ENSDARG00000060661


Danio rerio

Features
Gene ID: ENSDARG00000060661
  
Biological name :klf8
  
Synonyms : klf8 / Kruppel-like factor 8
  
Possible biological names infered from orthology : Krueppel-like factor 8 / O95600 / Q8BLM0
  
Species: Danio rerio
  
Chr. number: 21
Strand: 1
Band:
Gene start: 38033226
Gene end: 38111218
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000123206
Ensembl peptide - ENSDARP00000156773
Ensembl peptide - ENSDARP00000080163
Ensembl peptide - ENSDARP00000114581
NCBI entrez gene - 562805     See in Manteia.
swissprot - A0S0R1
swissprot - F1QE03
swissprot - F1QE84
ZFIN ID - ZDB-GENE-070424-152
Ensembl - ENSDARG00000060661
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000044078Gallus gallus
 KLF8ENSG00000102349Homo sapiens
 Klf8ENSMUSG00000041649Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
klf12b / Kruppel-like factor 12b / KLF12* / Q9Y4X4* / O35738* / Kruppel like factor 12* / Krueppel-like factor 12 *ENSDARG0000003219744
klf12a / Kruppel-like factor 12aENSDARG0000001531238
klf3 / Kruppel-like factor 3 (basic) / P57682* / Q60980* / Kruppel like factor 3* / Krueppel-like factor 3 *ENSDARG0000001549533
klf5a / pibf1 / Kruppel-like factor 5a / KLF5* / Q9Z0Z7* / Q13887* / Kruppel like factor 5* / Krueppel-like factor 5 *ENSDARG0000001550629
klf5l / Kruppel-like factor 5 likeENSDARG0000001875728
klf6a / Kruppel-like factor 6a / KLF6* / Q99612* / Kruppel like factor 6*ENSDARG0000002907226
klf7a / Kruppel-like factor 7a / KLF7* / Q99JB0* / O75840* / Kruppel like factor 7* / Krueppel-like factor 7 *ENSDARG0000007385726
klf5b / Kruppel-like factor 5b / KLF5* / Q9Z0Z7* / Q13887* / Kruppel like factor 5* / Krueppel-like factor 5 *ENSDARG0000006210626
klf7b / Kruppel-like factor 7b / KLF7* / Q99JB0* / O75840* / Kruppel like factor 7* / Krueppel-like factor 7 *ENSDARG0000004382126
klf1 / Kruppel-like factor 1 (erythroid)ENSDARG0000001740025
klf2a / Kruppel-like factor 2a / KLF1* / KLF2* / Q9Y5W3* / Q13351* / Q60843* / Kruppel like factor 2* / Kruppel like factor 1* / Krueppel-like factor 2 *ENSDARG0000004266724
klf2b / Kruppel-like factor 2b / KLF1* / KLF2* / Q9Y5W3* / Q13351* / Kruppel like factor 1* / Kruppel like factor 2*ENSDARG0000004043224
klf17 / Kruppel-like factor 17ENSDARG0000003879222
si:ch211-117k10.3ENSDARG0000009091422
klf6b / Kruppel-like factor 6bENSDARG0000003856122
klf15 / Kruppel-like factor 15 / Q9EPW2* / Q9UIH9* / Krueppel-like factor 15 *ENSDARG0000009112721
klf4 / Kruppel-like factor 4 / O43474*ENSDARG0000007992211


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0021549 cerebellum development IMP
 biological_processGO:0021702 cerebellar Purkinje cell differentiation IMP
 biological_processGO:0021707 cerebellar granule cell differentiation IMP
 molecular_functionGO:0003676 nucleic acid binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle cilium decreased length , abnormal
Kupffers vesicle cilium decreased amount , abnormal
Show

 ZFA:0000100 cerebellum cerebellum morphology , abnormal
cerebellum apoptotic process increased occurrence , abnormal
cerebellum cell proliferation in hindbrain decreased occurrence , abnormal
Show

 ZFA:0000101 diencephalon diencephalon in_left_side_of absent , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000114 heart heart morphology , abnormal
Show

 ZFA:0000115 heart rudiment heart rudiment absent , abnormal
Show

 ZFA:0000121 lateral plate mesoderm lateral plate mesoderm left side absent , abnormal
lateral plate mesoderm absent , abnormal
lateral plate mesoderm decreased amount , abnormal
lateral plate mesoderm left side decreased amount , abnormal
Show

 ZFA:0000123 liver liver bilateral , abnormal
liver mislocalised , abnormal
liver aplastic , abnormal
Show

 ZFA:0000140 pancreas pancreas bilateral , abnormal
pancreas mislocalised , abnormal
pancreas aplastic , abnormal
Show

 ZFA:0000360 heart tube heart tube displaced to whole organism right side, abnormal
heart tube medial orientation , abnormal
Show

 ZFA:0001094 whole organism whole organism has fewer parts of type forerunner cell group , abnormal
Show

 ZFA:0001691 cerebellar granule cell cerebellar granule cell decreased amount , abnormal
Show

 ZFA:0005041 anterior lateral plate mesoderm anterior lateral plate mesoderm absent , abnormal
Show

 ZFA:0005042 posterior lateral plate mesoderm posterior lateral plate mesoderm decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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