ENSGALG00000038469


Gallus gallus

Features
Gene ID: ENSGALG00000038469
  
Biological name :CDC25A
  
Synonyms : CDC25A / cell division cycle 25A
  
Possible biological names infered from orthology : M-phase inducer phosphatase 1 / P30304 / P48964
  
Species: Gallus gallus
  
Chr. number: 2
Strand: 1
Band:
Gene start: 569650
Gene end: 582544
  
Corresponding Affymetrix probe sets: GgaAffx.3075.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000057880
NCBI entrez gene - 420375     See in Manteia.
RefSeq - NM_001199572
RefSeq - XM_015281061
RefSeq Peptide - NP_001186501
swissprot - A0A1D5PY31
Ensembl - ENSGALG00000038469
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdc25bENSDARG00000010792Danio rerio
 CDC25AENSG00000164045Homo sapiens
 Cdc25aENSMUSG00000032477Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000751  M-phase inducer phosphatase
 IPR001763  Rhodanese-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0009314 response to radiation IEA
 biological_processGO:0034644 cellular response to UV IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:1902751 positive regulation of cell cycle G2/M phase transition IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0051087 chaperone binding IEA


Pathways (from Reactome)
Pathway description
Activation of ATR in response to replication stress
Cyclin E associated events during G1/S transition
Cyclin A/B1/B2 associated events during G2/M transition
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
Cyclin A:Cdk2-associated events at S phase entry


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000005695 CHEK2 / checkpoint kinase 2 / O96017* / Q9Z265* / Serine/threonine-protein kinase Chk2 *  / reaction
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / complex
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / complex
 ENSGALG00000040794 CCNE2 / cyclin E2 / O96020* / Q9Z238* / G1/S-specific cyclin-E2 *  / reaction
 ENSGALG00000003085 CDK1 / cyclin-dependent kinase 1 / P06493* / P11440*  / reaction
 ENSGALG00000042418 CHEK1 / Q8AYC9 / Serine/threonine-protein kinase Chk1 / O14757* / O35280* / checkpoint kinase 1*  / reaction






 

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