ENSG00000118922


Homo sapiens

Features
Gene ID: ENSG00000118922
  
Biological name :KLF12
  
Synonyms : KLF12 / Kruppel like factor 12 / Q9Y4X4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: -1
Band: q22.1
Gene start: 73686089
Gene end: 73995056
  
Corresponding Affymetrix probe sets: 206965_at (Human Genome U133 Plus 2.0 Array)   206966_s_at (Human Genome U133 Plus 2.0 Array)   208467_at (Human Genome U133 Plus 2.0 Array)   214276_at (Human Genome U133 Plus 2.0 Array)   227261_at (Human Genome U133 Plus 2.0 Array)   229881_at (Human Genome U133 Plus 2.0 Array)   238940_at (Human Genome U133 Plus 2.0 Array)   239019_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000366897
NCBI entrez gene - 11278     See in Manteia.
OMIM - 607531
RefSeq - XM_017020385
RefSeq - NM_007249
RefSeq - XM_011534912
RefSeq - XM_017020384
RefSeq - XM_005266251
RefSeq - XM_011534907
RefSeq - XM_011534908
RefSeq - XM_011534909
RefSeq - XM_011534910
RefSeq - XM_011534911
RefSeq Peptide - NP_009180
swissprot - Q9Y4X4
Ensembl - ENSG00000118922
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 klf12bENSDARG00000032197Danio rerio
 KLF12ENSGALG00000016926Gallus gallus
 Klf12ENSMUSG00000072294Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KLF8 / O95600 / Kruppel like factor 8ENSG0000010234942
KLF3 / P57682 / Kruppel like factor 3ENSG0000010978738
KLF5 / Q13887 / Kruppel like factor 5ENSG0000010255426
KLF4 / O43474 / Kruppel like factor 4ENSG0000013682625
KLF1 / Q13351 / Kruppel like factor 1ENSG0000010561025
KLF7 / O75840 / Kruppel like factor 7ENSG0000011826325
KLF6 / Q99612 / Kruppel like factor 6ENSG0000006708225
KLF2 / Q9Y5W3 / Kruppel like factor 2ENSG0000012752823
KLF18 / Kruppel like factor 18ENSG0000028303920
KLF15 / Q9UIH9 / Kruppel like factor 15ENSG0000016388419
KLF17 / Q5JT82 / Kruppel like factor 17ENSG0000017187218


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0003714 transcription corepressor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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