ENSDARG00000019726


Danio rerio

Features
Gene ID: ENSDARG00000019726
  
Biological name :celsr2
  
Synonyms : cadherin, EGF LAG seven-pass G-type receptor 2 / celsr2
  
Possible biological names infered from orthology : cadherin EGF LAG seven-pass G-type receptor 2 isoform 2 / Q9HCU4
  
Species: Danio rerio
  
Chr. number: 22
Strand: 1
Band:
Gene start: 413349
Gene end: 465663
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000123500
Ensembl peptide - ENSDARP00000076888
NCBI entrez gene - 560426     See in Manteia.
RefSeq - NM_001080577
RefSeq Peptide - NP_001074046
swissprot - F1QT64
swissprot - F1QEP4
ZFIN ID - ZDB-GENE-070122-2
Ensembl - ENSDARG00000019726
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000042961Gallus gallus
 ENSGALG00000032750Gallus gallus
 CELSR2ENSG00000143126Homo sapiens
 Celsr2ENSMUSG00000068740Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
celsr1a / cadherin EGF LAG seven-pass G-type receptor 1a / CELSR1* / O35161* / Q9NYQ6* / cadherin EGF LAG seven-pass G-type receptor 1*ENSDARG0000006918555
celsr1b / cadherin EGF LAG seven-pass G-type receptor 1b / CELSR1* / O35161* / Q9NYQ6* / cadherin EGF LAG seven-pass G-type receptor 1*ENSDARG0000005825955
celsr3 / cadherin, EGF LAG seven-pass G-type receptor 3 / Q91ZI0* / Q9NYQ7*ENSDARG0000005582542
fat1a / FAT atypical cadherin 1a / FAT1* / Q14517* / FAT atypical cadherin 1*ENSDARG0000001759119
fat3a / FAT atypical cadherin 3a / FAT3* / Q8TDW7* / FAT atypical cadherin 3*ENSDARG0000003384019
FAT3 (1 of many) / si:ch211-214k5.6 / FAT3* / Q8TDW7* / FAT atypical cadherin 3*ENSDARG0000008770918
fat2 / FAT atypical cadherin 2 / Q5F226* / Q9NYQ8* / Protocadherin Fat 2 *ENSDARG0000001892317
fat1b / FAT atypical cadherin 1b / FAT1* / Q14517* / FAT atypical cadherin 1*ENSDARG0000001906317
dchs1b / dachsous cadherin-related 1b / DCHS1* / Q96JQ0* / E9PVD3* / Protocadherin-16 * / dachsous cadherin-related 1*ENSDARG0000007985017
dchs1a / dachsous cadherin-related 1a / DCHS1* / Q96JQ0* / E9PVD3* / Protocadherin-16 * / dachsous cadherin-related 1*ENSDARG0000007002516
FAT4 / FAT atypical cadherin 4 / Q2PZL6* / Q6V0I7* / Protocadherin Fat 4 *ENSDARG0000010528515
cdh23 / cadherin-related 23 / Q9H251*ENSDARG0000000756113
si:ch211-186j3.6ENSDARG0000007808813
si:dkey-22o22.2ENSDARG0000010244512
si:dkey-1m11.6ENSDARG0000009786910
cdh23 / cadherin-related 23 / Q99PF4* / Q9H251* / Cadherin-23 *ENSDARG000000944542


Protein motifs (from Interpro)
Interpro ID Name
 IPR000203  GPS motif
 IPR000742  EGF-like domain
 IPR000832  GPCR, family 2, secretin-like
 IPR001791  Laminin G domain
 IPR001879  GPCR, family 2, extracellular hormone receptor domain
 IPR001881  EGF-like calcium-binding domain
 IPR002049  Laminin EGF domain
 IPR002126  Cadherin
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR013032  EGF-like, conserved site
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR015919  Cadherin-like
 IPR017981  GPCR, family 2-like
 IPR020894  Cadherin conserved site
 IPR032471  GAIN domain, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0008104 protein localization IGI
 biological_processGO:0021754 facial nucleus development IMP
 biological_processGO:0055113 epiboly involved in gastrulation with mouth forming second IGI
 biological_processGO:0098609 cell-cell adhesion IMP
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000111 germ ring germ ring closure incomplete , abnormal
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 ZFA:0000135 notochord notochord decreased length , abnormal
Show

 ZFA:0000206 facial nerve motor nucleus facial nerve motor nucleus mislocalised , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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