ENSG00000102349


Homo sapiens

Features
Gene ID: ENSG00000102349
  
Biological name :KLF8
  
Synonyms : KLF8 / Kruppel like factor 8 / O95600
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: p11.21
Gene start: 56232421
Gene end: 56287889
  
Corresponding Affymetrix probe sets: 219930_at (Human Genome U133 Plus 2.0 Array)   230986_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000364063
Ensembl peptide - ENSP00000417303
Ensembl peptide - ENSP00000431911
Ensembl peptide - ENSP00000492126
NCBI entrez gene - 11279     See in Manteia.
OMIM - 300286
RefSeq - NM_001324105
RefSeq - NM_007250
RefSeq - XM_017029250
RefSeq - NM_001159296
RefSeq - NM_001324099
RefSeq - NM_001324100
RefSeq - NM_001324102
RefSeq - NM_001324104
RefSeq - XM_005261977
RefSeq - XM_005261979
RefSeq - XM_006724575
RefSeq - XM_006724576
RefSeq - XM_011530759
RefSeq Peptide - NP_001311033
RefSeq Peptide - NP_009181
RefSeq Peptide - NP_001311029
RefSeq Peptide - NP_001311031
RefSeq Peptide - NP_001311034
RefSeq Peptide - NP_001152768
RefSeq Peptide - NP_001311028
swissprot - O95600
swissprot - Q05BZ3
swissprot - A0A024R9X4
Ensembl - ENSG00000102349
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 klf8ENSDARG00000060661Danio rerio
 ENSGALG00000044078Gallus gallus
 Klf8ENSMUSG00000041649Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KLF12 / Q9Y4X4 / Kruppel like factor 12ENSG0000011892247
KLF3 / P57682 / Kruppel like factor 3ENSG0000010978735
KLF5 / Q13887 / Kruppel like factor 5ENSG0000010255430
KLF4 / O43474 / Kruppel like factor 4ENSG0000013682628
KLF6 / Q99612 / Kruppel like factor 6ENSG0000006708226
KLF1 / Q13351 / Kruppel like factor 1ENSG0000010561026
KLF7 / O75840 / Kruppel like factor 7ENSG0000011826326
KLF15 / Q9UIH9 / Kruppel like factor 15ENSG0000016388425
KLF2 / Q9Y5W3 / Kruppel like factor 2ENSG0000012752824
KLF18 / Kruppel like factor 18ENSG0000028303920
KLF17 / Q5JT82 / Kruppel like factor 17ENSG0000017187219


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016235 aggresome IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IMP
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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