ENSDARG00000042796


Danio rerio

Features
Gene ID: ENSDARG00000042796
  
Biological name :yy1a
  
Synonyms : yy1a / YY1 transcription factor a
  
Possible biological names infered from orthology : P25490 / Q00899 / Q96MM3 / YY1 / YY1 transcription factor / ZFP42 / ZFP42 zinc finger protein / zinc finger protein 42
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 30857008
Gene end: 30863252
  
Corresponding Affymetrix probe sets: Dr.812.1.A1_at (Zebrafish Array)   NM_212617_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000062810
NCBI entrez gene - 322397     See in Manteia.
RefSeq - NM_212617
RefSeq Peptide - NP_997782
swissprot - Q7T1S3
ZFIN ID - ZDB-GENE-030131-1117
Ensembl - ENSDARG00000042796
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 YY2ENSGALG00000017388Gallus gallus
 YY1ENSG00000100811Homo sapiens
 ZFP42ENSG00000179059Homo sapiens
 Yy1ENSMUSG00000021264Mus musculus
 Zfp42ENSMUSG00000051176Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
yy1b / YY1 transcription factor b / YY1* / ZFP42* / Q96MM3* / P25490* / Q00899* / zinc finger protein 42* / YY1 transcription factor* / ZFP42 zinc finger protein*ENSDARG0000002797882
znf143a / zinc finger protein 143a / P52747* / Zfp143* / ZNF143* / O70230* / zinc finger protein 143*ENSDARG0000001288720
Q1LYE3 / znf143b / zinc finger protein 143b / P52747* / Zfp143* / ZNF143* / O70230* / zinc finger protein 143*ENSDARG0000004158119
znf76 / zinc finger protein 76 / Zfp523* / P36508* / Q8BMU0* / zinc finger protein 523*ENSDARG0000001327917
ZXDC / si:dkey-156n14.3 / Q2QGD7* / ZXD family zinc finger C*ENSDARG0000005235117
mtf1 / metal-regulatory transcription factor 1 / Q14872*ENSDARG0000010289817
gtf3aa / general transcription factor IIIAa / GTF3A* / Q92664* / transcription factor IIIA * / general transcription factor IIIA*ENSDARG0000003026716
znf410 / zinc finger protein 410 / Q86VK4* / Q8BKX7* / Zfp410*ENSDARG0000000821813
gtf3ab / general transcription factor IIIA, b / GTF3A* / Q92664* / transcription factor IIIA * / general transcription factor IIIA*ENSDARG0000007158313
si:dkey-208k4.2ENSDARG0000010417012


Protein motifs (from Interpro)
Interpro ID Name
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IMP
 biological_processGO:0007420 brain development IMP
 biological_processGO:0007507 heart development IMP
 biological_processGO:0010628 positive regulation of gene expression IMP
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
UCH proteinases
DNA Damage Recognition in GG-NER


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain morphology , abnormal
brain decreased distribution , abnormal
brain decreased size , abnormal
Show

 ZFA:0000029 hindbrain hindbrain decreased size , abnormal
Show

 ZFA:0000107 eye eye decreased distribution , abnormal
Show

 ZFA:0000109 forebrain forebrain decreased size , abnormal
Show

 ZFA:0000114 heart heart morphology , abnormal
heart spatial pattern , abnormal
heart increased length , abnormal
heart hypoplastic , abnormal
heart tubular , abnormal
Show

 ZFA:0000128 midbrain midbrain decreased size , abnormal
Show

 ZFA:0000155 somite somite decreased distribution , abnormal
somite apoptotic , abnormal
Show

 ZFA:0000471 atrium atrium absent , abnormal
atrium aplastic , abnormal
Show

 ZFA:0001094 whole organism whole organism spatial pattern , abnormal
whole organism decreased distribution , abnormal
whole organism increased amount , abnormal
whole organism apoptotic , abnormal
whole organism apoptotic process increased occurrence , abnormal
whole organism anterior-posterior axis decreased length , abnormal
Show

 ZFA:0001115 trunk trunk intersegmental vessel branchiness , abnormal
trunk intersegmental vessel increased branchiness , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel immature , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000015990 hcfc1a / host cell factor C1a / HCFC1* / Q61191* / P51610* / host cell factor C1* / Host cell factor 1 HCF N-terminal chain 1 HCF N-terminal chain 2 HCF N-terminal chain 3 HCF N-terminal ch...  / complex
 ENSDARG00000011609 si:ch211-262e15.1 / FOXK2* / Q01167* / Q3UCQ1* / forkhead box K2* / Forkhead box protein K2 *  / complex
 ENSDARG00000036956 asxl1 / additional sex combs like transcriptional regulator 1 / P59598* / Q8IXJ9* / Putative Polycomb group protein ASXL1 * / additional sex combs like 1, transcriptional regulator*  / complex
 ENSDARG00000015427 hdac1 / histone deacetylase 1 / O09106* / Q13547* / Gm10093*  / complex
 ENSDARG00000030583 foxk2 / forkhead box K2 / Q01167*  / complex
 ENSDARG00000037872 foxk1 / forkhead box K1 / P42128* / P85037* / Forkhead box protein K1 *  / complex
 ENSDARG00000063051 bap1 / BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) / Q92560* / Q99PU7* / BRCA1 associated protein 1* / Ubiquitin carboxyl-terminal hydrolase BAP1 *  / reaction / complex
 ENSDARG00000068436 Q6PI20 / h3f3b.1 / H3 histone, family 3B.1 / H3F3B* / H3F3C* / P84243* / Q6NXT2* / H3 histone family member 3C* / H3 histone family member 3B*  / complex
 ENSDARG00000076501 asxl2 / additional sex combs like transcriptional regulator 2 / Q76L83* / putative Polycomb group protein ASXL2 isoform 1 * / additional sex combs like 2, transcriptional regulator*  / complex
 ENSDARG00000012519 hcfc1b / host cell factor C1b / HCFC1* / Q61191* / P51610* / host cell factor C1* / Host cell factor 1 HCF N-terminal chain 1 HCF N-terminal chain 2 HCF N-terminal chain 3 HCF N-terminal ch...  / complex
 ENSDARG00000105345 zgc:173552  / complex
 ENSDARG00000105359 Q4QRF4 / FP325123.1 / Histone H3.2   / complex






 

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