ENSDARG00000010792


Danio rerio

Features
Gene ID: ENSDARG00000010792
  
Biological name :cdc25b
  
Synonyms : cdc25b / cell division cycle 25B
  
Possible biological names infered from orthology : CDC25A / cell division cycle 25A / M-phase inducer phosphatase 1 / M-phase inducer phosphatase 2 / P30304 / P30305 / P30306 / P48964
  
Species: Danio rerio
  
Chr. number: 13
Strand: -1
Band:
Gene start: 14915344
Gene end: 14929236
  
Corresponding Affymetrix probe sets: Dr.25673.1.S1_at (Zebrafish Array)   Dr.25673.2.S1_at (Zebrafish Array)   Dr.8228.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000003494
Ensembl peptide - ENSDARP00000118347
NCBI entrez gene - 57925     See in Manteia.
RefSeq - NM_001115095
RefSeq Peptide - NP_001108567
swissprot - B8JKA6
swissprot - B8A5N7
ZFIN ID - ZDB-GENE-000330-5
Ensembl - ENSDARG00000010792
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CDC25AENSGALG00000038469Gallus gallus
 CDC25AENSG00000164045Homo sapiens
 CDC25BENSG00000101224Homo sapiens
 Cdc25aENSMUSG00000032477Mus musculus
 Cdc25bENSMUSG00000027330Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cdc25d / cell division cycle 25 homolog dENSDARG0000007559919


Protein motifs (from Interpro)
Interpro ID Name
 IPR000751  M-phase inducer phosphatase
 IPR001763  Rhodanese-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0009794 regulation of mitotic cell cycle, embryonic IMP
 biological_processGO:0010389 regulation of G2/M transition of mitotic cell cycle IMP
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0045931 positive regulation of mitotic cell cycle IMP
 biological_processGO:1902751 positive regulation of cell cycle G2/M phase transition IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA


Pathways (from Reactome)
Pathway description
Activation of ATR in response to replication stress
Cyclin E associated events during G1/S transition
Cyclin A/B1/B2 associated events during G2/M transition
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
Cyclin A:Cdk2-associated events at S phase entry


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0001094 whole organism whole organism shape , abnormal
whole organism dead , abnormal
whole organism lethal (sensu genetics) , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001117 post-vent region post-vent region segmentation arrested , abnormal
Show

 ZFA:0001477 portion of tissue portion of tissue necrotic , abnormal
Show

 ZFA:0009090 pigment cell pigment cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000026577 cdk2 / cyclin-dependent kinase 2 / P24941* / P97377*  / reaction
 ENSDARG00000087554 cdk1 / cyclin-dependent kinase 1 / P06493* / P11440*  / reaction
 ENSDARG00000104765 chek1 / checkpoint kinase 1 / O14757* / O35280* / Serine/threonine-protein kinase Chk1 *  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr