ENSDARG00000021110


Danio rerio

Features
Gene ID: ENSDARG00000021110
  
Biological name :poc1b
  
Synonyms : A2CEH0 / poc1b / POC1 centriolar protein B
  
Possible biological names infered from orthology : Q8BHD1 / Q8TC44
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 18366978
Gene end: 18435481
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000026057
NCBI entrez gene - 386932     See in Manteia.
RefSeq - NM_200118
RefSeq - XM_009297892
RefSeq Peptide - NP_956412
swissprot - A2CEH0
ZFIN ID - ZDB-GENE-031118-54
Ensembl - ENSDARG00000021110
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 POC1BENSGALG00000035493Gallus gallus
 POC1BENSG00000139323Homo sapiens
 Poc1bENSMUSG00000019952Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
katnb1 / Q7ZUV2 / katanin p80 (WD repeat containing) subunit B 1 / Q9BVA0* / Q8BG40* / katanin regulatory subunit B1* / Katanin p80 WD40 repeat-containing subunit B1 *ENSDARG0000000545621
poc1a / POC1 centriolar protein A / Q8JZX3* / Q8NBT0*ENSDARG0000007853321
pafah1b1b / platelet-activating factor acetylhydrolase 1b, regulatory subunit 1b / P43034* / PAFAH1B1* / platelet activating factor acetylhydrolase 1b regulatory subunit 1*ENSDARG0000002659518
Q7T394 / pafah1b1a / platelet-activating factor acetylhydrolase 1b, regulatory subunit 1a / P43034* / P63005* / PAFAH1B1* / platelet-activating factor acetylhydrolase, isoform 1b, subunit 1...ENSDARG0000003201318
nle1 / notchless homolog 1 (Drosophila) / Q8VEJ4* / Q9NVX2* / notchless homolog 1* / Notchless protein homolog 1 *ENSDARG0000005710518
wdr5 / WD repeat domain 5 / WDR5B* / Q9D7H2* / P61964* / P61965* / Q86VZ2* / WD repeat domain 5B*ENSDARG0000001690318
snrnp40 / small nuclear ribonucleoprotein 40 (U5) / Q96DI7* / Q6PE01* / small nuclear ribonucleoprotein U5 subunit 40* / U5 small nuclear ribonucleoprotein 40 kDa protein *ENSDARG0000002316017
daw1 / dynein assembly factor with WDR repeat domains 1 / Q8N136* / dynein assembly factor with WD repeats 1*ENSDARG0000002146215
wdr38 / WD repeat domain 38 / Q5JTN6*ENSDARG0000004480111
wdr61 / WD repeat domain 61 / Q9ERF3* / Q9GZS3*ENSDARG0000000775511


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR020472  G-protein beta WD-40 repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001895 retina homeostasis ISS
 biological_processGO:0003014 renal system process IMP
 biological_processGO:0007507 heart development IMP
 biological_processGO:0007634 optokinetic behavior IMP
 biological_processGO:0010842 retina layer formation IMP
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0060271 cilium assembly ISS
 biological_processGO:0060287 epithelial cilium movement involved in determination of left/right asymmetry IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005814 centriole IEA
 cellular_componentGO:0005856 cytoskeleton IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle cilium decreased length , abnormal
Kupffers vesicle motile cilium shortened , abnormal
Show

 ZFA:0000008 brain brain decreased size , abnormal
Show

 ZFA:0000009 cardiac ventricle cardiac ventricle dilated , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000076 swim bladder swim bladder uninflated , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
eye movement quality , abnormal
Show

 ZFA:0000114 heart heart edematous , abnormal
heart mislocalised laterally , abnormal
heart morphology , abnormal
Show

 ZFA:0000119 retinal inner nuclear layer retinal inner nuclear layer cell death increased occurrence , abnormal
Show

 ZFA:0000150 pronephric duct pronephric duct cilium disorganized , abnormal
Show

 ZFA:0000151 pronephros pronephros cystic , abnormal
Show

 ZFA:0000152 retina retina neuron disorganized , abnormal
retina photoreceptor connecting cilium decreased length , abnormal
retina photoreceptor connecting cilium decreased amount , abnormal
retina cell death increased occurrence , abnormal
Show

 ZFA:0000529 kidney kidney cystic , abnormal
Show

 ZFA:0001094 whole organism whole organism curved , abnormal
whole organism decreased length , abnormal
whole organism shortened , abnormal
whole organism decreased size , abnormal
whole organism viability , abnormal
whole organism anterior-posterior axis decreased length , abnormal
whole organism anterior-posterior axis curved ventral , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved , abnormal
Show

 ZFA:0001272 palatoquadrate arch palatoquadrate arch decreased length , abnormal
palatoquadrate arch malformed , abnormal
Show

 ZFA:0001273 ventral mandibular arch ventral mandibular arch decreased length , abnormal
ventral mandibular arch malformed , abnormal
Show

 ZFA:0001306 pharyngeal arch pharyngeal arch aplastic , abnormal
Show

 ZFA:0001466 photoreceptor outer segment layer photoreceptor outer segment layer disorganized , abnormal
photoreceptor outer segment layer shortened , abnormal
Show

 ZFA:0007037 posterior neural tube posterior neural tube cilium disorganized , abnormal
posterior neural tube cilium distended , abnormal
Show

 ZFA:0009090 pigment cell pigment cell mislocalised , abnormal
Show

 ZFA:0009091 melanocyte melanocyte mislocalised , abnormal
melanocyte spatial pattern , abnormal
Show

 ZFA:0009127 photoreceptor cell photoreceptor cell photoreceptor outer segment aplastic/hypoplastic , abnormal
Show

 ZFA:0009262 retinal cone cell retinal cone cell decreased length , abnormal
retinal cone cell photoreceptor outer segment aplastic/hypoplastic , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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