ENSDARG00000011989


Danio rerio

Features
Gene ID: ENSDARG00000011989
  
Biological name :crx
  
Synonyms : cone-rod homeobox / crx
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 36932718
Gene end: 36936443
  
Corresponding Affymetrix probe sets: Dr.14325.1.S1_at (Zebrafish Array)   NM_152940_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000030526
NCBI entrez gene - 81881     See in Manteia.
RefSeq - NM_152940
RefSeq Peptide - NP_694419
swissprot - Q8JIZ3
ZFIN ID - ZDB-GENE-010403-1
Ensembl - ENSDARG00000011989
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
otx5 / orthodenticle homolog 5ENSDARG0000004348373
otx2b / Q91981 / orthodenticle homeobox 2b / OTX2* / P32243* / orthodenticle homeobox 2*ENSDARG0000001123565
otx1 / Q91994 / orthodenticle homeobox 1 / P32242* / P80205* / Homeobox protein OTX1 *ENSDARG0000009499262
otx2a / Q90267 / orthodenticle homeobox 2aENSDARG0000003070358
dmbx1b / Q566X8 / diencephalon/mesencephalon homeobox 1b / DMBX1* / Q8NFW5* / diencephalon/mesencephalon homeobox 1*ENSDARG0000000251028
Q8JI10 / dmbx1a / diencephalon/mesencephalon homeobox 1a / DMBX1* / Q91ZK4* / Q8NFW5* / diencephalon/mesencephalon homeobox 1* / Diencephalon/mesencephalon homeobox protein 1 *ENSDARG0000000992227
pitx1 / paired-like homeodomain 1 / PITX3* / P78337* / O75364* / paired like homeodomain 3*ENSDARG0000011660822
pitx3 / Q6QU75 / paired-like homeodomain 3ENSDARG0000007006922
pitx2 / Q9W5Z2 / paired-like homeodomain 2 / P97474* / Q99697* / paired-like homeodomain transcription factor 2*ENSDARG0000003619421
mixl1 / Mix paired-like homeobox / Q9H2W2* / Q9WUI0* / Homeobox protein MIXL1 *ENSDARG0000006925219
prrx1b / paired related homeobox 1b / PRRX1* / P63013* / P54821* / paired related homeobox 1* / Paired mesoderm homeobox protein 1 *ENSDARG0000004202719
prrx1a / paired related homeobox 1a / PRRX1* / P63013* / P54821* / paired related homeobox 1* / Paired mesoderm homeobox protein 1 *ENSDARG0000003397119
pax10 / paired box 10ENSDARG0000005336418
zgc:101100ENSDARG0000002195917
gsc / goosecoid / P56915* / Q02591* / goosecoid homeobox* / Homeobox protein goosecoid *ENSDARG0000005907315


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR003025  Transcription factor Otx
 IPR009057  Homeobox-like domain superfamily
 IPR013851  Transcription factor Otx, C-terminal
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001654 eye development IMP
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007601 visual perception IMP
 biological_processGO:0030182 neuron differentiation IMP
 biological_processGO:0042462 eye photoreceptor cell development IMP
 biological_processGO:0046671 negative regulation of retinal cell programmed cell death IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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