ENSG00000102554


Homo sapiens

Features
Gene ID: ENSG00000102554
  
Biological name :KLF5
  
Synonyms : KLF5 / Kruppel like factor 5 / Q13887
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: 1
Band: q22.1
Gene start: 73054976
Gene end: 73077542
  
Corresponding Affymetrix probe sets: 209211_at (Human Genome U133 Plus 2.0 Array)   209212_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000366915
Ensembl peptide - ENSP00000440407
NCBI entrez gene - 688     See in Manteia.
OMIM - 602903
RefSeq - NM_001730
RefSeq - NM_001286818
RefSeq Peptide - NP_001273747
RefSeq Peptide - NP_001721
swissprot - Q13887
swissprot - Q5T6X2
Ensembl - ENSG00000102554
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 klf5aENSDARG00000015506Danio rerio
 klf5bENSDARG00000062106Danio rerio
 ENSGALG00000016927Gallus gallus
 Klf5ENSMUSG00000005148Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KLF6 / Q99612 / Kruppel like factor 6ENSG0000006708225
KLF4 / O43474 / Kruppel like factor 4ENSG0000013682624
KLF8 / O95600 / Kruppel like factor 8ENSG0000010234924
KLF1 / Q13351 / Kruppel like factor 1ENSG0000010561024
KLF7 / O75840 / Kruppel like factor 7ENSG0000011826324
KLF2 / Q9Y5W3 / Kruppel like factor 2ENSG0000012752823
KLF3 / P57682 / Kruppel like factor 3ENSG0000010978723
KLF12 / Q9Y4X4 / Kruppel like factor 12ENSG0000011892223
KLF15 / Q9UIH9 / Kruppel like factor 15ENSG0000016388422
KLF17 / Q5JT82 / Kruppel like factor 17ENSG0000017187219
KLF18 / Kruppel like factor 18ENSG0000028303917


Protein motifs (from Interpro)
Interpro ID Name
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR030401  Krueppel-like factor 5
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0030033 microvillus assembly IEA
 biological_processGO:0032534 regulation of microvillus assembly IEA
 biological_processGO:0035914 skeletal muscle cell differentiation IEA
 biological_processGO:0045600 positive regulation of fat cell differentiation IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0060576 intestinal epithelial cell development IEA
 biological_processGO:0071407 cellular response to organic cyclic compound IEA
 biological_processGO:1901653 cellular response to peptide IEA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Transcriptional regulation of white adipocyte differentiation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr