quality , abnormal
afferent neuron neuron projection complexity , abnormal
afferent neuron neuron projection transient , abnormal
Show

 ZFA:0009366 hair cell hair cell stereocilium bundle splayed , abnormal
Show

 ZFA:0009367 neuromast hair cell neuromast hair cell plasma membrane protruding , abnormal
neuromast hair cell physical object quality , abnormal
neuromast hair cell morphology , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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