ENSDARG00000029072


Danio rerio

Features
Gene ID: ENSDARG00000029072
  
Biological name :klf6a
  
Synonyms : klf6a / Kruppel-like factor 6a
  
Possible biological names infered from orthology : KLF6 / Kruppel like factor 6 / Q99612
  
Species: Danio rerio
  
Chr. number: 24
Strand: -1
Band:
Gene start: 4141484
Gene end: 4148915
  
Corresponding Affymetrix probe sets: Dr.20339.1.S1_at (Zebrafish Array)   NM_201461_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000037789
Ensembl peptide - ENSDARP00000114929
NCBI entrez gene - 280650     See in Manteia.
RefSeq - NM_201461
RefSeq Peptide - NP_958869
swissprot - F1R7F0
swissprot - E9QDL1
ZFIN ID - ZDB-GENE-021115-9
Ensembl - ENSDARG00000029072
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KLF6ENSGALG00000033178Gallus gallus
 KLF6ENSG00000067082Homo sapiens
 Klf6ENSMUSG00000000078Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
klf7b / Kruppel-like factor 7b / KLF7* / Q99JB0* / O75840* / Kruppel like factor 7* / Krueppel-like factor 7 *ENSDARG0000004382152
klf7a / Kruppel-like factor 7a / KLF7* / Q99JB0* / O75840* / Kruppel like factor 7* / Krueppel-like factor 7 *ENSDARG0000007385752
klf6b / Kruppel-like factor 6bENSDARG0000003856148
klf5l / Kruppel-like factor 5 likeENSDARG0000001875740
klf5a / pibf1 / Kruppel-like factor 5a / KLF5* / Q9Z0Z7* / Q13887* / Kruppel like factor 5* / Krueppel-like factor 5 *ENSDARG0000001550636
klf2a / Kruppel-like factor 2a / KLF1* / KLF2* / Q9Y5W3* / Q13351* / Q60843* / Kruppel like factor 2* / Kruppel like factor 1* / Krueppel-like factor 2 *ENSDARG0000004266734
klf5b / Kruppel-like factor 5b / KLF5* / Q9Z0Z7* / Q13887* / Kruppel like factor 5* / Krueppel-like factor 5 *ENSDARG0000006210633
klf12b / Kruppel-like factor 12b / KLF12* / Q9Y4X4* / O35738* / Kruppel like factor 12* / Krueppel-like factor 12 *ENSDARG0000003219732
klf2b / Kruppel-like factor 2b / KLF1* / KLF2* / Q9Y5W3* / Q13351* / Kruppel like factor 1* / Kruppel like factor 2*ENSDARG0000004043232
klf8 / Kruppel-like factor 8 / O95600* / Q8BLM0* / Krueppel-like factor 8 *ENSDARG0000006066132
klf17 / Kruppel-like factor 17ENSDARG0000003879231
klf12a / Kruppel-like factor 12aENSDARG0000001531231
klf1 / Kruppel-like factor 1 (erythroid)ENSDARG0000001740031
klf15 / Kruppel-like factor 15 / Q9EPW2* / Q9UIH9* / Krueppel-like factor 15 *ENSDARG0000009112730
klf3 / Kruppel-like factor 3 (basic) / P57682* / Q60980* / Kruppel like factor 3* / Krueppel-like factor 3 *ENSDARG0000001549529
si:ch211-117k10.3ENSDARG0000009091426
klf4 / Kruppel-like factor 4 / O43474*ENSDARG0000007992214


Protein motifs (from Interpro)
Interpro ID Name
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001889 liver development IMP
 biological_processGO:0021634 optic nerve formation IDA
 biological_processGO:0031016 pancreas development IMP
 biological_processGO:0035265 organ growth IMP
 biological_processGO:0043249 erythrocyte maturation IMP
 biological_processGO:0048565 digestive tract development IMP
 molecular_functionGO:0001158 enhancer sequence-specific DNA binding IDA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003682 chromatin binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000033 intermediate cell mass of mesoderm intermediate cell mass of mesoderm posterior region decreased amount , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000084 yolk yolk edematous , abnormal
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 ZFA:0000094 blood island blood island cell cycle process quality , abnormal
blood island cell proliferation decreased process quality , abnormal
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 ZFA:0000099 brain vasculature brain vasculature hemorrhagic , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000112 gut gut decreased size , abnormal
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 ZFA:0000123 liver liver decreased size , abnormal
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 ZFA:0001094 whole organism whole organism decreased size , abnormal
whole organism posterior region decreased amount , abnormal
whole organism decreased amount , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
head edematous , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton decreased size , abnormal
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 ZFA:0001249 exocrine pancreas exocrine pancreas decreased size , abnormal
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 ZFA:0001286 caudal vein plexus caudal vein plexus decreased thickness , abnormal
caudal vein plexus decreased volume , abnormal
caudal vein plexus disorganized , abnormal
caudal vein plexus hematopoietic stem cell decreased amount , abnormal
Show

 ZFA:0001338 intestine intestine decreased size , abnormal
Show

 ZFA:0005125 intestinal villus intestinal villus absent , abnormal
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 ZFA:0005898 caudal hematopoietic tissue caudal hematopoietic tissue hematopoietic stem cell proliferation decreased occurrence , abnormal
caudal hematopoietic tissue hematopoietic stem cell decreased amount , abnormal
caudal hematopoietic tissue hematopoietic multipotent progenitor cell decreased amount , abnormal
Show

 ZFA:0009014 hematopoietic stem cell hematopoietic stem cell decreased distribution , abnormal
hematopoietic stem cell decreased amount , abnormal
Show

 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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