ENSG00000109787


Homo sapiens

Features
Gene ID: ENSG00000109787
  
Biological name :KLF3
  
Synonyms : KLF3 / Kruppel like factor 3 / P57682
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: p14
Gene start: 38664196
Gene end: 38701042
  
Corresponding Affymetrix probe sets: 219657_s_at (Human Genome U133 Plus 2.0 Array)   222913_at (Human Genome U133 Plus 2.0 Array)   225133_at (Human Genome U133 Plus 2.0 Array)   225140_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000261438
Ensembl peptide - ENSP00000421252
NCBI entrez gene - 51274     See in Manteia.
OMIM - 609392
RefSeq - NM_016531
RefSeq - XM_017008279
RefSeq Peptide - NP_057615
swissprot - A0A024R9T8
swissprot - P57682
Ensembl - ENSG00000109787
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 klf3ENSDARG00000015495Danio rerio
 KLF3ENSGALG00000041717Gallus gallus
 Klf3ENSMUSG00000029178Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KLF12 / Q9Y4X4 / Kruppel like factor 12ENSG0000011892245
KLF8 / O95600 / Kruppel like factor 8ENSG0000010234937
KLF5 / Q13887 / Kruppel like factor 5ENSG0000010255430
KLF4 / O43474 / Kruppel like factor 4ENSG0000013682629
KLF6 / Q99612 / Kruppel like factor 6ENSG0000006708227
KLF1 / Q13351 / Kruppel like factor 1ENSG0000010561026
KLF2 / Q9Y5W3 / Kruppel like factor 2ENSG0000012752826
KLF7 / O75840 / Kruppel like factor 7ENSG0000011826324
KLF15 / Q9UIH9 / Kruppel like factor 15ENSG0000016388421
KLF18 / Kruppel like factor 18ENSG0000028303921
KLF17 / Q5JT82 / Kruppel like factor 17ENSG0000017187220


Protein motifs (from Interpro)
Interpro ID Name
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development TAS
 biological_processGO:1901653 cellular response to peptide IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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