ENSDARG00000010948


Danio rerio

Features
Gene ID: ENSDARG00000010948
  
Biological name :kif11
  
Synonyms : kif11 / kinesin family member 11
  
Possible biological names infered from orthology : Kinesin-like protein KIF11 / P52732 / Q6P9P6
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 19481049
Gene end: 19497006
  
Corresponding Affymetrix probe sets: Dr.1557.1.S1_at (Zebrafish Array)   NM_173261_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000006884
NCBI entrez gene - 195818     See in Manteia.
RefSeq - XM_021467102
RefSeq - XM_021467103
RefSeq - NM_173261
RefSeq Peptide - NP_775368
swissprot - F1QK82
ZFIN ID - ZDB-GENE-020426-1
Ensembl - ENSDARG00000010948
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KIF11ENSGALG00000030597Gallus gallus
 KIF11ENSG00000138160Homo sapiens
 Kif11ENSMUSG00000012443Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
kif3ca / kinesin family member 3Ca / KIF3C* / O14782* / kinesin family member 3C*ENSDARG0000001716221
kif21b / kinesin family member 21B / O75037*ENSDARG0000000973321
kif5ba / kinesin family member 5B, a / KIF5B* / Q61768* / P33176* / Kinesin-1 heavy chain * / kinesin family member 5B*ENSDARG0000007413121
kif3a / kinesin family member 3A / P28741* / Q9Y496* / Kinesin-like protein KIF3A *ENSDARG0000008753821
kif5ba / kif5bb / kinesin family member 5B, b / KIF5B* / P33176* / kinesin family member 5B*ENSDARG0000010339421
kif3b / kinesin family member 3B / O15066* / Q61771* / Kinesin-like protein KIF3B Kinesin-like protein KIF3B, N-terminally processed*ENSDARG0000010112021
kif5c / kinesin family member 5C / O60282* / P28738* / Kinesin heavy chain isoform 5C *ENSDARG0000007602720
kif4 / kinesin family member 4 / KIF4A* / KIF4B* / Q2VIQ3* / O95239* / P33174* / kinesin family member 4A* / kinesin family member 4B* / Chromosome-associated kinesin KIF4 *ENSDARG0000000546220
kif3cb / kinesin family member 3Cb / KIF3C* / O14782* / O35066* / kinesin family member 3C* / Kinesin-like protein KIF3C *ENSDARG0000007950020
kif5aa / kinesin family member 5A, a / KIF5A* / Q12840* / kinesin family member 5A*ENSDARG0000009893620
kif17 / kinesin family member 17 / Q99PW8* / Q9P2E2* / Kinesin-like protein KIF17 *ENSDARG0000005523820
kif21a / kinesin family member 21A / Q7Z4S6* / Q9QXL2* / Kinesin-like protein KIF21A *ENSDARG0000006113120
kif5ab / kinesin family member 5A, b / KIF5A* / P33175* / Q12840* / kinesin family member 5A* / Kinesin heavy chain isoform 5A *ENSDARG0000005981820
kif15 / kinesin family member 15 / Q6P9L6* / Q9NS87* / Kinesin-like protein KIF15 *ENSDARG0000001207320
kif7 / kinesin family member 7 / Q2M1P5*ENSDARG0000003309919
cenpe / centromere protein E / Q02224*ENSDARG0000006338519
CABZ01066312.1ENSDARG000001006242


Protein motifs (from Interpro)
Interpro ID Name
 IPR001752  Kinesin motor domain
 IPR019821  Kinesin motor domain, conserved site
 IPR025901  Kinesin-associated microtubule-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IMP
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0007059 chromosome segregation IBA
 biological_processGO:0022008 neurogenesis IMP
 biological_processGO:0051726 regulation of cell cycle IMP
 biological_processGO:0090307 mitotic spindle assembly IBA
 cellular_componentGO:0005871 kinesin complex IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0008574 ATP-dependent microtubule motor activity, plus-end-directed IBA


Pathways (from Reactome)
Pathway description
Kinesins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain necrotic , abnormal
Show

 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000075 spinal cord spinal cord has extra parts of type ventricular zone radial glial cell, abnormal
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 ZFA:0000092 axis axis increased curvature , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000109 forebrain forebrain commissural neuron axon guidance disrupted , abnormal
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 ZFA:0000112 gut gut hypoplastic , abnormal
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 ZFA:0000217 inner ear inner ear quality , abnormal
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 ZFA:0000435 cranial nerve II cranial nerve II absent , abnormal
cranial nerve II decreased size , abnormal
cranial nerve II defasciculated , abnormal
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 ZFA:0000890 floor plate spinal cord region floor plate spinal cord region glial cell (sensu Vertebrata) increased size , abnormal
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 ZFA:0001094 whole organism whole organism bent , abnormal
whole organism curved , abnormal
whole organism curved dorsal , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001115 trunk trunk sigmoid , abnormal
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 ZFA:0001135 neural tube neural tube has extra parts of type radial glial cell , abnormal
neural tube apoptotic process increased process quality , abnormal
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 ZFA:0001259 forebrain ventricle forebrain ventricle has extra parts of type astrocyte , abnormal
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 ZFA:0001285 intersegmental vessel intersegmental vessel shortened , abnormal
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 ZFA:0005025 dorsal longitudinal anastomotic vessel dorsal longitudinal anastomotic vessel morphology , abnormal
dorsal longitudinal anastomotic vessel absent , abnormal
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 ZFA:0005176 CoSA CoSA decreased amount , abnormal
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 ZFA:0005177 VeLD VeLD axon guidance process quality , abnormal
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 ZFA:0005240 Kolmer-Agduhr neuron Kolmer-Agduhr neuron axon guidance process quality , abnormal
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 ZFA:0005249 vasculature vasculature branchiness , abnormal
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 ZFA:0009052 motor neuron motor neuron decreased amount , abnormal
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 ZFA:0009292 radial glial cell radial glial cell has fewer parts of type radial glial cell aster, abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000010948 kif11 / kinesin family member 11 / P52732* / Q6P9P6* / Kinesin-like protein KIF11 *  / complex / reaction






 

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