ENSDARG00000012519


Danio rerio

Features
Gene ID: ENSDARG00000012519
  
Biological name :hcfc1b
  
Synonyms : hcfc1b / host cell factor C1b
  
Possible biological names infered from orthology : HCFC1 / Host cell factor 1 HCF N-terminal chain 1 HCF N-terminal chain 2 HCF N-terminal chain 3 HCF N-terminal chain 4 HCF N-terminal chain 5 HCF N-terminal chain 6 HCF C-terminal chain 1 HCF C-terminal chain 2 HCF C-terminal chain 3 HCF C-terminal chain 4 HCF C-terminal chain 5 HCF C-terminal chain 6 / host cell factor C1 / P51610 / Q61191
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 7506827
Gene end: 7567815
  
Corresponding Affymetrix probe sets: Dr.13068.1.S1_at (Zebrafish Array)   Dr.25613.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000121690
NCBI entrez gene - 565206     See in Manteia.
RefSeq - XM_005166699
RefSeq - XM_021478282
RefSeq - NM_001128537
RefSeq Peptide - NP_001122009
swissprot - A8WIP5
ZFIN ID - ZDB-GENE-030131-2411
Ensembl - ENSDARG00000012519
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HCFC1ENSG00000172534Homo sapiens
 Hcfc1ENSMUSG00000031386Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hcfc1a / host cell factor C1a / HCFC1* / Q61191* / P51610* / host cell factor C1* / Host cell factor 1 HCF N-terminal chain 1 HCF N-terminal chain 2 HCF N-terminal chain 3 HCF N-terminal ch...ENSDARG0000001599072
hcfc2 / host cell factor C2 / Q9Y5Z7*ENSDARG0000005812718
lztr1 / leucine-zipper-like transcription regulator 1 / Q8N653* / Q9CQ33* / Mus musculus leucine-zipper-like transcriptional regulator, 1 (Lztr1), transcript variant 2, mRNA.*ENSDARG000000159056
zmp:0000001301ENSDARG000000908865
Q6GQN7 / rabepk / Rab9 effector protein with kelch motifs / Q7Z6M1*ENSDARG000001121654
krcp / kelch repeat-containing proteinENSDARG000000402244
klhdc10 / kelch domain containing 10 / Q6PAR0* / Q6PID8* / Kelch domain-containing protein 10 *ENSDARG000000077643
zgc:163014ENSDARG000000741003
klhdc2 / kelch domain containing 2 / Q9Y2U9*ENSDARG000001048642
klhdc3 / kelch domain containing 3 / Q9BQ90*ENSDARG000001027722


Protein motifs (from Interpro)
Interpro ID Name
 IPR003961  Fibronectin type III
 IPR006652  Kelch repeat type 1
 IPR013783  Immunoglobulin-like fold
 IPR015915  Kelch-type beta propeller


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002062 chondrocyte differentiation IMP
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 cellular_componentGO:0048188 Set1C/COMPASS complex IEA
 cellular_componentGO:0071339 MLL1 complex IEA


Pathways (from Reactome)
Pathway description
HATs acetylate histones
UCH proteinases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0009019 neuronal stem cell neuronal stem cell cell proliferation disrupted , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000036956 asxl1 / additional sex combs like transcriptional regulator 1 / P59598* / Q8IXJ9* / Putative Polycomb group protein ASXL1 * / additional sex combs like 1, transcriptional regulator*  / complex
 ENSDARG00000063051 bap1 / BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) / Q92560* / Q99PU7* / BRCA1 associated protein 1* / Ubiquitin carboxyl-terminal hydrolase BAP1 *  / complex / reaction
 ENSDARG00000076501 asxl2 / additional sex combs like transcriptional regulator 2 / Q76L83* / putative Polycomb group protein ASXL2 isoform 1 * / additional sex combs like 2, transcriptional regulator*  / complex
 ENSDARG00000030583 foxk2 / forkhead box K2 / Q01167*  / complex
 ENSDARG00000027978 yy1b / YY1 transcription factor b / YY1* / ZFP42* / Q96MM3* / P25490* / Q00899* / zinc finger protein 42* / YY1 transcription factor* / ZFP42 zinc finger protein*  / complex
 ENSDARG00000042796 yy1a / YY1 transcription factor a / YY1* / ZFP42* / Q96MM3* / P25490* / Q00899* / zinc finger protein 42* / YY1 transcription factor* / ZFP42 zinc finger protein*  / complex
 ENSDARG00000011609 si:ch211-262e15.1 / FOXK2* / Q01167* / Q3UCQ1* / forkhead box K2* / Forkhead box protein K2 *  / complex
 ENSDARG00000037872 foxk1 / forkhead box K1 / P42128* / P85037* / Forkhead box protein K1 *  / complex






 

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