ENSG00000118263


Homo sapiens

Features
Gene ID: ENSG00000118263
  
Biological name :KLF7
  
Synonyms : KLF7 / Kruppel like factor 7 / O75840
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q33.3
Gene start: 207074137
Gene end: 207167267
  
Corresponding Affymetrix probe sets: 1555420_a_at (Human Genome U133 Plus 2.0 Array)   204334_at (Human Genome U133 Plus 2.0 Array)   238482_at (Human Genome U133 Plus 2.0 Array)   238517_at (Human Genome U133 Plus 2.0 Array)   240432_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000393268
Ensembl peptide - ENSP00000392015
Ensembl peptide - ENSP00000397245
Ensembl peptide - ENSP00000413590
Ensembl peptide - ENSP00000412950
Ensembl peptide - ENSP00000403284
Ensembl peptide - ENSP00000398572
Ensembl peptide - ENSP00000309570
Ensembl peptide - ENSP00000387510
NCBI entrez gene - 8609     See in Manteia.
OMIM - 604865
RefSeq - XM_017005164
RefSeq - NM_001270943
RefSeq - NM_001270944
RefSeq - NM_003709
RefSeq - XM_005246926
RefSeq - XM_006712815
RefSeq - XM_011512072
RefSeq - XM_011512073
RefSeq - XM_011512074
RefSeq - XM_017005161
RefSeq - XM_017005162
RefSeq - NM_001270942
RefSeq Peptide - NP_001257872
RefSeq Peptide - NP_001257873
RefSeq Peptide - NP_003700
RefSeq Peptide - NP_001257871
swissprot - A0A024R3X8
swissprot - E9PHC9
swissprot - O75840
swissprot - E7EUU0
swissprot - E7EQY2
swissprot - C9JX20
Ensembl - ENSG00000118263
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 klf7aENSDARG00000073857Danio rerio
 klf7bENSDARG00000043821Danio rerio
 KLF7ENSGALG00000008501Gallus gallus
 Klf7ENSMUSG00000025959Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KLF6 / Q99612 / Kruppel like factor 6ENSG0000006708252
KLF5 / Q13887 / Kruppel like factor 5ENSG0000010255437
KLF12 / Q9Y4X4 / Kruppel like factor 12ENSG0000011892233
KLF1 / Q13351 / Kruppel like factor 1ENSG0000010561032
KLF8 / O95600 / Kruppel like factor 8ENSG0000010234931
KLF4 / O43474 / Kruppel like factor 4ENSG0000013682629
KLF2 / Q9Y5W3 / Kruppel like factor 2ENSG0000012752829
KLF3 / P57682 / Kruppel like factor 3ENSG0000010978728
KLF15 / Q9UIH9 / Kruppel like factor 15ENSG0000016388426
KLF18 / Kruppel like factor 18ENSG0000028303922
KLF17 / Q5JT82 / Kruppel like factor 17ENSG0000017187222


Protein motifs (from Interpro)
Interpro ID Name
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II TAS
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007409 axonogenesis IEA
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0048813 dendrite morphogenesis IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0003713 transcription coactivator activity TAS
 molecular_functionGO:0008270 zinc ion binding TAS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr