Danio rerio

Gene ID: ENSDARG00000033099
Biological name :kif7
Synonyms : kif7 / kinesin family member 7
Possible biological names infered from orthology : Q2M1P5
Species: Danio rerio
Chr. number: 7
Strand: -1
Gene start: 14393059
Gene end: 14446512
Corresponding Affymetrix probe sets: Dr.18327.1.S1_at (Zebrafish Array)   
Cross references: Ensembl peptide - ENSDARP00000041576
NCBI entrez gene - 544651     See in Manteia.
swissprot - F1QH25
ZFIN ID - ZDB-GENE-050307-1
Ensembl - ENSDARG00000033099
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KIF7ENSGALG00000006611Gallus gallus
 KIF7ENSG00000166813Homo sapiens
 Kif7ENSMUSG00000050382Mus musculus

Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
kif21b / kinesin family member 21B / O75037*ENSDARG0000000973322
kif21a / kinesin family member 21A / Q7Z4S6* / Q9QXL2* / Kinesin-like protein KIF21A *ENSDARG0000006113121
kif4 / kinesin family member 4 / KIF4A* / KIF4B* / Q2VIQ3* / O95239* / P33174* / kinesin family member 4A* / kinesin family member 4B* / Chromosome-associated kinesin KIF4 *ENSDARG0000000546220
kif5ba / kif5bb / kinesin family member 5B, b / KIF5B* / P33176* / kinesin family member 5B*ENSDARG0000010339418
kif5ba / kinesin family member 5B, a / KIF5B* / Q61768* / P33176* / Kinesin-1 heavy chain * / kinesin family member 5B*ENSDARG0000007413118
kif5c / kinesin family member 5C / O60282* / P28738* / Kinesin heavy chain isoform 5C *ENSDARG0000007602717
kif5ab / kinesin family member 5A, b / KIF5A* / P33175* / Q12840* / kinesin family member 5A* / Kinesin heavy chain isoform 5A *ENSDARG0000005981817
cenpe / centromere protein E / Q02224*ENSDARG0000006338517
kif5aa / kinesin family member 5A, a / KIF5A* / Q12840* / kinesin family member 5A*ENSDARG0000009893617
kif17 / kinesin family member 17 / Q99PW8* / Q9P2E2* / Kinesin-like protein KIF17 *ENSDARG0000005523816
kif3a / kinesin family member 3A / P28741* / Q9Y496* / Kinesin-like protein KIF3A *ENSDARG0000008753815
kif15 / kinesin family member 15 / Q6P9L6* / Q9NS87* / Kinesin-like protein KIF15 *ENSDARG0000001207315
kif3ca / kinesin family member 3Ca / KIF3C* / O14782* / kinesin family member 3C*ENSDARG0000001716215
kif11 / kinesin family member 11 / P52732* / Q6P9P6* / Kinesin-like protein KIF11 *ENSDARG0000001094815
kif3b / kinesin family member 3B / O15066* / Q61771* / Kinesin-like protein KIF3B Kinesin-like protein KIF3B, N-terminally processed*ENSDARG0000010112015
kif3cb / kinesin family member 3Cb / KIF3C* / O14782* / O35066* / kinesin family member 3C* / Kinesin-like protein KIF3C *ENSDARG0000007950014

Protein motifs (from Interpro)
Interpro ID Name
 IPR001752  Kinesin motor domain
 IPR019821  Kinesin motor domain, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase

Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007018 microtubule-based movement IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA

Pathways (from Reactome)
Pathway description
Hedgehog off state
Hedgehog on state

Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000075 spinal cord spinal cord mislocalised , abnormal

 ZFA:0000107 eye eye decreased size , abnormal

 ZFA:0000135 notochord notochord kinked , abnormal

 ZFA:0000143 retinal photoreceptor layer retinal photoreceptor layer photoreceptor outer segment decreased amount , abnormal

 ZFA:0000155 somite somite shape , abnormal
somite increased width , abnormal
somite obtuse angle to somite , abnormal

 ZFA:0001056 myotome myotome muscle pioneer increased amount , abnormal
myotome fast muscle cell increased amount , abnormal
myotome increased distribution , abnormal
myotome decreased distribution , abnormal

 ZFA:0001086 muscle pioneer muscle pioneer increased amount , abnormal
muscle pioneer decreased distribution , abnormal
muscle pioneer decreased amount , abnormal

 ZFA:0001094 whole organism whole organism anterior-posterior axis decreased length , abnormal
whole organism absent , abnormal
whole organism decreased amount , abnormal

 ZFA:0001114 head head decreased size , abnormal

 ZFA:0001466 photoreceptor outer segment layer photoreceptor outer segment layer absent , abnormal
photoreceptor outer segment layer decreased size , abnormal
photoreceptor outer segment layer decreased height , abnormal

 ZFA:0005028 ventral wall of dorsal aorta ventral wall of dorsal aorta hematopoietic stem cell amount , ameliorated

 ZFA:0009116 slow muscle cell slow muscle cell increased amount , abnormal


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match


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