ENSDARG00000059073


Danio rerio

Features
Gene ID: ENSDARG00000059073
  
Biological name :gsc
  
Synonyms : goosecoid / gsc
  
Possible biological names infered from orthology : goosecoid homeobox / Homeobox protein goosecoid / P56915 / Q02591
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 19343015
Gene end: 19345521
  
Corresponding Affymetrix probe sets: Dr.289.1.S1_a_at (Zebrafish Array)   NM_131017_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000076522
Ensembl peptide - ENSDARP00000116722
NCBI entrez gene - 30212     See in Manteia.
RefSeq - NM_131017
RefSeq Peptide - NP_571092
swissprot - Q7ZZR4
swissprot - Q7ZZR5
ZFIN ID - ZDB-GENE-980528-2060
Ensembl - ENSDARG00000059073
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GSCENSGALG00000010974Gallus gallus
 GSCENSG00000133937Homo sapiens
 GscENSMUSG00000021095Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pax10 / paired box 10ENSDARG0000005336424
pitx2 / Q9W5Z2 / paired-like homeodomain 2 / P97474* / Q99697* / paired-like homeodomain transcription factor 2*ENSDARG0000003619420
Q8JI10 / dmbx1a / diencephalon/mesencephalon homeobox 1a / DMBX1* / Q91ZK4* / Q8NFW5* / diencephalon/mesencephalon homeobox 1* / Diencephalon/mesencephalon homeobox protein 1 *ENSDARG0000000992219
prrx1b / paired related homeobox 1b / PRRX1* / P63013* / P54821* / paired related homeobox 1* / Paired mesoderm homeobox protein 1 *ENSDARG0000004202719
otx2b / Q91981 / orthodenticle homeobox 2b / OTX2* / P32243* / orthodenticle homeobox 2*ENSDARG0000001123519
dmbx1b / Q566X8 / diencephalon/mesencephalon homeobox 1b / DMBX1* / Q8NFW5* / diencephalon/mesencephalon homeobox 1*ENSDARG0000000251019
otx1 / Q91994 / orthodenticle homeobox 1 / P32242* / P80205* / Homeobox protein OTX1 *ENSDARG0000009499219
prrx1a / paired related homeobox 1a / PRRX1* / P63013* / P54821* / paired related homeobox 1* / Paired mesoderm homeobox protein 1 *ENSDARG0000003397119
zgc:101100ENSDARG0000002195918
otx2a / Q90267 / orthodenticle homeobox 2aENSDARG0000003070318
pitx3 / Q6QU75 / paired-like homeodomain 3ENSDARG0000007006918
pitx1 / paired-like homeodomain 1 / PITX3* / P78337* / O75364* / paired like homeodomain 3*ENSDARG0000011660818
otx5 / orthodenticle homolog 5ENSDARG0000004348318
crx / cone-rod homeoboxENSDARG0000001198918
mixl1 / Mix paired-like homeobox / Q9H2W2* / Q9WUI0* / Homeobox protein MIXL1 *ENSDARG0000006925214


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary aplastic , abnormal
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 ZFA:0000051 otic vesicle otic vesicle ventro-medial region mislocalised , abnormal
otic vesicle ventro-medial region increased distribution , abnormal
otic vesicle epithelial to mesenchymal transition decreased occurrence , abnormal
otic vesicle neuroblast delamination decreased occurrence , abnormal
otic vesicle ventral region increased amount , abnormal
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 ZFA:0000107 eye eye fused with eye , abnormal
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 ZFA:0000109 forebrain forebrain aplastic , abnormal
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 ZFA:0000128 midbrain midbrain aplastic , abnormal
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 ZFA:0000588 statoacoustic (VIII) ganglion statoacoustic (VIII) ganglion has fewer parts of type statoacoustic (VIII) ganglion neuroblast, abnormal
statoacoustic (VIII) ganglion has fewer parts of type statoacoustic (VIII) ganglion neuron, abnormal
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 ZFA:0001114 head head truncated , abnormal
head hypoplastic , abnormal
head aplastic , abnormal
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 ZFA:0007068 otic epithelium otic epithelium basal part of cell decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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